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Camidanlumab (anti-CD25) - Primary antibody, specific to IL2RA, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182785
Grouped product items
SKU Size
Availability
Price Qty
Ab182785-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab182785-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
Ab182785-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$649.90
Ab182785-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,029.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Camidanlumab (anti-CD25) - Primary antibody, specific to IL2RA, Human IgG1
Synonyms Interleukin 2 receptor alpha chain antibody | CD25 antibody | CD25 antigen antibody | IDDM10 antibody | IL 2 receptor alpha subunit antibody | IL-2 receptor subunit alpha antibody | IL-2-RA antibody | IL-2R subunit alpha antibody | IL2 RA antibody | IL2 R
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL2RA
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Camidanlumab (anti-CD25) is a CD25 monoclonal antibody. Camidanlumab (anti-CD25) targets the cell-surface antigen CD25, which is over-expressed on a variety of hematological tumors and shows limited expression on normal tissues. Camidanlumab (anti-CD25) can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including lymphoma and leukemia.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 921618-45-3

Associated Targets(Human)

IL2RA Tclin Interleukin-2 receptor subunit alpha (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
IL2RA Tclin Interleukin-2 receptor alpha chain (2 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Camidanlumab (anti-CD25) (Ab182785) - Flow Cytometry
Flow Cytometry analysis of 10 μg/mL PHA stimulated 3 days human peripheral blood lymphocytes labelling CD25 with Camidanlumab (anti-CD25) (Ab182785) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Camidanlumab (anti-CD25) (Ab182785) - Flow Cytometry
Flow Cytometry analysis of 10 μg/mL PHA stimulated 3 days human peripheral blood lymphocytes labelling CD25 (red) with Camidanlumab (anti-CD25) (Ab182785) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Camidanlumab (anti-CD25) (Ab182785) - ELISA
Immobilized Human-huCD25-ECD-hFc Protein at 2.0 μg/mL can bind Camidanlumab (anti-CD25) (Ab182785) with the EC₅₀ of 9.5 ng/mL

Camidanlumab (anti-CD25) (Ab182785) - SEC
The purity of Camidanlumab (anti-CD25) (Ab182785) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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