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CD22 Mouse mAb - Primary antibody, specific to CD22, Mouse IgG1

COA COA
    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: HIB22
  • Conjugation: Unconjugated
In stock
Item Number
Ab006558
Grouped product items
SKU Size
Availability
 Price Qty
Ab006558-10μg
10μg
10
$26.90
Ab006558-50μg
50μg
4
$69.90
Ab006558-100μg
100μg
2
$109.90
Ab006558-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (HIB22); Mouse anti Human CD22 Antibody; Flow; Unconjugated

View related series
Click to view target information: CD22
Accession#:P20273 (13) CD22 (15) Flow Cytometry (1158) Gene ID:933 (14)

Basic Description

Product Name CD22 Mouse mAb - Primary antibody, specific to CD22, Mouse IgG1
Synonyms B-cell receptor CD22 | BL-CAM | B-lymphocyte cell adhesion molecule | CD22 antigenMGC130020 | CD22 molecule | CD22 | sialic acid binding Ig-like lectin 2 | Sialic acid-binding Ig-like lectin 2 | Siglec2 | Siglec-2 | SIGLEC2FLJ22814 | T-cell surface antige
Specifications & Purity Carrier Free, ExactAb™, Validated, See COA
Host species Mouse
Specificity CD22
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD22 Antibody, Monoclonal (HIB22), could be used for Flow and so on.
Application:
Flow: ＜0.5µg/100w cells
Protein Function
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (36 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

CD22 Tclin B-cell receptor CD22 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD22 Mouse mAb (Ab006558) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD22 (red) with CD22 Mouse mAb (Ab006558) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (AF647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow

< 0.5µg/100w cells

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0102459 Certificate of Analysis Jan 17, 2024 Ab006558
ZJ24F0102460 Certificate of Analysis Jan 17, 2024 Ab006558
ZJ24F0102461 Certificate of Analysis Jan 17, 2024 Ab006558

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