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ZLN005 - 10mM in DMSO, high purity , CAS No.49671-76-3

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ZLN005 - 10mM in DMSO, high purity , CAS No.49671-76-3

COA

Grade & Purity:

10mM in DMSO

Cas Number: 49671-76-3
Molecular Weight: 250.34
PubChem CID: 899323

In stock

Item Number

Z424281

Grouped product items
SKU	Size	Availability	Price	Qty
Z424281-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90

PGC-1α transcriptional activator. Activates AMPK.

View related series

Autophagy (1917) Compound libraries (12325) Glucose Metabolism (1943)

Basic Description

Synonyms	ZLN005 \| 49671-76-3 \| 2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazole \| 2-(4-tert-butylphenyl)-1H-benzimidazole \| 2-(4-tert-butylphenyl)-1H-benzo[d]imidazole \| CBMicro_034305 \| SCHEMBL6755306 \| CHEMBL4303368 \| DTXSID60358473 \| EX-A690 \| TQS-168 \| ZLN 005 \| ZLN-005 \| 3WT26285WB \| HMS36
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	PGC-1α transcriptional activator. Activates AMPK. Stimulates PGC-1α expression. Increases fat oxidation. Improves glucose and pyruvate tolerance. Increases insulin sensitivity. Shows antidiabetic effects in vivo.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Benzimidazoles
    - Subclass Phenylbenzimidazoles

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Benzimidazoles
Subclass	Phenylbenzimidazoles
Intermediate Tree Nodes	Not available
Direct Parent	Phenylbenzimidazoles
Alternative Parents	Phenylimidazoles Phenylpropanes Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Phenylbenzimidazole - 2-phenylimidazole - Phenylpropane - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as phenylbenzimidazoles. These are compounds containing a phenylbenzimidazole skeleton, which consists of a benzimidazole moiety where its imidazole ring is attached to a phenyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-(4-tert-butylphenyl)-1H-benzimidazole
INCHI	InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)
InChIKey	LQUNNCQSFFKSSK-UHFFFAOYSA-N
Smiles	CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
Isomeric SMILES	CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
WGK Germany	3
PubChem CID	899323
Molecular Weight	250.34

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	250.340 g/mol
XLogP3	4.900
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	2
Exact Mass	250.147 Da
Monoisotopic Mass	250.147 Da
Topological Polar Surface Area	28.700 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	299.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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