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Blinatumomab (anti-CD3&CD19) - Primary antibody, specific to CD3E; CD19, Antibody of CD19;Antibody of CD3e, Antibody of CD19;Antibody of CD3e

    Application:
  • ELISA
  • Flow Cytometry
  • Host species: Human
  • Reactive species: Human
  • Conjugation: Unconjugated
In stock
Item Number
Ab175475
Grouped product items
SKU Size
Availability
Price Qty
Ab175475-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
Ab175475-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,259.90

Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; CHO; ELISA, Flow Cytometry; Unconjugated

Basic Description

Product Name Blinatumomab (anti-CD3&CD19) - Primary antibody, specific to CD3E; CD19, Antibody of CD19;Antibody of CD3e
Synonyms CD3 epsilon antibody | CD3e antibody | CD3e antigen antibody | CD3e antigen epsilon polypeptide (TiT3 complex) antibody | CD3E antigen epsilon polypeptide antibody | CD3E antigen, epsilon subunit antibody | CD3e molecule epsilon antibody | CD3e molecule,
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Moligand™, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD3E; CD19
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Moligand™, Recombinant, Validated
Action Type CROSS-LINKING AGENT
Mechanism of action Antibody of CD19;Antibody of CD3e
Product Description

Blinatumomab (anti-CD3&CD19) is a bispecific monoclonal antibody which can specifically targets the CD19 antigen present on B cells. Blinatumomab (anti-CD3&CD19) can be used for the research of acute lymphoblastic leukemia.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
≤1.0EU/mg

Product Properties

Light Chain Type kappa
SDS-PAGE 54.05 kDa
Purification Method Nickel affinity chromatography+Molecular sieve
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 12 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS 853426-35-4

Associated Targets(Human)

CD19 Tclin B-lymphocyte antigen CD19 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CD3E Tclin T cell surface glycoprotein CD3 (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Blinatumomab (anti-CD3&CD19) (Ab175475) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD3&CD19 (red) with Blinatumomab (anti-CD3&CD19) (Ab175475) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Blinatumomab (anti-CD3&CD19) (Ab175475) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3&CD19 (red) with Blinatumomab (anti-CD3&CD19) (Ab175475) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Blinatumomab (anti-CD3&CD19) (Ab175475) - SEC
The purity of Blinatumomab (anti-CD3&CD19) (Ab175475) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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