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CD243/MDR1 Mouse mAb (AF647) - Primary antibody, specific to P Glycoprotein/CD243

    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human,Monkey
  • Isotype: Mouse IgG2a
  • Clone Number: UIC2
  • Conjugation: AF647
In stock
Item Number
Ab211169
Grouped product items
SKU Size
Availability
Price Qty
Ab211169-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab211169-25μg
25μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
Ab211169-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90

mAb (UIC2); Mouse anti Human/Monkey CD243/MDR1 Antibody (AF647); Flow Cytometry

Basic Description

Product Name CD243/MDR1 Mouse mAb (AF647) - Primary antibody, specific to P Glycoprotein/CD243
Synonyms CLCS | MDR1 | P-GP | PGY1 | ABC20 | CD243 | GP170 | p-170 | ABC20 antibody | ABCB1 antibody | ATP binding cassette, sub family B (MDR/TAP), member 1 antibody | ATP-binding cassette sub-family B member 1 antibody | CD243 antibody | CLCS antibody | Colchici
Specifications & Purity ExactAb™, Validated, Ex:650nm, Em:668nm, 0.5 mg/mL
Biochemical and Physiological Mechanisms Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Host species Mouse
Specificity P Glycoprotein/CD243
Immunogen 3T3 fibroblasts transfected with human CD243 cDNA
Positive Control Flow: HepG2 cells
Conjugation AF647
Excitation(nm) Red Laser(633nm)
Emission(nm) 668nm
Ex/Em(nm) Ex:650nm;Em:668nm
Grade Em:668nm, Ex:650nm, ExactAb™, Validated
Product Description

Mouse anti Human/Monkey CD243/MDR1 Antibody, Monoclonal (UIC2), could be used for in vivo MDR-1 blocking/depletion in xenogeneic murine tumor models, in vitro MDR-1 blocking, IHC, Flow and so on.

Product Properties

Light Chain Type kappa
Purification Method Protein A purified
Concentration 0.5 mg/mL
Storage Temp Store at 2-8°C,Protected from light,Do not freeze
Shipped In Wet ice
Stability And Storage The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Associated Targets(Human)

ABCB1 Tchem Multidrug resistance protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

CD243/MDR1 Mouse mAb (AF647) (Ab211169) - Flow Cytometry
Flow cytometry analysis of CD243/MDR1 expression by HepG2 cells (red) compared to an isotype control (blue). Cells were stained with CD243/MDR1 Mouse mAb (AF647) (Ab211169) at 0.3 μg/test for 1 hour at 4°C. Blue - Mouse IgG (AF647) (Ab190077). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow Cytometry

≤1.0 μg/test. For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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