| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| U614695-5mg |
5mg |
期货  |
| |
| U614695-25mg |
25mg |
期货 |
|
| 别名 | 乌赞塞提布 |
|---|---|
| 英文别名 | INCB-053914 | INCB053914 |
| 规格或纯度 | Moligand™ |
| 英文名称 | uzansertib |
| 作用类型 | 抑制剂 |
| 作用机制 | Pim-1 原癌基因抑制剂；丝氨酸/苏氨酸激酶；Pim-2 原癌基因抑制剂；丝氨酸/苏氨酸激酶；Pim-3 原癌基因抑制剂；丝氨酸/苏氨酸激酶 |
| INCHI | 1S/C26H26F3N5O3/c1-12-10-34(11-17(30)25(12)36)24-13-5-8-20(35)22(13)31-9-19(24)33-26(37)18-7-6-16(29)23(32-18)21-14(27)3-2-4-15(21)28/h2-4,6-7,9,12,17,20,25,35-36H,5,8,10-11,30H2,1H3,(H,33,37)/t12-,17+,20+,25+/m1/s1 |
|---|---|
| InChi Key | PTORCEYGCGXHDH-SGQXWQAPSA-N |
| Smiles | C[C@@H]1CN(C[C@@H]([C@H]1O)N)c1c(cnc2c1CC[C@@H]2O)NC(=O)c1ccc(c(n1)c1c(F)cccc1F)F |
| PubChem CID | 129606875 |
| 1. Koblish H, Li YL, Shin N, Hall L, Wang Q, Wang K, Covington M, Marando C, Bowman K, Boer J et al.. (2018) Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies.. PLoS ONE, 13 (6): (e0199108). [PMID:29927999] |
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