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精胺, CaS 受体激动剂;K ir2.1 通道阻断剂;K ir2.3 通道阻断剂;维甲酸受体-α 激动剂;维甲酸受体-β 激动剂;维甲酸受体-γ 激动剂;TRPM4 通道阻断剂;TRPM5 通道阻断剂;TRPM7 通道阻断剂

61篇引用文献 COA COA
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货号 (SKU) 包装规格 是否现货 价格 数量
S113079-200mg
 200mg 期货 Stock Image
S113079-1g
 1g 现货 Stock Image
S113079-5g
 5g 期货 Stock Image
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Anti-infection (2804) Endogenous Metabolite (978) Influenza Virus (253) Metabolic Enzyme/Protease (4889) PROTAC linker (725) Retinoic acid receptor-α Agonist (11) Retinoic acid receptor-β Agonist (12) Retinoic acid receptor-γ Agonist (12) Virus (3767) 代谢物 (8911) 荧光试剂 (168)
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基本描述

别名 精素
英文别名 AS-35114 | n1,n1'-(butane-1,4-diyl)dipropane-1,3-diamine | 2FZ7Y3VOQX | BPBio1_001086 | SMR001397086 | 1,4-Bis(aminopropyl)butanediamine | N,Na?Bis(3-aminopropyl)-1,4-diaminobutane | Q424597 | HB0588 | N,N''-bis(3-aminopropyl)butane-1,4-diamine | N,N'-Bis
规格或纯度 Moligand™, 用于细胞培养, ≥98%(GC)
英文名称 Spermine
应用 混合NMDA谷氨酸受体在多胺位点上的激动剂/拮抗剂。在高浓度(1 mM)时已被观察到具神经保护作用，而在低浓度时，可观察到具有神经毒性。它增强了在马钱子碱不敏感的甘氨酸位点的反作用。对细胞增殖和分化起主要作用;抑制神经元一氧化氮合成酶（nNOS）。 精胺、腐胺及亚精胺组成了多胺家族（polycations，聚阳离子），这对于绝大多数的活细胞生长和生存是必需的。多胺与带负电荷的分子相互作用，如蛋白多糖(proteoglycans)，糖化蛋白(glycated proteins)和核酸（DNA和RNA）。生物多胺被发现在不同层次可调控蛋白合成。这种影响可被解释为多胺结合和影响tRNA，mRNA和rRNA的二级结构。精胺也有助于稳定核酸螺旋结构并组成糖化蛋白如组蛋白（the histones）。精胺和亚精胺是各种核酸转染方案的组件。
储存温度 2-8°C储存
运输条件 冰袋运输
作用类型 激动剂
作用机制 CaS 受体激动剂;K ir2.1 通道阻断剂;K ir2.3 通道阻断剂;维甲酸受体-α 激动剂;维甲酸受体-β 激动剂;维甲酸受体-γ 激动剂;TRPM4 通道阻断剂;TRPM5 通道阻断剂;TRPM7 通道阻断剂
产品介绍

Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth and is involved in the modulation of calcium-dependent immune processes. Spermine inhibits NOS1 (nNOS). Spermine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner. Spermine is a GluR inhibitor.混合NMDA谷氨酸受体在多胺位点上的激动剂/拮抗剂。在高浓度(1 mM)时已被观察到具神经保护作用，而在低浓度时，可观察到具有神经毒性。它增强了在马钱子碱不敏感的甘氨酸位点的反作用。对细胞增殖和分化起主要作用;抑制神经元一氧化氮合成酶（nNOS）。 精胺、腐胺及亚精胺组成了多胺家族（polycations，聚阳离子），这对于绝大多数的活细胞生长和生存是必需的。多胺与带负电荷的分子相互作用，如蛋白多糖(proteoglycans)，糖化蛋白(glycated proteins)和核酸（DNA和RNA）。生物多胺被发现在不同层次可调控蛋白合成。这种影响可被解释为多胺结合和影响tRNA，mRNA和rRNA的二级结构。精胺也有助于稳定核酸螺旋结构并组成糖化蛋白如组蛋白（the histones）。精胺和亚精胺是各种核酸转染方案的组件。

Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth and is involved in the modulation of calcium-dependent immune processes. Spermine inhibits NOS1 (nNOS). Spermine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner. Spermine is a GluR inhibitor.
A NOS1 inhibitor, NMDA activator, and GluR inhibitor.
纯度 ≥98%(GC)

关联靶点（人）

CA5A Tclin 碳酸酐酶 5A，线粒体(Carbonic anhydrase 5A, mitochondrial) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
RARG Tclin 视黄酸受体γ(Retinoic acid receptor gamma) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TRPM4 Tchem 瞬时受体电位阳离子通道亚家族M成员4(Transient receptor potential cation channel subfamily M member 4) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TRPM5 Tchem 瞬时受体电位阳离子通道亚家族M成员5(Transient receptor potential cation channel subfamily M member 5) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TRPM7 Tchem 瞬时受体电位阳离子通道亚家族 M 成员 7(Transient receptor potential cation channel subfamily M member 7) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
KCNJ4 Tchem 内向整流钾通道4(Inward rectifier potassium channel 4) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
KCNJ2 Tchem 内向整流钾通道2(Inward rectifier potassium channel 2) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
RARB Tclin 视黄酸受体β(Retinoic acid receptor beta) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
RARA Tclin 视黄酸受体α(Retinoic acid receptor alpha) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA5B Tclin 碳酸酐酶 5B，线粒体(Carbonic anhydrase 5B, mitochondrial) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA6 Tclin 碳酸酐酶6(Carbonic anhydrase 6) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CASR Tclin 细胞外钙敏感受体(Extracellular calcium-sensing receptor) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA4 Tclin 碳酸酐酶4(Carbonic anhydrase 4) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA14 Tclin 碳酸酐酶14(Carbonic anhydrase 14) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA7 Tclin 碳酸酐酶7(Carbonic anhydrase 7) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GRIN2B Tclin Glutamate [NMDA] receptor subunit epsilon 2 (467 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ODC1 Tclin Ornithine decarboxylase (70 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CASP3 Tchem Caspase-3 (3632 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA3 Tclin Carbonic anhydrase III (753 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA6 Tclin Carbonic anhydrase VI (993 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CASP2 Tchem Caspase-2 (173 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PAOX Tchem Polyamine oxidase (84 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CXCR4 Tclin C-X-C chemokine receptor type 4 (3338 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA5B Tclin Carbonic anhydrase VB (957 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TERT Tchem Telomerase reverse transcriptase (2428 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Homo sapiens (32628 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DU-145 (51482 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Huh-7 (12904 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
K562 (73714 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
U-251 (51189 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
U-937 (7138 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ZR-75-1 (953 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
T47D (39041 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HeLa (62764 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
F13A1 Tchem Coagulation factor XIII (223 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC22A1 Tchem Solute carrier family 22 member 1 (646 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
THPO Tbio Thrombopoietin (834 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GRIN1 Tclin Glutamate NMDA receptor; GRIN1/GRIN2A (719 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Ca7 Carbonic anhydrase VII (3 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Sat1 Spermidine/spermine N(1)-acetyltransferase 1 (20 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ca13 Carbonic anhydrase XIII (322 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA4 Carbonic anhydrase IV (1713 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AOC3 Amine oxidase, copper containing (44 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Salmonella typhimurium (15756 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHO (4503 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHO-MG (239 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L1210 (27553 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P19 (309 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SV3T3 (134 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Calf thymus DNA (4845 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ca15 Carbonic anhydrase 15 (173 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Drosophila (190 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Slc22a4 Solute carrier family 22 member 4 (11 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TUBB2B Tubulin (2175 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Grin1 Glutamate NMDA receptor; Grin1/Grin2b (1028 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Lipopolysaccharide (LPS) (376 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 200-754-2
分子类型 小分子
IIUPAC Name N,N'-bis(3-aminopropyl)butane-1,4-diamine
INCHI 1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2
InChi Key PFNFFQXMRSDOHW-UHFFFAOYSA-N
Smiles C(CCNCCCN)CNCCCN
Isomeric SMILES C(CCNCCCN)CNCCCN
PubChem CID 1103
UN Number 3259
分子量 202.34
Beilstein号 1750791

化学和物理性质

溶解性 Soluble in chloroform, methanol, water, and lower alcohols. Insoluble in ether, benzene, and petroleum ether.
敏感性 对湿度和空气敏感
闪点(℉) 110 °C
闪点(℃) 110°C
沸点 150 °C/5 mmHg
熔点 28-30°C
分子量 202.340 g/mol
XLogP3 -1.100
氢键供体数Hydrogen Bond Donor Count 4
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 11
精确质量Exact Mass 202.216 Da
单同位素质量Monoisotopic Mass 202.216 Da
拓扑极表面积Topological Polar Surface Area 76.100 Ų
重原子数Heavy Atom Count 14
形式电荷Formal Charge 0
复杂度Complexity 86.100
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS05
信号词 危险
危险声明

H226: 易燃液体和蒸气

H304: 吞咽并进入呼吸道可能致命

H315: 引起皮肤刺激

H317: 可能引起皮肤过敏反应

H319: 引起严重眼睛刺激

H411: 对水生生物有毒并具有长期持续影响
预防措施声明

P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。

P233: 保持容器密闭。

P240: 地面/粘结容器和接收设备

P241: 使用防爆的[电气/通风/照明/.../]设备。

P242: 仅使用无火花的工具。

P243: 采取防静电措施

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P272: 被污染的工作服不允许离开工作场所

P273: 避免释放到环境中。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P331: 不要催吐

P391: 收集溢出物

P302+P352: 如皮肤沾染：用水充分清洗。

P303+P361+P353: 如皮肤（或头发）沾染：立即脱掉所有沾染的衣服。用水清洗皮肤/淋浴。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

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引用文献

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9. Nuo Duan, Kexin Ren, Mingqian Song, Xinyue Zhang, Zhouping Wang, Fei Jia, Shijia Wu.  (2023)  A dual-donor FRET based aptamer sensor for simultaneous determination of histamine and tyramine in fishes.  MICROCHEMICAL JOURNAL,  191  (108801).  [10.1016/j.microc.2023.108801]
10. Si Lin, Hou Juying, Lv Wei, Hou Qin, Xu Zhixiang, Ai Shiyun.  (2023)  An intelligent fluorescence platform based on lignocellulose components and fluorescein for food freshness monitoring.  Biomass Conversion and Biorefinery,  (1-11).  [10.1007/s13399-023-03879-6]
11. Wenyang Zhang, Da-Wen Sun, Ji Ma, Anjun Qin, Ben Zhong Tang.  (2023)  A ratiometric fluorescent tag based on dual-emissive hydrophobic carbon dots for in-situ monitoring of seafood freshness.  ANALYTICA CHIMICA ACTA,  1250  (340931).  [PMID:36898807] [10.1016/j.aca.2023.340931]
12. Wang Tingting, Chen Yihui, Hou Chunyan, Qiao Xiaoqiang.  (2023)  PEG-modified halloysite as a hydrophilic interaction and cation exchange mixed-mode sorbent for solid-phase extraction of biogenic amines in fish samples.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (18): (4265-4275).  [PMID:36422664] [10.1007/s00216-022-04441-5]
13. Guoqing Wang, Xinyue Meng, Peiyan Wang, Xinping Wang, Gaoli Liu, Dong-An Wang, Changjiang Fan.  (2022)  A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries.  BIOMATERIALS,  291  (121908).  [PMID:36384085] [10.1016/j.biomaterials.2022.121908]
14. Yuan-Fu Ding, Jianwen Wei, Xingping Quan, Wenting Gu, Long Xi, Ying Zheng, Yonghua Zhao, Jingwei Luo, Shengke Li, Greta S.P. Mok, Ruibing Wang.  (2022)  Hyaluronic acid-based supramolecular medicine with polyamines sequestration capability for cooperative anti-psoriasis.  CARBOHYDRATE POLYMERS,  296  (119968).  [PMID:36088007] [10.1016/j.carbpol.2022.119968]
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16. Liu Dehong, Shi Hongjie, Chen Guanglin, Zhang Xu, Gu Tingyue, Zhu Minglong, Tan Wensong.  (2022)  Strategies for anti-oxidative stress and anti-acid stress in bioleaching of LiCoO2 using an acidophilic microbial consortium.  EXTREMOPHILES,  26  (2): (1-16).  [PMID:35767155] [10.1007/s00792-022-01270-3]
17. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang, Bin Di, Chi Hu.  (2022)  Teaching PCR for Simultaneous Sensing of Gene Transcription and Downstream Metabolites by Cucurbit[8]uril-Mediated Intervention of Polymerase Activity.  ANALYTICAL CHEMISTRY,  94  (24): (8715–8723).  [PMID:35671188] [10.1021/acs.analchem.2c01103]
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19. Qianqian Zhang, Jianwei Bao, Tijie Duan, Minxing Hu, Yuting He, Junwei Wang, Rongfeng Hu, Jihui Tang.  (2022)  Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer.  Pharmaceutics,  14  (3): (510).  [PMID:35335884] [10.3390/pharmaceutics14030510]
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22. Yongliang Guo, Lili Tian, Jiangming Wu, Yang Wu, Yongmei Liu, Jie Du, Xiaoquan Lu.  (2021)  A Highly Sensitive Electrochemiluminescence Spermine Biosensor Based on Au−Ag Bimetallic Nanoclusters.  ELECTROANALYSIS,  33  (9): (2016-2024).  [10.1002/elan.202100169]
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25. Xin Li, Xiao-wen Jiang, Hai-xiao Chu, Qing-chun Zhao, Huai-wei Ding, Chao-hong Cai.  (2021)  Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.  Chinese Herbal Medicines,  13  (105).  [PMID:36117765] [10.1016/j.chmed.2020.12.004]
26. Yi-Fang Li, Zheng-Zhong Lin, Cheng-Yi Hong, Zhi-Yong Huang.  (2021)  Histamine detection in fish samples based on indirect competitive ELISA method using iron-cobalt co-doped carbon dots labeled histamine antibody.  FOOD CHEMISTRY,  345  (128812).  [PMID:33601655] [10.1016/j.foodchem.2020.128812]
27. Tan Xiao-Hui, Li Yu-Bin, Liao Yan, Liu Hua-Zhong.  (2020)  An enzyme free fluorescence resonance transfer strategy based on hybrid chain reaction and triplex DNA for Vibrio parahaemolyticus.  Scientific Reports,  10  (1): (1-8).  [PMID:33244061] [10.1038/s41598-020-77913-2]
28. Zhongjuan Wang, Yueqin Liang, Yanqiu Liu, Hongying Xia, Jianqi Liu, Xingfang Jin, Zhongkun Li.  (2020)  The pH-triggered polyglutamate brush co-delivery of MDR1 and survivin-targeting siRNAs efficiently overcomes multi-drug resistance of NSCLC.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY,  [PMID:32924641] [10.1080/03639045.2020.1822860]
29. Yan Zhou, Jia Liu, Tingting Zheng, Yang Tian.  (2020)  Label-Free SERS Strategy for In Situ Monitoring and Real-Time Imaging of Aβ Aggregation Process in Live Neurons and Brain Tissues.  ANALYTICAL CHEMISTRY,  92  (8): (5910–5920).  [PMID:32227892] [10.1021/acs.analchem.9b05837]
30. Hailong Sun, Shuangping Liu, Jieqi Mao, Ziwei Yu, Zhijie Lin, Jian Mao.  (2020)  New insights into the impacts of huangjiu compontents on intoxication.  FOOD CHEMISTRY,  317  (126420).  [PMID:32101783] [10.1016/j.foodchem.2020.126420]
31. Huili Tian, Nuo Duan, Shijia Wu, Zhouping Wang.  (2019)  Selection and application of ssDNA aptamers against spermine based on Capture-SELEX.  ANALYTICA CHIMICA ACTA,  1081  (168).  [PMID:31446954] [10.1016/j.aca.2019.07.031]
32. Xiaoguang Ying, Anshun Kang, Xiaomei Zhu, Xiao Li.  (2019)  Molecular imprint enhanced specific adsorption visualization on electrospun chromogenic membrane for efficient detection of putrescine.  JOURNAL OF APPLIED POLYMER SCIENCE,  136  (45): (48186).  [10.1002/app.48186]
33. Ruidi Shen, Li Zou, Shixin Wu, Tingting Li, Jing Wang, Jianmin Liu, Liansheng Ling.  (2019)  A novel label-free fluorescent detection of histidine based upon Cu2+-specific DNAzyme and hybridization chain reaction.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  213  (42).  [PMID:30682646] [10.1016/j.saa.2019.01.062]
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37. Wang Hongwei, Li Xiaoxi, Chen Ling, Huang Xiaoyi, Li Lin.  (2017)  Cationic starch/pDNA nanocomplexes assembly and their nanostructure changes on gene transfection efficiency.  Scientific Reports,  7  (1): (1-12).  [PMID:29093552] [10.1038/s41598-017-14551-1]
38. Yonghui Nie, Yuanjie Teng, Pan Li, Wenhan Liu, Qianwei Shi, Yuchao Zhang.  (2018)  Label-free aptamer-based sensor for specific detection of malathion residues by surface-enhanced Raman scattering.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  191  (271).  [PMID:29045930] [10.1016/j.saa.2017.10.030]
39. Xin Ji, Huilong Guo, Qiao Tang, Dong Ma, Wei Xue.  (2017)  A targeted nanocarrier based on polyspermine for the effective delivery of methotrexate in nasopharyngeal carcinoma.  Materials Science & Engineering C-Materials for Biological Applications,  81  (48).  [PMID:28888001] [10.1016/j.msec.2017.07.036]
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