基本描述

别名	(R)-2-羟基丙酸
英文别名	(D)-(-)-Lactic acid \| (R)-lactate \| (R)-2-Hydroxypropionate \| D-2-Hydroxypropionic acid \| D-(-)-Lactate \| D-LACTIC ACID [WHO-DD] \| AS-19478 \| HY-111095 \| (R)-2-Hydroxypropionic acid(R)-2-Hydroxypropionic acid \| (R)-alpha-Hydroxypropionate \| D-Lactic acid
规格或纯度	Moligand™, ≥90%(T)
英文名称	D-Lactic Acid
生化机理	在动物体内，乳酸是细胞增殖和在剧烈运动等无氧条件下产生的一种代谢化合物。乳酸可被氧化回丙酮酸或通过葡萄糖生成转化为葡萄糖。在几种哺乳动物和大脑早期发育过程中，神经元优先代谢乳酸。D 型乳酸的利用速度是 L 型乳酸的四倍，但这两种异构体在肠道中的吸收速度相同。
储存温度	-20°C储存
运输条件	超低温冰袋运输
作用类型	激动剂
作用机制	HCA 1 受体激动剂
产品介绍	Lactic acid is used as a reagent in organic synthesis (in the manufacture of adhesives). It is used in the leather, textile, and tanning industries. It may be used as a plasticizer, a catalyst, or an acidifying agent. Lactic acid has even been used as a flavoring agent in the manufacture of tobacco products. Lactic acid is used as a reagent in organic synthesis (in the manufacture of adhesives). It is used in the leather, textile, and tanning industries. It may be used as a plasticizer, a catalyst, or an acidifying agent. Lactic acid has even been used as a flavoring agent in the manufacture of tobacco products.
纯度	≥90%(T)

关联靶点（人）

HCAR1 Tchem 羟基羧酸受体1(Hydroxycarboxylic acid receptor 1) (1 活性数据)

点击查看靶蛋白信息： HCAR1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

SLC16A1 Tchem Monocarboxylate transporter 1 (146 活性数据)

点击查看靶蛋白信息： SLC16A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 活性数据)

点击查看靶蛋白信息： SLCO2B1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC16A3 Tchem Monocarboxylate transporter 4 (196 活性数据)

点击查看靶蛋白信息： SLC16A3

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC16A7 Tchem Monocarboxylate transporter 2 (11 活性数据)

点击查看靶蛋白信息： SLC16A7

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC16A10 SLC16A10 protein (28 活性数据)

点击查看靶蛋白信息： SLC16A10

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Slco2a1 Solute carrier organic anion transporter family member 2A1 (47 活性数据)

点击查看靶蛋白信息： Slco2a1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Slc16a10 Monocarboxylate transporter 10 (73 活性数据)

点击查看靶蛋白信息： Slc16a10

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

分子类型	小分子
IIUPAC Name	(2R)-2-hydroxypropanoic acid
INCHI	1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1
InChi Key	JVTAAEKCZFNVCJ-UWTATZPHSA-N
Smiles	CC(C(=O)O)O
Isomeric SMILES	C[C@H](C(=O)O)O
分子量	90.08
Reaxy-Rn	1209341
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209341&ln=

化学和物理性质

溶解性	Soluble in water (50mg/ml)
密度	1.21
敏感性	对热敏感
折光率	1.43
比旋光度	13° (C=2.5,1.5mol/L NaOH)
闪点(℃)	110 °C
分子量	90.080 g/mol
XLogP3	-0.700
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	90.0317 Da
单同位素质量Monoisotopic Mass	90.0317 Da
拓扑极表面积Topological Polar Surface Area	57.500 Å²
重原子数Heavy Atom Count	6
形式电荷Formal Charge	0
复杂度Complexity	59.100
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS05, GHS07
信号词	危险
危险声明	H315: 引起皮肤刺激 H318: 造成严重的眼睛损伤
预防措施声明	P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
Merck Index	5335

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到19个结果

批号(Lot Number)	证书类型	货号
E2520399	分析证书	S161106
E2520400	分析证书	S161106
E2520401	分析证书	S161106
E2520548	分析证书	S161106
E2520549	分析证书	S161106
I2516040	分析证书	S161106
E2112285	分析证书	S161106
F2404014	分析证书	S161106
A2510637	分析证书	S161106
C2514184	分析证书	S161106
G2326283	分析证书	S161106
G2326562	分析证书	S161106
G2326585	分析证书	S161106
G2326589	分析证书	S161106
G2326594	分析证书	S161106
G2213380	分析证书	S161106
G2213382	分析证书	S161106
G2213383	分析证书	S161106
F2307328	分析证书	S161106

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引用文献

1. Rongxiu Qin, Haiyan Chen, Rusi Wen, Guiqing Li, Zhonglei Meng. (2023) Effect of Boric Acid on the Ionization Equilibrium of α-Hydroxy Carboxylic Acids and the Study of Its Applications. MOLECULES, 28 (12): (4723). [PMID:37375278] [10.3390/molecules28124723]
2. Xiao Zheng, Ying Liu, Yiqiong Liu, Tingting Zhang, Yuge Zhao, Jie Zang, Yan Yang, Ruiqing He, Gaowei Chong, Shuangrong Ruan, Dailin Xu, Yongyong Li, Haiqing Dong. (2022) Dual Closed-Loop of Catalyzed Lactate Depletion and Immune Response to Potentiate Photothermal Immunotherapy. ACS Applied Materials & Interfaces, 14 (20): (23260–23276). [PMID:35578899] [10.1021/acsami.2c07254]
3. Jie Sun, Yaping Wang, Zhenguo Gao, Junbo Gong, Weiwei Tang. (2022) Additive-assisted preferential crystallization of racemic component: A case of norvaline. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 110 (206). [10.1016/j.jiec.2022.02.054]
4. Jianjian Zhao, Aiyou Hao, Pengyao Xing. (2021) Enhancing Optical Activities of Benzimidazole Derivatives through Coassembly for High-Efficiency Synthesis of Chiroptical Nanomaterials and Accurate ee % Detection of Natural Acids. ACS Applied Materials & Interfaces, 13 (5): (6830–6843). [PMID:33502861] [10.1021/acsami.0c20735]
5. Kaiyang Ma, Xiao Ding, Qiqi Song, Zhitao Han, Hang Yao, Jianhua Ding, Gang Hu. (2020) Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes. NEUROPHARMACOLOGY, 171 (108084). [PMID:32294462] [10.1016/j.neuropharm.2020.108084]
6. Shengli Mi, Jingjing Xia, Yuanyuan Xu, Zhichang Du, Wei Sun. (2019) An integrated microchannel biosensor platform to analyse low density lactate metabolism in HepG2 cells in vitro. RSC Advances, 9 (16): (9006-9013). [PMID:35517697] [10.1039/C9RA00694J]
7. Ai-Ling Hu, Yin-Huan Liu, Hao-Hua Deng, Guo-Lin Hong, Ai-Lin Liu, Xin-Hua Lin, Xing-Hua Xia, Wei Chen. (2014) Fluorescent hydrogen peroxide sensor based on cupric oxide nanoparticles and its application for glucose and l-lactate detection. BIOSENSORS & BIOELECTRONICS, 61 (374). [PMID:24912038] [10.1016/j.bios.2014.05.048]
8. Chen Chen, Ziwei Liu, Jianzheng Li, Davide Vurro, Yizhou Jiang, Luyu Xue, Ye Gong, Yaje Qin. (2024) A Miniaturized Flexible Patch Based on CNT Fiber Sensors and Highly Integrated SoC for Analysis of Sweat. IEEE SENSORS JOURNAL, 24 (22): (1-1). [10.1109/JSEN.2024.3465048]
9. Qing Li, Congnan Wu, Jiaxing Zhang, Rongxin Su, Yuefei Wang, Wei Qi. (2024) Construction of chiral nanozymes with high enantioselectivity for visual detection via smartphone-based paper sensors. CHEMICAL ENGINEERING JOURNAL, 495 (153326). [10.1016/j.cej.2024.153326]
10. Xinwen Jia, Mengyun Lu, Wenjing Zhang, Wuduo Zhao, Ajuan Yu, Shusheng Zhang. (2025) Fluorescence enantioselective sensing of lactic acid enantiomers by Zn-MOC@CQDs with double chiral building blocks. MICROCHEMICAL JOURNAL, 208 (112575). [10.1016/j.microc.2024.112575]
11. Jing Zhang, Zishuo Fang, Heng Dong, Yu Liu, Zhenyu Chu, Yongbin Mou, Wanqin Jin. (2024) MnFe@N-CNTs Based Lactate Biomicrochips for Nonintrusive and Onsite Periodontitis Diagnosis. ACS Applied Materials & Interfaces, 16 (16): (20221-20231). [PMID:38593051] [10.1021/acsami.4c00979]
12. Ling Ding, Lou Gao, Di Pan, Ke Du, Jiayu Yu, Wanyi Li, Yahong Zhang, Yi Tang. (2024) Reducing meso-lactide formation from racemic lactic acid using shape-selective H-Beta zeolite. Catalysis Science & Technology, [10.1039/D4CY01046A]

溶液计算器

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货号 (SKU)	包装规格	是否现货
S161106-5g	5g	现货
S161106-25g	25g	现货
S161106-100g	100g	现货
S161106-500g	500g	现货
S161106-2.5kg	2.5kg	现货

D-乳酸, HCA 1 受体激动剂

库存信息

库存信息

库存信息

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库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

显示更多⌵

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器