| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| S420418-1ml |
1ml |
现货  |
|
| 别名 | 红景天甙 |
|---|---|
| 英文别名 | 2-(4-Hydroxyphenyl)ethyl beta-D-glucopyranoside | SALIDROSIDE (USP-RS) | NCGC00256072-01 | Tox21_113565 | NCGC00257931-01 | A800725 | NSC 741643 | s2396 | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol | AKOS00 |
| 规格或纯度 | Moligand™, 10mM in DMSO |
| 英文名称 | Salidroside |
| 生化机理 | 皂苷是酪醇的 8-O-β-D-葡萄糖苷，是红景天的主要生物活性成分，主要存在于植物根部。它是在酪氨酸代谢过程中生物合成的，酪醇的葡萄糖基化是最后一步。据报道，它具有神经保护作用，是红景天抗抑郁和抗焦虑作用的主要成分之一。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
Natural product derived from plant source. Natural product derived from plant source. |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol |
| INCHI | 1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1 |
| InChi Key | ILRCGYURZSFMEG-RKQHYHRCSA-N |
| Smiles | C1=CC(=CC=C1CCOC2C(C(C(C(O2)CO)O)O)O)O |
| Isomeric SMILES | C1=CC(=CC=C1CCO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O |
| PubChem CID | 159278 |
| 分子量 | 300.31 |
| 分子量 | 300.300 g/mol |
|---|---|
| XLogP3 | -0.600 |
| 氢键供体数Hydrogen Bond Donor Count | 5 |
| 氢键受体数Hydrogen Bond Acceptor Count | 7 |
| 可旋转键计数Rotatable Bond Count | 5 |
| 精确质量Exact Mass | 300.121 Da |
| 单同位素质量Monoisotopic Mass | 300.121 Da |
| 拓扑极表面积Topological Polar Surface Area | 120.000 Ų |
| 重原子数Heavy Atom Count | 21 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 306.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 5 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H319: 引起严重眼睛刺激 |
| 预防措施声明 |
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 |
| 1. Fei Wang, Fan Yang, Jiawei Liu, Quan Bai. (2023) Studies on the retention mechanism of solutes in hydrophilic interaction chromatography using stoichiometric displacement theory II. HILIC/RPLC dual-retention mechanism of solutes in hydrophilic interaction chromatography over the entire range of water concentration in mobile phase. TALANTA, 265 (124858). [PMID:37385194] [10.1016/j.talanta.2023.124858] |
| 2. Qi Liang, Rongjie Guo, Jia-Ruei Tsao, Yun He, Chenchen Wang, Jiaxuan Jiang, Di Zhang, Taige Chen, Tingting Yue, Kai Hu. (2023) Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway. INTERNATIONAL IMMUNOPHARMACOLOGY, 121 (110397). [PMID:37302369] [10.1016/j.intimp.2023.110397] |
| 3. Yang Rongling, Wang Yu, Zhao Xiangjie, Tong Zheng, Zhu Qianlin, He Xiaoxi, Wang Zhaoyu, Luo Hongzhen, Fang Fang. (2022) A facile and efficient synthesis approach of salidroside esters by whole-cell biocatalysts in organic solvents. Frontiers in Bioengineering and Biotechnology, 10 [PMID:36507279] [10.3389/fbioe.2022.1051117] |
| 4. Jiaqi Li, Yongguang Zhang, Zhimin Yang, Jingxian Zhang, Ren Lin, Daoshu Luo. (2020) Salidroside promotes sciatic nerve regeneration following combined application epimysium conduit and Schwann cells in rats. EXPERIMENTAL BIOLOGY AND MEDICINE, [PMID:32053008] [10.1177/1535370220906541] |
| 5. Xiaojing SI, Chaolin WANG, Li LI, Daixin YE, Youli WEI, Yaping DING. (2020) Preparation of nickel-aluminum hydrotalcite nanosheet-coated carbon nanofibers and their application in the detection of salidroside. MICROCHEMICAL JOURNAL, 155 (104652). [10.1016/j.microc.2020.104652] |
| 6. Shasha Chen, Feng Cai, Jirong Wang, Zhouxin Yang, Chi Gu, Guofu Wang, Genxiang Mao, Jing Yan. (2019) Salidroside protects SH‑SY5Y from pathogenic α‑synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling. Molecular Medicine Reports, 20 (1): (529-538). [PMID:31180515] [10.3892/mmr.2019.10285] |
| 7. Jiahong Han, Min Dai, Yan Zhao, Enbo Cai, Lianxue Zhang, Xiaohuan Jia, Nian Sun, Xuan Fei, Hui Shu. (2020) Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis. Journal of Ginseng Research, 44 (291). [PMID:32148411] [10.1016/j.jgr.2019.01.001] |
| 8. Zhou Fei, Zhao Yajing, Li Maiquan, Xu Tao, Zhang Liuquan, Lu Baiyi, Wu Xiaodan, Ge Zhiwei. (2017) Degradation of phenylethanoid glycosides in Osmanthus fragrans Lour. flowers and its effect on anti-hypoxia activity. Scientific Reports, 7 (1): (1-10). [PMID:28855701] [10.1038/s41598-017-10411-0] |
| 9. Zhilin Qi, Shimei Qi, Liefeng Ling, Jun Lv, Zunyong Feng. (2016) Salidroside attenuates inflammatory response via suppressing JAK2-STAT3 pathway activation and preventing STAT3 transfer into nucleus. INTERNATIONAL IMMUNOPHARMACOLOGY, 35 (265). [PMID:27085677] [10.1016/j.intimp.2016.04.004] |
| 10. Yanfen Bai, Hua Yin, Huiping Bi, Yibin Zhuang, Tao Liu, Yanhe Ma. (2016) De novo biosynthesis of Gastrodin in Escherichia coli. METABOLIC ENGINEERING, 35 (138). [PMID:26804288] [10.1016/j.ymben.2016.01.002] |
| 11. Yibo Feng, Xiaojuan Zhao, Fang Lv, Jinqiu Zhang, Bihua Deng, Yanhong Zhao, Yuanliang Hu, Deyun Wang, Jiaguo Liu, Yu Lu, Ruonan Bo, Zhenguang Liu. (2015) Optimization on Preparation Conditions of Salidroside Liposome and Its Immunological Activity on PCV-2 in Mice. Evidence-based Complementary and Alternative Medicine, 2015 (178128). [PMID:25878712] [10.1155/2015/178128] |
| 12. Lingyun Xiao, Haifeng Li, Ju Zhang, Fan Yang, Aizhen Huang, Jingjing Deng, Ming Liang, Fangli Ma, Minghua Hu, Zebo Huang. (2014) Salidroside Protects Caenorhabditis elegans Neurons from Polyglutamine-Mediated Toxicity by Reducing Oxidative Stress. MOLECULES, 19 (6): (7757-7769). [PMID:24918543] [10.3390/molecules19067757] |
| 13. Yanhong Bi, Ruiping Fu, Weiliang Hua, Xinyu Xiong, Chun Zhu, Xiaobao Nie, Zhaoyu Wang. (2025) An empirical exploration of the capacity of choline chloride/lactic acid eutectics to extract and stabilize natural polyhydroxy compounds. FOOD CHEMISTRY, (143873). [PMID:40120314] [10.1016/j.foodchem.2025.143873] |
| 14. Zhibin Zhou, Mengzhen Zhao, Huaqiang Fang, Ziyue Lin, Xinrui Zheng, Yi Zhuo, Zimeng Li, Weiming Zhou, Xiaolei Wang. (2024) Conductive hydrogel with responsive release of Herbal-Derived carbon dots for neurovascular reconstruction in diabetic critical limb ischemia. CHEMICAL ENGINEERING JOURNAL, 500 (157265). [10.1016/j.cej.2024.157265] |
| 15. Jishan Li, Muyang Li, Chenyu Yong, Zhemin Zhou, Laichuang Han, Zhongmei Liu. (2025) Reshaping UDP-binding pocket of bacterial sucrose synthase to improve efficiency of UDP-glucose production. BIORESOURCE TECHNOLOGY, 427 (132396). [PMID:40090494] [10.1016/j.biortech.2025.132396] |
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