Recombinant Human CD7 Protein

COA

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: P09564
蛋白标签: C-His
生物活性: Immobilized Recombinant Human CD7 protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.
内毒素水平: <1.0 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp176728-10μg	10μg	现货
rp176728-50μg	50μg	现货
rp176728-100μg	100μg	现货
rp176728-1mg	1mg	现货

查看相关系列

点击查看蛋白信息: CD7

Accession#:P09564 (17) CD7 (27) Gene ID:924 (17)

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基本描述

产品名称	Recombinant Human CD7 Protein
别名	重组人CD7蛋白 \| 重组人 CD7 蛋白
英文别名	CD7 antigen \| CD7 \| CD7 antigen (p41) \| CD7 molecule \| CD7_HUMAN \| GP40 \| LEU 9 \| LEU9 \| p41 protein \| T cell antigen CD7 \| T cell leukemia antigen \| T cell surface antigen Leu 9 \| T-cell antigen CD7 \| T-cell leukemia antigen \| T-cell surface antigen Leu-
规格或纯度	ActiBioPure™, 生物活性, 无动物源, Carrier Free, ≥95%(SDS-PAGE)
产品介绍	CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily. Mature human CD7 consists of a 155 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 39 aa cytoplasmic domain. Within the ECD, human CD7 shares 43% and 41% aa sequence identity with mouse and rat CD7, respectively. CD7 is expressed on T cells, NK cells, myeloid progenitor cells, and CD19+ B progenitor cells. Among CD8+ T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 associates in cis with CD3 and CD45 and in trans with SECTM1. Ligation of CD7 with antibodies or SECTM1 co‑stimulates the activation and proliferation of CD4+ and CD8+ T cells and NK cells. It also enhances integrin-mediated adhesion of these cells to Fibronectin, ICAM-1, and VCAM-1. CD7 additionally mediates the Galectin-1 induced apoptosis of T cells and facilitates the fusion of HIV-1 with target cells.
生物活性	Immobilized Recombinant Human CD7 protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.
内毒素水平	<1.0 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	1-180 aa
序列	MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPHHHHHH
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	P09564
来源	重组表达
预测分子量	16.4 kDa
SDS-PAGE	22.3-39.5 kDa, under reducing conditions; 22.8-38.0 & 21.7 kDa, under non-reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, pH 7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

ELISA: Recombinant Human CD7 Protein (rp176728)

Recombinant Human CD7 Protein (rp176728) - ELISA
Immobilized Recombinant Human CD7 Protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.

SDS-PAGE: Recombinant Human CD7 Protein (rp176728)

Recombinant Human CD7 Protein (rp176728) - SDS-PAGE
3 μg/lane of Recombinant Human CD7 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 22.3-39.5 kDa under reducing conditions and 22.8-38.0 & 21.7 kDa under non-reducing conditions.

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找到4个结果

批号(Lot Number)	证书类型	货号
ZJ24F0809488	分析证书	rp176728
ZJ24F0809489	分析证书	rp176728
ZJ24F0809490	分析证书	rp176728
ZJ24F0809491	分析证书	rp176728

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