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CD243/MDR1 Mouse mAb - Primary antibody, specific to P Glycoprotein/CD243, Mouse IgG2a

COA COA
    Application:
  • Animal Model
  • Blocking
  • Depletion
  • Flow Cytometry
  • Functional Assay
  • IHC
  • Host species: Mouse
  • Reactive species: Human,Monkey
  • Isotype: Mouse IgG2a
  • Clone Number: UIC2
  • Conjugation: Unconjugated
In stock
Item Number
Ab119574
Grouped product items
SKU Size
Availability
 Price Qty
Ab119574-10μg
10μg
5
$49.90
Ab119574-50μg
50μg
2
$149.90
Ab119574-100μg
100μg
1
$199.90
Ab119574-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (UIC2); Mouse anti Human/Monkey CD243/MDR1 Antibody; in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models, in vitro MDR-1 blocking, IHC, Flow; Unconjugated

View related series
Click to view target information: ABCB1
ABCB1 (4) Accession#:P08183 (4) CD243 (3) Flow Cytometry (1158) Gene ID:5243 (4) P Glycoprotein (2)

Basic Description

Product Name CD243/MDR1 Mouse mAb - Primary antibody, specific to P Glycoprotein/CD243, Mouse IgG2a
Synonyms CLCS | MDR1 | P-GP | PGY1 | ABC20 | CD243 | GP170 | p-170 | ABC20 antibody | ABCB1 antibody | ATP binding cassette, sub family B (MDR/TAP), member 1 antibody | ATP-binding cassette sub-family B member 1 antibody | CD243 antibody | CLCS antibody | Colchici
Specifications & Purity Carrier Free, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host species Mouse
Specificity P Glycoprotein/CD243
Immunogen 3T3 fibroblasts transfected with human CD243 cDNA
Conjugation Unconjugated
Grade Azide Free, Carrier Free, Validated
Product Description

Mouse anti Human/Monkey CD243/MDR1 Antibody, Monoclonal (UIC2), could be used for in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models, in vitro MDR-1 blocking, IHC, Flow and so on.
Application:
in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models: Use at an assay dependent concentration.
in vitro MDR-1 blocking: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
Protein Function
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

Product Properties

Isotype Mouse IgG2a
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

ABCB1 Tchem Multidrug resistance protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD243/MDR1 Mouse mAb (Ab119574) - Flow Cytometry
Flow Cytometry analysis of HepG2 cells labelling CD243/MDR1 (red) with CD243/MDR1 Mouse mAb (Ab119574) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
IHC

Use at an assay dependent concentration.
Flow Cytometry

Use at an assay dependent concentration.
in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models

Use at an assay dependent concentration.
in vitro MDR-1 blocking

Use at an assay dependent concentration.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number Certificate Type Date Item
ZJ24F0809792 Certificate of Analysis Aug 20, 2024 Ab119574

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