Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab170495-100μg
|
100μg |
10
|
$49.90
|
|
|
Ab170495-1mg
|
1mg |
3
|
$240.90
|
|
|
Ab170495-5mg
|
5mg |
1
|
$606.90
|
|
|
Ab170495-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,005.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Atibuclimab (anti-CD14) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD14, >95%, high purity, Human IgG4, Antibody of CD14 molecule |
|---|---|
| Synonyms | CD 14 antibody | CD_antigen=CD14 antibody | CD14 antibody | CD14 antigen antibody | CD14 molecule antibody | CD14_HUMAN antibody | LPS-R antibody | Mo2 antibody | Monocyte differentiation antigen CD14 antibody | Monocyte differentiation antigen CD14 urina |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD14 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTIBODY |
| Mechanism of action | Antibody of CD14 molecule |
| Product Description |
Atibuclimab (anti-CD14) is a recombinant monoclonal against CD14. Atibuclimab can be used for the research of amyotrophic lateral sclerosis. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG4 |
| Light Chain Type | kappa |
| SDS-PAGE | 28.0 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 167.3 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2417175-94-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Atibuclimab (anti-CD14) (Ab170495) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD14 (red) with Atibuclimab (anti-CD14) (Ab170495). Goat Anti-Human IgG (FITC) (Ab175834) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Atibuclimab (anti-CD14) (Ab170495) - SEC
The purity of Atibuclimab (anti-CD14) (Ab170495) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 25, 2024 | Ab170495 | |
| Certificate of Analysis | Mar 25, 2024 | Ab170495 | |
| Certificate of Analysis | Mar 25, 2024 | Ab170495 |
Starting at $25.90
Starting at $19.90
Starting at $29.90
Starting at $19.90
Starting at $45.90
Starting at $59.90
Starting at $39.90
Starting at $29.90
Starting at $19.90
Starting at $58.90
Starting at $39.90
Starting at $41.90
Starting at $30.90
Starting at $59.90
Starting at $26.90
Starting at $30.90
Starting at $53.90
Starting at $23.90
Starting at $62.90
Starting at $62.90