Recombinant Human Tie-2 Protein

COA

级别和纯度:

无动物源

无载体

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: Q02763
蛋白标签: C-His
生物活性: Testing in progress
内毒素水平: <1.0 EU/μg

有货

库存信息

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货号 (SKU)	包装规格	是否现货
rp179792-10μg	10μg	现货
rp179792-50μg	50μg	现货
rp179792-100μg	100μg	现货
rp179792-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: TEK

Accession#: Q02763 (2) Gene ID: 7010 (2) TEK (2) Tie-2 (1) TIE2 (2)

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基本描述

产品名称	Recombinant Human Tie-2 Protein
别名	重组人Tie-2蛋白 \| 重组人类Tie-2蛋白
英文别名	CD202b antigen \| CD202b \| EC 2.7.10 \| EC 2.7.10.1 \| hTIE2 \| p140 TEK \| soluble TIE2 variant 1 \| soluble TIE2 variant 2 \| TEK tyrosine kinase, endothelial \| TEK \| Tie2 \| Tie-2 \| TIE2CD202b \| angiopoietin-1 receptor \| Tunica interna endothelial cell kinase
规格或纯度	Animal Free, Carrier Free, ≥95%(SDS-PAGE)
产品介绍	Protein Function: Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human Tie-2 cDNA encodes a 1124 amino acid (aa) precursor protein with an 18 aa putative signal peptide, a 727 aa extracellular domain (ECD) and a 354 aa cytoplasmic domain. Human Tie-2 ECD shares 90% aa identity with mouse and rat Tie-2. Two ligands, angiopoietin1 (Ang1) and angiopoietin2 (Ang2), which bind Tie-2 with high affinity, have been identified. Ang2 has been reported to act as an antagonist for Ang1. Mice engineered to over-express Ang2 or to lack Ang1 or Tie-2 display similar angiogenesis defects.
生物活性	Testing in progress
内毒素水平	<1.0 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	1-745 aa
序列	MDSLASLVLCGVSLLLSGTVEGAMDLILINSLPLVSDAETSLTCIASGWRPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNHLCTACMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPDPYGCSCATGWKGLQCNEACHPGFYGPDCKLRCSCNNGEMCDRFQGCLCSPGWQGLQCEREGIPRMTPKIVDLPDHIEVNSGKFNPICKASGWPLPTNEEMTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPKPLNAPNVIDTGHNFAVINISSEPYFGDGPIKSKKLLYKPVNHYEAWQHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATIIQYQLKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKHHHHHH
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	Q02763
来源	重组表达
预测分子量	81.4 kDa
SDS-PAGE	101.3 kDa, under reducing conditions; 99.4 kDa, under non-reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, pH 7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

SDS-PAGE: Recombinant Human Tie-2 Protein (rp179792)

Recombinant Human Tie-2 Protein (rp179792) - SDS-PAGE
3 μg/lane of Recombinant Human Tie-2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 101.3 kDa under reducing conditions and 99.4 kDa under non-reducing conditions.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0707688	分析证书	rp179792
ZJ24F0707686	分析证书	rp179792
ZJ24F0707687	分析证书	rp179792

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