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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| T129208-50mg |
50mg |
现货 ![]() |
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| T129208-250mg |
250mg |
现货 ![]() |
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| T129208-1g |
1g |
现货 ![]() |
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| T129208-5g |
5g |
现货 ![]() |
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| T129208-10g |
10g |
现货 ![]() |
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| T129208-25g |
25g |
现货 ![]() |
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| T129208-100g |
100g |
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| 别名 | 特比萘芬 | (E)-N-(6,6-二甲基-2-庚烯-4-炔基)-N-甲基-1-萘甲胺 | 反-N-(6,6-二甲基-2-庚烯-4-炔基)-N-甲基-1-萘甲胺 | (E)-N,6,6-三甲基-N-(萘-1-基甲基)庚-2-烯-4-炔-1-胺 |
|---|---|
| 英文别名 | DT 067 | SF 86-327 | Lamisil | Terbinex | TDT 067 | MFCD00242672 | TERBINAFINE [USAN] | (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine | D02375 | N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine | 1-Naphth |
| 规格或纯度 | ≥99% |
| 英文名称 | Terbinafine |
| 生化机理 | 特比萘芬是一种烯丙基胺类抗真菌剂,对多种皮癣菌、霉菌和某些二形真菌有杀真菌活性,对白色念珠菌有杀真菌活性。 |
| 应用 | Used to treat infections caused by a fungus. |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 作用机制 | 角鲨烯单氧化酶抑制剂 |
| 产品介绍 |
Terbinafine 用于治疗真菌感染,可以杀死真菌或防止其生长。Used to treat infections caused by a fungus. Terbinafine is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth. |
| 纯度 | ≥99% |
| ALogP | 5.6 |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| PubChem SID | 504760580 |
|---|---|
| EC号 | 618-706-8 |
| 分子类型 | 小分子 |
| IIUPAC Name | (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine |
| INCHI | 1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+ |
| InChi Key | DOMXUEMWDBAQBQ-WEVVVXLNSA-N |
| Smiles | CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21 |
| Isomeric SMILES | CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21 |
| 关联CAS | 91161-71-6 |
| PubChem CID | 1549008 |
| MeSH Entry Terms | (E)-N-(6,6-dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride;DA 5505;Lamisil;SF 86 327;SF 86-327;SF 86327;SF-86-327;SF86327;TDT 067;TDT-067;TDT067;terbinafine;terbinafine hydrochloride;Terbinafine, (Z)-;terbinafine, (Z)-isomer |
| 分子量 | 291.43 |
| 溶解性 | Soluble in DMSO (≥58 mg/mL) at 25 °C, water (<1 mg/mL) at 25 °C, and ethanol (≥58 mg/mL) at 25 °C. |
|---|---|
| 敏感性 | 对热敏感 |
| 熔点 | 43 °C |
| 分子量 | 291.400 g/mol |
| XLogP3 | 5.600 |
| 氢键供体数Hydrogen Bond Donor Count | 0 |
| 氢键受体数Hydrogen Bond Acceptor Count | 1 |
| 可旋转键计数Rotatable Bond Count | 5 |
| 精确质量Exact Mass | 291.199 Da |
| 单同位素质量Monoisotopic Mass | 291.199 Da |
| 拓扑极表面积Topological Polar Surface Area | 3.200 Ų |
| 重原子数Heavy Atom Count | 22 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 428.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 1 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 1 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS09 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 |
| 预防措施声明 |
P273: 避免释放到环境中。 P391: 收集溢出物 P501: 将内容物/容器处理到。。。 |
| Merck Index | 9156 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 | |
| 分析证书 | T129208 |
| 1. Yue Qun, Meng Jie, Qiu Yue, Yin Miaomiao, Zhang Liwen, Zhou Weiping, An Zhiqiang, Liu Zihe, Yuan Qipeng, Sun Wentao, Li Chun, Zhao Huimin, Molnár István, Xu Yuquan, Shi Shuobo. (2023) A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi. Nature Communications, 14 (1): (1-10). [PMID:37460548] [10.1038/s41467-023-40027-0] |
| 2. Meng Wang, Yanwen Zhou, Zhaohui Wang. (2023) Unearth the ultrapotent intrinsic fungicidal efficacy of the surface-piercing CuFeSe2-PVP nano-blade. CHEMICAL ENGINEERING JOURNAL, 464 (142603). [10.1016/j.cej.2023.142603] |
| 3. Hui Lu, Wanqian Li, Malcolm Whiteway, Hongkang Wang, Shuo Zhu, Zhe Ji, Yanru Feng, Lan Yan, Ting Fang, Liping Li, Tingjunhong Ni, Xiaolong Zhang, Quanzhen Lv, Zichao Ding, Lijuan Qiu, Dazhi Zhang, Yuanying Jiang. (2022) A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols. mBio, 14 (1): [PMID:36475771] [10.1128/mbio.02639-22] |
| 4. Guo Penghao, Chen Jianlong, Tan Yiwei, Xia Li, Zhang Weizheng, Li Xiaojie, Jiang Yujie, Li Ruiying, Chen Chunmei, Liao Kang, Peng Yaqin. (2022) Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China. Frontiers in Microbiology, 13 [PMID:36386677] [10.3389/fmicb.2022.992582] |
| 5. Xu Xue, Naseri Ali, Houbraken Jos, Akbari Farzaneh, Wang Xiaodong, Zhao Rongfen, Zhang Hong, Najafzadeh Mohammad Javad, Deng Shuwen. (2021) Identification and in vitro antifungal susceptibility of causative agents of onychomycosis due to Aspergillus species in Mashhad, Iran. Scientific Reports, 11 (1): (1-8). [PMID:33762586] [10.1038/s41598-021-86038-z] |