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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170567-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab170567-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$519.90
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Ab170567-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab170567-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,239.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Ozanezumab (anti-RTN4), for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to RTN4, >95%, high purity, Human IgG1, Antibody of reticulon 4 |
|---|---|
| Synonyms | Foocen | Neurite outgrowth inhibitor | Neuroendocrine-specific protein | Neuroendocrine-specific protein C homolog | Nogo protein | NSP | Reticulon-5 | RTN-x |
| Specifications & Purity | Carrier Free, Recombinant, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Invo |
| Host species | Human |
| Specificity | RTN4 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Grade | Animal Free, Azide Free, Carrier Free, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | Antibody of reticulon 4 |
| Product Description |
Ozanezumab (anti-RTN4) is a recombinant monoclonal antibody to RTN4. Ozanezumab can be used in amyotrophic lateral sclerosis (ALS) and multiple sclerosis research. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1310680-64-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Ozanezumab (anti-RTN4) (Ab170567) - ELISA
Immobilized Recombinant Human NOGO-A(586-785)/RTN4-His protein at 2.0 μg/mL can bind Ozanezumab (anti-RTN4) (Ab170567) with the EC50 of 13.32 ng/mL.
Ozanezumab (anti-RTN4) (Ab170567) - SEC
The purity of Ozanezumab (anti-RTN4) (Ab170567) is more than 95% verified by HPLC.
Starting at $109.90
Starting at $109.90