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Budigalimab (anti-PD-1) - Primary antibody, specific to PDCD1, Human IgG1, INHIBITOR of Programmed cell death protein 1 inhibitor, INHIBITOR of Programmed cell death protein 1 inhibitor

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182803
Grouped product items
SKU Size
Availability
 Price Qty
Ab182803-100μg
100μg
10
$59.90
Ab182803-1mg
1mg
4
$289.90
Ab182803-5mg
5mg
1
$749.90
Ab182803-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: PDCD1
Accession#:Q15116 (38) CD279 (28) Gene ID:5133 (38) PD-1 (9) PDCD1 (39)

Basic Description

Product Name Budigalimab (anti-PD-1) - Primary antibody, specific to PDCD1, Human IgG1, INHIBITOR of Programmed cell death protein 1 inhibitor
Synonyms CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 antibody | PD-1 antibody | PD1 antibody | PDCD 1 antibody | PDCD1_HUMAN antibody | PDCD1 antibody | Programmed cell death 1 antibody | Progr
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity PDCD1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Programmed cell death protein 1 inhibitor
Product Description

Budigalimab (anti-PD-1) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab (anti-PD-1) is Fc mutated thus to reduce Fc receptor interactions and limit effector function.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 144.76 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2098225-93-3

Associated Targets(Human)

PDCD1 Tclin Programmed cell death protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
PDCD1 Tclin Programmed cell death protein 1 (14 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Budigalimab (anti-PD-1) (Ab182803) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-1 (red) with Budigalimab (anti-PD-1) (Ab182803) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Budigalimab (anti-PD-1) (Ab182803) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) MOLT-4 cells labelling PD-1 (red) with Budigalimab (anti-PD-1) (Ab182803) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Budigalimab (anti-PD-1) (Ab182803) - ELISA
Immobilized Recombinant Human PD-1 protein (rp176241) at 1.0 μg/mL can bind Budigalimab (anti-PD-1) (Ab182803) with the EC₅₀ of 17.44 ng/mL.

Budigalimab (anti-PD-1) (Ab182803) - SEC
The purity of Budigalimab (anti-PD-1) (Ab182803) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607190 Certificate of Analysis Jun 21, 2024 Ab182803
ZJ24F0607189 Certificate of Analysis Jun 21, 2024 Ab182803
ZJ24F0607188 Certificate of Analysis Jun 21, 2024 Ab182803

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