This is a demo store. No orders will be fulfilled.

Recombinant Human Heme Oxygenase 1 Protein

  • 表达系统: E. coli
  • Accession #: P09601
  • 蛋白标签: C-His
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
rp176715-10μg
10μg 现货 Stock Image
rp176715-100μg
100μg 现货 Stock Image
rp176715-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human Heme Oxygenase 1 Protein
别名 重组人血红素加氧酶 1 蛋白
英文别名 bK286B10 | EC 1.14.99.3 | heat shock protein, 32-kD | heme oxygenase (decycling) 1 | HMOX1 | HO | HO1 | HO-1 | HO-1heme oxygenase 1 | HSP32
规格或纯度 Carrier Free, Azide Free, ≥98%(SDS-PAGE)
产品介绍


Purity:>98%, by SDS-PAGE visualized with Coomassie® Blue Staining.

Description:

Heme oxygenase (HMOX) is the rate limiting enzyme in heme catabolism. It cleaves heme to biliverdin, carbon monoxide, and iron. The biliverdin is subsequently converted to bilirubin by biliverdin reductase. The mechanism of HMOX is unique in that heme serves as the substrate of the enzyme and as the prosthetic group for the activation of iron-bound O2. HMOX activity is highest in spleen where senescent erythrocytes are sequestered and destroyed. Two isoforms, HMOX1 and HMOX2, are expressed in most tissues. HMOX1 is an inducible enzyme in response to heme, heavy metals, oxidative stress, cytokines, and many drugs. Whereas HMOX2 displays a constitutive expression. HMOX1 is expressed mainly in spleen, liver, and kidney, and HMOX2 is prominently expressed in the brain and testes. The increased expression of HMOX1 levels is related to a variety of pathological states, where it functions as a cytoprotective molecule through its by products. HMOX1 also plays important roles in the regulation of cell proliferation, differentiation, and apoptosis.

表达系统 E. coli
种属 人(Human)
氨基酸 1-261 aa
序列 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTHHHHHH
纯度 >98% (SDS-PAGE)
蛋白标签 C-His
无载体 Yes
无动物源 No
Accession # P09601
来源 重组表达
预测分子量 30.7 kDa
SDS-PAGE 28.8 kDa, reducing conditions; 28.8 kDa, non-reducing conditions

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 20mM Tris, 400mM NaCl, pH8.0
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可稳定保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human Heme Oxygenase 1 Protein (rp176715) - SDS-PAGE
Recombinant Human Heme Oxygenase 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 28.8 kDa.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到2个结果

批号(Lot Number) 证书类型 货号
ZJ23F1101872 分析证书 rp176715
ZJ23F1101871 分析证书 rp176715

溶液计算器