| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| V345133-5mg |
5mg |
期货  |
| |
| V345133-10mg |
10mg |
现货 |
|
| 英文别名 | HCW4G0O030 | Q27279863 | FT-0675851 | CID 135565536 | 2-[[2-hydroxy-5-[(5-methyltetrazol-1-yl)iminomethyl]phenyl]-(4-hydroxyphenyl)methyl]-4-[(5-methyltetrazol-1-yl)iminomethyl]phenol | UNII-HCW4G0O030 | (4E)-2-[(4-hydroxyphenyl)-[(3E)-3-[[(5-methyltetraz |
|---|---|
| 规格或纯度 | ≥98% |
| 英文名称 | VP 14637 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
VP 14637抑制人呼吸道合胞病毒（HRSV），这是一种主要的呼吸道病毒病原体，在所有年龄段以及广泛的患者群体中均引起中度至重度上呼吸道和下呼吸道感染。VP-14637通过结合到F蛋白内核中的小疏水腔中（与HR1和HR2域同时相互作用）来抑制呼吸道合胞病毒融合。 VP 14637 inhibits human respiratory syncytial virus (HRSV) a major respiratory viral pathogen causing moderate to severe upper and lower respiratory tract infections in all ages and across a wide range of patient populations. VP-14637 inhibits respiratory syncytial virus fusion by binding into a small hydrophobic cavity in the inner core of F protein, interacting simultaneously with both the HR1 and HR2 domains. |
| 纯度 | ≥98% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | 2-[[2-hydroxy-5-[(5-methyltetrazol-1-yl)iminomethyl]phenyl]-(4-hydroxyphenyl)methyl]-4-[(5-methyltetrazol-1-yl)iminomethyl]phenol |
| INCHI | 1S/C25H22N10O3/c1-15-28-30-32-34(15)26-13-17-3-9-23(37)21(11-17)25(19-5-7-20(36)8-6-19)22-12-18(4-10-24(22)38)14-27-35-16(2)29-31-33-35/h3-14,25,36-38H,1-2H3 |
| InChi Key | BLUJRJMLDHEMRX-UHFFFAOYSA-N |
| Smiles | CC1=NN=NN1N=CC2=CC(=C(C=C2)O)C(C3=CC=C(C=C3)O)C4=C(C=CC(=C4)C=NN5C(=NN=N5)C)O |
| Isomeric SMILES | CC1=NN=NN1N=CC2=CC(=C(C=C2)O)C(C3=CC=C(C=C3)O)C4=C(C=CC(=C4)C=NN5C(=NN=N5)C)O |
| PubChem CID | 135565536 |
| 分子量 | 510.51 |
| 溶解性 | Soluble in DMSO, and THF. |
|---|---|
| 熔点 | >225° C (dec.) |
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