首页
400-620-6333
10篇引用文献 
计算溶液所需的质量、体积或浓度。
This is a demo store. No orders will be fulfilled.
磺胺胍
有货
库存信息
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| S424852-1ml |
1ml |
现货  |
|
切换导航
关闭
搜索
基本描述
| 别名 | 磺胺脒 |
|---|---|
| 英文别名 | ((p-Aminophenyl)sulfonyl)guanidine | KBioGR_000758 | Solfaguanidina [DCIT] | BSPBio_002951 | DTXCID103609 | Guanicil | N-(4-aminobenzenesulfonyl)guanidine | N(sup 1)-(Diaminomethylene)sulfanilamide | SCHEMBL93640 | S-Guanidine | 4-Aminobenzenesulfonylguanidine | Spectrum5_0011 |
| 规格或纯度 | Moligand™, 10mM in DMSO |
| 英文名称 | Sulfaguanidine |
| 储存温度 | 避光,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
1g溶于约1000ml25℃的水，溶于约10ml100℃水。微溶于乙醇或丙酮，易溶于稀盐酸。无臭，无味，遇光色渐变深。 |
关联靶点（人）
F2
Tclin
凝血酶原(Prothrombin)
(1 活性数据)
F2
Tclin
Thrombin
(11687 活性数据)
CA2
Tclin
Carbonic anhydrase II
(17698 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
HTR2B
Tclin
Serotonin 2b (5-HT2b) receptor
(10323 活性数据)
TBXA2R
Tclin
Thromboxane A2 receptor
(5717 活性数据)
PDE4A
Tclin
Phosphodiesterase 4A
(1943 活性数据)
ADORA3
Tchem
Adenosine A3 receptor
(15931 活性数据)
HRH3
Tclin
Histamine H3 receptor
(10389 活性数据)
KDR
Tclin
Vascular endothelial growth factor receptor 2
(20924 活性数据)
CA5A
Tclin
Carbonic anhydrase VA
(1168 活性数据)
CYP2D6
Tclin
Cytochrome P450 2D6
(33882 活性数据)
CYP1A2
Tchem
Cytochrome P450 1A2
(26471 活性数据)
CYP2C9
Tchem
Cytochrome P450 2C9
(32119 活性数据)
CYP2C19
Tchem
Cytochrome P450 2C19
(29246 活性数据)
CYP3A4
Tclin
Cytochrome P450 3A4
(53859 活性数据)
LMNA
Tbio
Prelamin-A/C
(36751 活性数据)
GMNN
Tbio
Geminin
(128009 活性数据)
SLCO1B1
Tchem
Solute carrier organic anion transporter family member 1B1
(2672 活性数据)
SLCO1B3
Tchem
Solute carrier organic anion transporter family member 1B3
(2517 活性数据)
关联靶点（其它种属）
ampC
Beta-lactamase AmpC (62480 活性数据)
Trypsin (394 活性数据)
Hdac6
Histone deacetylase 6 (222 活性数据)
folP
Dihydropteroate synthase (129 活性数据)
Klebsiella pneumoniae (43867 活性数据)
Pasteurella multocida (1166 活性数据)
Escherichia coli (133304 活性数据)
Salmonella enteritidis (727 活性数据)
Bacillus subtilis (32866 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| EC号 | 200-345-9 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 2-(4-aminophenyl)sulfonylguanidine |
| INCHI | 1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11) |
| InChi Key | BRBKOPJOKNSWSG-UHFFFAOYSA-N |
| Smiles | C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N |
| Isomeric SMILES | C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N |
| PubChem CID | 5324 |
| 分子量 | 214.24 |
| Beilstein号 | 5659891 |
| Reaxy-Rn | 747716 |
化学和物理性质
| 敏感性 | 对光敏感 |
|---|---|
| 熔点 | 190-193°C |
| 分子量 | 214.250 g/mol |
| XLogP3 | -0.700 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 2 |
| 精确质量Exact Mass | 214.052 Da |
| 单同位素质量Monoisotopic Mass | 214.052 Da |
| 拓扑极表面积Topological Polar Surface Area | 133.000 Ų |
| 重原子数Heavy Atom Count | 14 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 307.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
安全和危险性（GHS）
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| RTECS | WO8575000 |
| Merck Index | 8908 |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
此产品的引用文献
引用文献
| 1. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [10.3390/chemosensors11070386] |
| 2. Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. (2023) Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. ANALYTICAL CHEMISTRY, [PMID:37382204] [10.1021/acs.analchem.3c01928] |
| 3. Chen-Ting Zhu, Kai-Yuan Huang, Qing-Lin Zhou, Xiang-Ping Zhang, Gang-Wei Wu, Hua-Ping Peng, Hao-Hua Deng, Wei Chen, Hamada A.A. Noreldeen. (2023) Multi-excitation wavelength of gold nanocluster-based fluorescence sensor array for sulfonamides discrimination. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 288 (122138). [PMID:36442343] [10.1016/j.saa.2022.122138] |
| 4. Rongfang Yan, Zhenhua Wen, Xuelian Hu, Wenxiu Wang, He Meng, Yang Song, Shuo Wang, Yiwei Tang. (2023) A sensitive sensing system based on fluorescence dipeptide nanoparticles for sulfadimethoxine determination. FOOD CHEMISTRY, 405 (134963). [PMID:36413846] [10.1016/j.foodchem.2022.134963] |
| 5. Lixiang Zuo, Ran He, Li Wang, Yanli Wei. (2022) Phosphorescence aptasensing system for sulfadimethoxine with petal-like MoS2 nanosheets for signal amplification. SENSORS AND ACTUATORS B-CHEMICAL, 360 (131639). [10.1016/j.snb.2022.131639] |
| 6. X. Lu, M. Yu, D. Wang, P. Xiu, C. Xu, A.F. Lee, X. Gu. (2021) Flame-retardant effect of a functional DOPO-based compound on lignin-based epoxy resins. Materials Today Chemistry, 22 (100562). [10.1016/j.mtchem.2021.100562] |
| 7. Changjun Hu, Zhenkun Mao, Zhentao Li, Qiaoyan Li, Zilin Chen. (2021) Benzoic acid-modified monolithic column for separation of hydrophilic compounds by capillary electrochromatography with high content of water in mobile phase. JOURNAL OF CHROMATOGRAPHY A, 1647 (462166). [PMID:33957344] [10.1016/j.chroma.2021.462166] |
| 8. Peng Wang, Lei Chen, Hang Xiao, Tonghui Zhan. (2020) Nitrogen/sulfur-containing DOPO based oligomer for highly efficient flame-retardant epoxy resin. POLYMER DEGRADATION AND STABILITY, 171 (109023). [10.1016/j.polymdegradstab.2019.109023] |
| 9. Dandan Qin, Wangyang Lu, Xiyi Wang, Nan Li, Xia Chen, Zhexin Zhu, Wenxing Chen. (2016) Graphitic Carbon Nitride from Burial to Re-emergence on Polyethylene Terephthalate Nanofibers as an Easily Recycled Photocatalyst for Degrading Antibiotics under Solar Irradiation. ACS Applied Materials & Interfaces, 8 (39): (25962–25970). [PMID:27617344] [10.1021/acsami.6b07680] |
| 10. Zhen Yu, Yanlin Liu, Sheng Wang, Yajin Fang, Xiangyu Zhou, Zhaobin Tang, Jin Zhu, Junping Zhang. (2024) N-Sulfonyl Guanidine Urea to Design Ultrastrong, Stable, and Recyclable Associative Dynamic Polyurea Networks. MACROMOLECULES, 57 (23): (10938-10947). [10.1021/acs.macromol.4c01575] |