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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175475-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$239.90
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Ab175475-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,259.90
|
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Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; CHO; ELISA, Flow Cytometry; Unconjugated
| Product Name | Blinatumomab (anti-CD3&CD19) - Primary antibody, specific to CD3E; CD19, Antibody of CD19;Antibody of CD3e |
|---|---|
| Synonyms | CD3 epsilon antibody | CD3e antibody | CD3e antigen antibody | CD3e antigen epsilon polypeptide (TiT3 complex) antibody | CD3E antigen epsilon polypeptide antibody | CD3E antigen, epsilon subunit antibody | CD3e molecule epsilon antibody | CD3e molecule, |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Moligand™, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD3E; CD19 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Moligand™, Recombinant, Validated |
| Action Type | CROSS-LINKING AGENT |
| Mechanism of action | Antibody of CD19;Antibody of CD3e |
| Product Description |
Blinatumomab (anti-CD3&CD19) is a bispecific monoclonal antibody which can specifically targets the CD19 antigen present on B cells. Blinatumomab (anti-CD3&CD19) can be used for the research of acute lymphoblastic leukemia. |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 54.05 kDa |
| Purification Method | Nickel affinity chromatography+Molecular sieve |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 12 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 853426-35-4 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Blinatumomab (anti-CD3&CD19) (Ab175475) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD3&CD19 (red) with Blinatumomab (anti-CD3&CD19) (Ab175475) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Blinatumomab (anti-CD3&CD19) (Ab175475) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3&CD19 (red) with Blinatumomab (anti-CD3&CD19) (Ab175475) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Blinatumomab (anti-CD3&CD19) (Ab175475) - SEC
The purity of Blinatumomab (anti-CD3&CD19) (Ab175475) is more than 95% verified by HPLC.