花旗松素

27篇引用文献

COA

级别和纯度:

分析标准品

≥98%

CAS编号: 480-18-2
分子式: C₁₅H₁₂O₇
分子量: 304.25
Beilstein号: 5299277
EC号: 207-543-4
MDL号: MFCD00006845
PubChem编号: 439533

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货号 (SKU)	包装规格	是否现货
T117991-25mg	25mg	现货
T117991-100mg	100mg	现货
T117991-250mg	250mg	现货
T117991-1g	1g	现货

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Amino Acid/Protein Metabolism (4559) Autophagy (2848) Extrinsic Pathway (1228) Metabolic Enzyme/Protease (4889) Tyrosinase (72) 黄酮类 (21)

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基本描述

别名	二氢槲皮素,紫杉叶素 \| (2R,3R)-二氢槲皮素 \| (2R,3R)-3,3′,4′,5,7-五羟基黄烷酮 \| (+)-花旗松素
英文别名	2,3-Dihydroquercetin \| Lariksin \| (+)-Dihydroquercetin \| Distylin \| Lavitol \| (+)-(2R,3R)-dihydroquercetin \| (+/-)-Taxifolin \| Diquertin \| Taxifoliol \| (+)-Taxifolin \| Flamena D \| TAXIFOLIN \| dihydroquercetin \| (2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone
规格或纯度	分析标准品, ≥98%
英文名称	Taxifolin
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	花旗松素是一种植物类黄酮，在治疗冠心病、心绞痛、脑血栓、脑梗塞及后遗症等方面可能有应用。应用：利用高效液相色谱技术 (HPLC) 测定家兔血浆中的花旗松素，可作为引用标准。 Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae. Application： Taxifolin can be used as a reference standard for the determination of taxifolin in plasma of rabbit using high performance liquid chromatography technique(HPLC).
纯度	≥98%

关联靶点（人）

CA12 Tclin 碳酸酐酶12(Carbonic anhydrase 12) (0 活性数据)

点击查看靶蛋白信息： CA12

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CA7 Tclin 碳酸酐酶7(Carbonic anhydrase 7) (0 活性数据)

点击查看靶蛋白信息： CA7

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

名称和识别符

EC号	207-543-4
分子类型	小分子
IIUPAC Name	(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one
INCHI	1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
InChi Key	CXQWRCVTCMQVQX-LSDHHAIUSA-N
Smiles	C1=CC(=C(C=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
Isomeric SMILES	C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
关联CAS	17654-26-1
PubChem CID	439533
分子量	304.25
Beilstein号	5299277

化学和物理性质

密度	1.702
敏感性	对热敏感；对空气敏感
熔点	242 °C
分子量	304.250 g/mol
XLogP3	1.500
氢键供体数Hydrogen Bond Donor Count	5
氢键受体数Hydrogen Bond Acceptor Count	7
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	304.058 Da
单同位素质量Monoisotopic Mass	304.058 Da
拓扑极表面积Topological Polar Surface Area	127.000 Å²
重原子数Heavy Atom Count	22
形式电荷Formal Charge	0
复杂度Complexity	428.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	2
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	Warning
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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找到10个结果

批号(Lot Number)	证书类型	货号
D2014038	分析证书	T117991
G2523389	分析证书	T117991
G2523390	分析证书	T117991
H2310056	分析证书	T117991
H2422514	分析证书	T117991
H2422515	分析证书	T117991
H2422525	分析证书	T117991
I2214741	分析证书	T117991
I2103432	分析证书	T117991
C1412096	分析证书	T117991

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引用文献

1. Chengyun He, Lu Bai, Daqun Liu, Benguo Liu. (2023) Interaction mechanism of okra (Abelmoschus esculentus L.) seed protein and flavonoids: Fluorescent and 3D-QSAR studies. Food Chemistry-X, 20 (101023). [PMID:38144792] [10.1016/j.fochx.2023.101023]
2. Xia Chenjie, Zhu Hongliu, Hu Changhui, Liu Jie, Hua Haibing, Yang Jianqiu, Chen Zhipeng, Gao Yihong. (2023) Simultaneous Determination of Three Flavonoids in Rat Plasma of Masson Pinus Needles (Pinus massoniana L.) Extracts by UHPLC-MS/MS and Application to Pharmacokinetics Studies after Oral and Transdermal Administration. JOURNAL OF CHROMATOGRAPHIC SCIENCE, [PMID:37647634] [10.1093/chromsci/bmad074]
3. Yuan Meng, Zihao Wei, Changhu Xue. (2023) Deciphering the interaction mechanism and binding mode between chickpea protein isolate and flavonoids based on experimental studies and molecular simulation. FOOD CHEMISTRY, 429 (136848). [PMID:37454615] [10.1016/j.foodchem.2023.136848]
4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [10.1016/j.fbio.2023.102508]
5. Leyong Yuan, Yan Sun, Ning Zhou, Weipeng Wu, Weidong Zheng, Yukun Wang. (2022) Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway. Frontiers in Pharmacology, 13 (845600). [PMID:35645837] [10.3389/fphar.2022.845600]
6. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H]
7. Chengshuai Li, Lijing Zhang, Decao Niu, Shuzhen Nan, Xiumei Miao, Xiaowei Hu, Hua Fu. (2021) Investigation of flavonoid expression and metabolite content patterns during seed formation of Artemisia sphaerocephala Krasch.. SEED SCIENCE RESEARCH, 31 (2): (136-148). [10.1017/S096025852100012X]
8. Hao Liu, Chenyun Gan, Houyin Shi, Kunyan Qu, Liuyang Jing, Muhe Lu, Benyu Su, Huayang Yu, Hang Yuan, Jingjing Chen, Ruirui Zhang, Weiling Zeng. (2021) Gastric floating pill enhances the bioavailability and drug efficacy of dihydromyricetin in vivo. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 61 (102279). [10.1016/j.jddst.2020.102279]
9. Chaonan Su, Caihong Li, Kang Sun, Wenjing Li, Rongxia Liu. (2020) Quantitative analysis of bioactive components in walnut leaves by UHPLC-Q-Orbitrap HRMS combined with QAMS. FOOD CHEMISTRY, 331 (127180). [PMID:32544651] [10.1016/j.foodchem.2020.127180]
10. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] [10.1016/j.saa.2020.118519]
11. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] [10.1016/j.foodchem.2020.126807]
12. Xiaoqin Wang, Wencong Jia, Guoyin Lai, Lijuan Wang, María del Mar Contreras, Daomao Yang. (2020) Extraction for profiling free and bound phenolic compounds in tea seed oil by deep eutectic solvents. JOURNAL OF FOOD SCIENCE, 85 (5): (1450-1461). [PMID:32249418] [10.1111/1750-3841.15019]
13. Rongxia Liu, Chaonan Su, Yumeng Xu, Kangle Shang, Kang Sun, Caihong Li, Jing Lu. (2020) Identifying potential active components of walnut leaf that action diabetes mellitus through integration of UHPLC-Q-Orbitrap HRMS and network pharmacology analysis. JOURNAL OF ETHNOPHARMACOLOGY, 253 (112659). [PMID:32058009] [10.1016/j.jep.2020.112659]
14. Long Ma, Xiuqi Cao, Haiyue Wang, Kui Lu, Ying Wang, Chunhao Tu, Yujie Dai, Yuanyuan Meng, Yuyin Li, Peng Yu, Shuli Man, Aipo Diao. (2019) Discovery of Myricetin as a Potent Inhibitor of Human Flap Endonuclease 1, Which Potentially Can Be Used as Sensitizing Agent against HT-29 Human Colon Cancer Cells. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (6): (1656–1665). [PMID:30694659] [10.1021/acs.jafc.8b05447]
15. Qian Liu, Hai-Long Wu, Zhi Liu, Rong Xiao, Tong Wang, Yong Hu, Yu-Jie Ding, Ru-Qin Yu. (2018) Chemometrics-assisted HPLC-DAD as a rapid and interference-free strategy for simultaneous determination of 17 polyphenols in raw propolis. Analytical Methods, 10 (46): (5577-5588). [10.1039/C8AY01986J]
16. Shuyu Shen, Rui Huang, Charlie Li, Wenyan Wu, Honglin Chen, John Shi, Shiguo Chen, Xingqian Ye. (2018) Phenolic Compositions and Antioxidant Activities Differ Significantly among Sorghum Grains with Different Applications. MOLECULES, 23 (5): (1203). [PMID:29772811] [10.3390/molecules23051203]
17. Han Peng, Zeyuan Deng, Xuan Chen, Yong Sun, Bing Zhang, Hongyan Li. (2018) Major chemical constituents and antioxidant activities of different extracts from the peduncles of Hovenia acerba Lindl. INTERNATIONAL JOURNAL OF FOOD PROPERTIES, [10.1080/10942912.2018.1497059]
18. Jiang Liu, Xiansheng Wang, Sheng Geng, Benguo Liu, Guizhao Liang. (2017) Inhibitory Mechanism of Taxifolin against α-Glucosidase Based on Spectrofluorimetry and Molecular Docking. Natural Product Communications, [10.1177/1934578X1701201116]
19. Wang Bohong, Qin Qian, Chang Mengmeng, Li Shuyan, Shi Xianzhe, Xu Guowang. (2018) Molecular interaction study of flavonoids with human serum albumin using native mass spectrometry and molecular modeling. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 410 (3): (827-837). [PMID:28840311] [10.1007/s00216-017-0564-7]
20. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang. (2017) Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr). Journal of Functional Foods, 32 (296). [10.1016/j.jff.2017.03.003]
21. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan. (2017) The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum. FOOD CHEMISTRY, 224 (26). [PMID:28159264] [10.1016/j.foodchem.2016.12.001]
22. Qinqin Wang, Lu Wang, Gaiping Li, Baoxian Ye. (2017) A simple and sensitive method for determination of taxifolin on palladium nanoparticles supported poly (diallyldimethylammonium chloride) functionalized graphene modified electrode. TALANTA, 164 (323). [PMID:28107936] [10.1016/j.talanta.2016.11.045]
23. Jiazeng Yang,Jincai Liang,Lei Shao,Lihong Liu,Ke Gao,Jun-Liang Zhang,Zhenjiao Sun,Wendong Xu,Pengcheng Lin,Rongmin Yu,Jiachen Zi. (2020-02-01) Green production of silybin and isosilybin by merging metabolic engineering approaches and enzymatic catalysis.. Metabolic engineering, 59 (44-52). [PMID:32004707]
24. Wang Weiting, Fan Xuanxuan, Chen Naidong, Hao Jingwen, Zhang Manman, Xie Zhengjun. (2025) An Ultra-High Performance Liquid Chromatography-Mass Spectrometry Method Based on Solid Phase Extraction Was Developed for the Analysis of Polyphenols in Prunus Mume Sieb. et Zucc. JOURNAL OF AOAC INTERNATIONAL, [PMID:40120078] [10.1093/jaoacint/qsaf028]
25. Xiaomeng Zhang, Xinquan Tian, Junyu Luo, Xiaoyang Wang, Shoupu He, Gaofei Sun, Ruidan Dong, Panhong Dai, Xiao Wang, Zhaoe Pan, Baojun Chen, Daowu Hu, Liru Wang, Baoyin Pang, Aishuang Xing, Guoyong Fu, Baoquan Wang, Jinjie Cui, Lei Ma, Xiongming Du. (2025) Identification of UDP-glucosyltransferase involved in the biosynthesis of phloridzin in Gossypium hirsutum. PLANT JOURNAL, 121 (3): (e17248). [PMID:39935137] [10.1111/tpj.17248]
26. Ye Wang, Shao-jie Chen, Ting Ma, Qiu Long, Lan Chen, Ke-xin Xu, Yu Cao. (2024) Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms. INTERNATIONAL IMMUNOPHARMACOLOGY, 138 (112517). [PMID:38924866] [10.1016/j.intimp.2024.112517]
27. Xiaomei Wen, Shanjie Han, Jiahui Wang, Yanxia Zhang, Lining Tan, Chen Chen, Baoyu Han, Mengxin Wang. (2024) The Flavor Characteristics, Antioxidant Capability, and Storage Year Discrimination Based on Backpropagation Neural Network of Organic Green Tea (Camellia sinensis) during Long-Term Storage. Foods, 13 (5): (753). [PMID:38472869] [10.3390/foods13050753]

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