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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182785-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$49.90
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Ab182785-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$249.90
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Ab182785-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$649.90
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Ab182785-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,029.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Camidanlumab (anti-CD25) - Primary antibody, specific to IL2RA, Human IgG1 |
|---|---|
| Synonyms | Interleukin 2 receptor alpha chain antibody | CD25 antibody | CD25 antigen antibody | IDDM10 antibody | IL 2 receptor alpha subunit antibody | IL-2 receptor subunit alpha antibody | IL-2-RA antibody | IL-2R subunit alpha antibody | IL2 RA antibody | IL2 R |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL2RA |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Camidanlumab (anti-CD25) is a CD25 monoclonal antibody. Camidanlumab (anti-CD25) targets the cell-surface antigen CD25, which is over-expressed on a variety of hematological tumors and shows limited expression on normal tissues. Camidanlumab (anti-CD25) can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including lymphoma and leukemia.
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| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 921618-45-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Camidanlumab (anti-CD25) (Ab182785) - Flow Cytometry
Flow Cytometry analysis of 10 μg/mL PHA stimulated 3 days human peripheral blood lymphocytes labelling CD25 with Camidanlumab (anti-CD25) (Ab182785) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Camidanlumab (anti-CD25) (Ab182785) - Flow Cytometry
Flow Cytometry analysis of 10 μg/mL PHA stimulated 3 days human peripheral blood lymphocytes labelling CD25 (red) with Camidanlumab (anti-CD25) (Ab182785) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Camidanlumab (anti-CD25) (Ab182785) - ELISA
Immobilized Human-huCD25-ECD-hFc Protein at 2.0 μg/mL can bind Camidanlumab (anti-CD25) (Ab182785) with the EC₅₀ of 9.5 ng/mL
Camidanlumab (anti-CD25) (Ab182785) - SEC
The purity of Camidanlumab (anti-CD25) (Ab182785) is more than 95% verified by HPLC.
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