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CAT-2200 (anti-CTLA-8) - Primary antibody, specific to IL17A, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209865
Grouped product items
SKU Size
Availability
Price Qty
Ab209865-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209865-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209865-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209865-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name CAT-2200 (anti-CTLA-8) - Primary antibody, specific to IL17A, Human IgG1
Synonyms CTLA 8 antibody | CTLA-8 antibody | CTLA8 antibody | cytotoxic T lymphocyte associated antigen 8 antibody | Cytotoxic T lymphocyte associated protein 8 antibody | Cytotoxic T lymphocyte associated serine esterase 8 antibody | Cytotoxic T-lymphocyte-associ
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. Post-translational: Found both in glycosylated and nonglycosylated forms.
Host species Human
Specificity IL17A
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

CAT-2200 (anti-CTLA-8) is a human monoclonal antibody against IL-17A (interleukin-17A) that can potently neutralize the effects of recombinant and native human IL-17A.

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 145 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

IL17A Tclin Interleukin-17A (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CAT-2200 (anti-CTLA-8) (Ab209865) - ELISA
Immobilized Recombinant Human CTLA-8 / IL-17a protein at 2.0 μg/mL can bind CAT-2200 (anti-CTLA-8) (Ab209865) with the EC₅₀ of 7.35 ng/mL.

CAT-2200 (anti-CTLA-8) (Ab209865) - SEC
The purity of CAT-2200 (anti-CTLA-8) (Ab209865) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Alternative Products

Solution Calculators

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