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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab211169-10μg
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10μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$69.90
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Ab211169-25μg
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25μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$139.90
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Ab211169-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$329.90
|
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mAb (UIC2); Mouse anti Human/Monkey CD243/MDR1 Antibody (AF647); Flow Cytometry
| Product Name | CD243/MDR1 Mouse mAb (AF647) - Primary antibody, specific to P Glycoprotein/CD243 |
|---|---|
| Synonyms | CLCS | MDR1 | P-GP | PGY1 | ABC20 | CD243 | GP170 | p-170 | ABC20 antibody | ABCB1 antibody | ATP binding cassette, sub family B (MDR/TAP), member 1 antibody | ATP-binding cassette sub-family B member 1 antibody | CD243 antibody | CLCS antibody | Colchici |
| Specifications & Purity | ExactAb™, Validated, Ex:650nm, Em:668nm, 0.5 mg/mL |
| Biochemical and Physiological Mechanisms | Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. |
| Host species | Mouse |
| Specificity | P Glycoprotein/CD243 |
| Immunogen | 3T3 fibroblasts transfected with human CD243 cDNA |
| Positive Control | Flow: HepG2 cells |
| Conjugation | AF647 |
| Excitation(nm) | Red Laser(633nm) |
| Emission(nm) | 668nm |
| Ex/Em(nm) | Ex:650nm;Em:668nm |
| Grade | Em:668nm, Ex:650nm, ExactAb™, Validated |
| Product Description |
Mouse anti Human/Monkey CD243/MDR1 Antibody, Monoclonal (UIC2), could be used for in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models, in vitro MDR-1 blocking, IHC, Flow and so on. |
| Light Chain Type | kappa |
|---|---|
| Purification Method | Protein A purified |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at 2-8°C,Protected from light,Do not freeze |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CD243/MDR1 Mouse mAb (AF647) (Ab211169) - Flow Cytometry
Flow cytometry analysis of CD243/MDR1 expression by HepG2 cells (red) compared to an isotype control (blue). Cells were stained with CD243/MDR1 Mouse mAb (AF647) (Ab211169) at 0.3 μg/test for 1 hour at 4°C. Blue - Mouse IgG (AF647) (Ab190077). Black - Unlabelled control, cells without incubation with primary antibody.
| Application | Dilution info |
|---|---|
| Flow Cytometry | ≤1.0 μg/test. For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume. |
Starting at $56.90
Starting at $49.90