| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| S755738-1g |
1g |
期货  |
| |
| S755738-5g |
5g |
期货 |
|
| 别名 | 1,8-二氨基-4-氮杂辛烷, N-(3-氨基丙基)-1,4-丁烷 | 亚精胺 | 1,8-二氨基-4-氮杂辛烷 | N-(3-氨基丙基)-1,4-二氨基丁烷 | N1-(3-氨基丙基)丁烷-1,4-二胺 |
|---|---|
| 英文别名 | 1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane | 1,8-Diamino-4-azaoctane | N-(3-Aminopropyl)-1,4-diaminobutane | N1-(3-Aminopropyl)butane-1,4-diamine |
| 规格或纯度 | UltraBio™, 分子生物学级, ≥99.5%(GC) |
| 英文名称 | Spermidine |
| 生化机理 | 亚精胺能调节各种细胞活动，如调节细胞生长发育、DNA稳定性和细胞凋亡。抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA，可用于DNA结合蛋白纯化。激活T4聚核苷酸激酶活性。抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA；激活T4聚核苷酸激酶活性。 |
| 储存温度 | 2-8°C储存,避光,充氩 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
亚精胺可作为：染色体分离缓冲液成分转录缓冲液成分均质化缓冲液成分应用： 亚精胺是一种多胺 和三价有机阳离子。亚精胺是一种天然存在的多胺化合物，具有多种生物性能它在基因表达中发挥着重要的作用，它参与DNA复制、转录和翻译过程。亚精胺对于细胞生长、增殖和分化非常重要，它影响细胞周期进程和组织发育。它具有抗氧化活性，通过清除自由基来保护细胞免受氧化应激。亚精胺还刺激细胞自噬，促进受损细胞器周转和蛋白质聚集，从而实现细胞稳态。它具有神经保护作用，支持神经元存活、突触可塑性，并预防神经退行性疾病。此外，亚精胺还可调节参与炎症和免疫反应的细胞信号通路。 Spermidine is a polyamine and a trivalent organic cation.Spermidine is a naturally occurring polyamine compound with diverse biochemical properties. It plays a vital role in gene expression, participating in DNA replication, transcription, and translation processes. Spermidine is crucial for cell growth, proliferation, and differentiation, influencing cell cycle progression and tissue development. It possesses antioxidant activity, safeguarding cells against oxidative stress by scavenging free radicals. Spermidine also stimulates autophagy, promoting the turnover of damaged organelles and protein aggregates for cellular homeostasis. With neuroprotective effects, it supports neuronal survival, synaptic plasticity, and guards against neurodegenerative diseases. Additionally, spermidine modulates cellular signaling pathways involved in inflammation and immune responses. Application: Spermidine has been used:
|
| 纯度 | ≥99.5%(GC) |
| pH | 12.0-13.5 (25 °C, 1 M in H 2 O) |
|---|
| EC号 | 204-689-0 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | N'-(3-aminopropyl)butane-1,4-diamine |
| INCHI | 1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 |
| InChi Key | ATHGHQPFGPMSJY-UHFFFAOYSA-N |
| Smiles | NCCCCNCCCN |
| Isomeric SMILES | C(CCNCCCN)CN |
| UN Number | 2735 |
| 分子量 | 145.25 |
| Beilstein号 | 1698591 |
| 溶解性 | H 2 O: 1 M at 20 °C, clear, colorless |
|---|---|
| 密度 | 0.925 g/mL at 25 °C (lit.) |
| 敏感性 | 对光线敏感；对湿度敏感；对光敏感 |
| 折光率 | 1.4785-1.4805 |
| 闪点(℉) | 230°F |
| 闪点(℃) | >110° |
| 沸点 | 128-130°C |
| 熔点 | 22-25°C |
| 分子量 | 145.250 g/mol |
| XLogP3 | -1.000 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 7 |
| 精确质量Exact Mass | 145.158 Da |
| 单同位素质量Monoisotopic Mass | 145.158 Da |
| 拓扑极表面积Topological Polar Surface Area | 64.099 Ų |
| 重原子数Heavy Atom Count | 10 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 56.800 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS05 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H314: 造成严重的皮肤灼伤和眼睛损伤 H318: 造成严重的眼睛损伤 |
| 预防措施声明 |
P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P363: 再次使用之前，请清洗受污染的衣物。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P302+P361+P354: 如果接触皮肤：立即脱掉所有被污染的衣服。立即用水冲洗几分钟。 P316: 立即寻求紧急医疗救助。 |
| WGK Germany | 3 |
| 个人防护装备 | Faceshields,Gloves,Goggles |
| 1. Jinxin Zheng, Xiaoju Liu, Yanpeng Xiong, Qingyin Meng, Peiyu Li, Fan Zhang, Xiaoming Liu, Zhiwei Lin, Qiwen Deng, Zewen Wen, Zhijian Yu. (2024) AMXT-1501 targets membrane phospholipids against Gram-positive and -negative multidrug-resistant bacteria. Emerging Microbes & Infections, [PMID:38422452] [10.1080/22221751.2024.2321981] |
| 2. Chengtuo Niu, Yiyang Liu, Heng Li, Chunfeng Liu, Qi Li. (2024) Biochemical and chemosensory characterization of doubanjiang fermented via two-stage controlled temperature. FOOD CHEMISTRY, 461 (140846). [PMID:39151351] [10.1016/j.foodchem.2024.140846] |
| 3. Yanan Liu, Jiacheng Gan, Fei Chen, Jian Chen, Huan Li, Yanbo Wang. (2024) Colorimetric detection of diamine using diamine oxidase and horseradish peroxidase co-incorporated hybrid microsphere as biomimetic cascade enzymes. FOOD CHEMISTRY, 456 (140008). [PMID:38870816] [10.1016/j.foodchem.2024.140008] |
| 4. Yamin Liu, Xunjiang Wang, Jiaojiao Wei, Kangning Fu, Yilin Chen, Linnan Li, Zhengtao Wang, Li Yang. (2024) Comprehensive Profiling of Amino Acids and Derivatives in Biological Samples: A Robust UHPLC-MS/MS Method for Investigating Acute Lung Injury. JOURNAL OF CHROMATOGRAPHY A, (464816). [PMID:38537486] [10.1016/j.chroma.2024.464816] |
| 5. Xueli Wang, Xueting Liu, Chunmei Sun, Yanwei Cheng, Zhen Li, Shuyi Qiu, Yongguang Huang. (2024) Effect of temperature on the quality and microbial community during Daocai fermentation. Food Chemistry-X, 24 (101827). [PMID:39421152] [10.1016/j.fochx.2024.101827] |
| 6. Wanli You, Si Chen, Jinglin Zhang, Xueyin Ru, Feng Xu, Zhengguo Wu, Peng Jin, Yonghua Zheng, Shifeng Cao. (2024) Effect of ultrasound pretreatment combined with different drying methods on the quality and bioactive compounds of broccoli stems. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, [10.1111/ijfs.17555] |
| 7. Minghui Xu, Xiaoru Yao, Yichen Wang, Haihan Liu, Wenjia Yang, Pingping Zhang. (2025) Electrospun miRNA-21@doxycycline core-sheath nanofibers for a synergistic treatment of diabetic wounds. COMPOSITES COMMUNICATIONS, 53 (102239). [10.1016/j.coco.2024.102239] |
| 8. Cong Li, Ruizeng Luo, Yuan Bai, Jiajia Shao, Jianying Ji, Engui Wang, Zhe Li, Hongyu Meng, Zhou Li. (2024) Molecular Doped Biodegradable Triboelectric Nanogenerator with Optimal Output Performance. ADVANCED FUNCTIONAL MATERIALS, (2400277). [10.1002/adfm.202400277] |
| 9. Nian Shi, Wenxuan Li, Yuwei Liu, Shumei Yan, Xia Xu, Di Chen. (2024) One-pot derivatization/magnetic solid-phase extraction combined with high-performance liquid chromatography-fluorescence detection for rapid analysis of biogenic amines in alcoholic beverages. FOOD CHEMISTRY, 460 (140754). [PMID:39121762] [10.1016/j.foodchem.2024.140754] |
| 10. Bi Guoshu, Liang Jiaqi, Bian Yunyi, Shan Guangyao, Huang Yiwei, Lu Tao, Zhang Huan, Jin Xing, Chen Zhencong, Zhao Mengnan, Fan Hong, Wang Qun, Gan Boyi, Zhan Cheng. (2024) Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer. Nature Communications, 15 (1): (1-20). [PMID:38504107] [10.1038/s41467-024-46776-w] |
| 11. Dan Feng, Jian Zhang, Huanmin Niu, Xiaoxue Zheng, Mengqi Jia, Qiqi Lu, Jing Wang, Wenxue Guo, Qi Sun, Huiqing Yuan, Hongxiang Lou. (2025) Spermidine inactivates proteasome activity and enhances ferroptosis in prostate cancer. Acta Pharmaceutica Sinica B, [10.1016/j.apsb.2025.02.023] |
| 12. Zhen Wu, Yi Wei, Yue Tang, Lian Xia, Xiaojuan Niu, Yuangen Wu. (2025) Switching off-on colorimetric sensor for rapid and selective detection of histamine in aquatic products based on Cu2+-mediated laccase-mimic activity of Mn3O4 nanoparticles. FOOD CONTROL, 170 (111056). [10.1016/j.foodcont.2024.111056] |
| 13. Haichao Ye, Liqin Liu, Dagang Shen, Chang Song, Huanhuan Wang. (2024) The Fluorescent Sensing of BF3 and Amines: A Dual Approach with Hydrazone Ligands. SENSORS, 24 (23): (7415). [PMID:39685952] [10.3390/s24237415] |
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