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Recombinant Feline CD16 Protein

  • 表达系统: HEK293
  • Accession #: Q9N2I5
  • 蛋白标签: C-His
  • 内毒素水平: <1.0 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp176261-10μg
10μg 现货 Stock Image
rp176261-50μg
50μg 现货 Stock Image
rp176261-100μg
100μg 现货 Stock Image
rp176261-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Feline CD16 Protein
别名 重组猫CD16蛋白 | 重组猫 CD16 蛋白
英文别名 D 16 | CD 16a | CD16 | CD16a | CD16a antigen | CD16B | CD16b antigen | Fc fragment of IgG | Fc fragment of IgG low affinity IIIa receptor | Fc fragment of IgG low affinity IIIa receptor (CD16) | Fc fragment of IgG receptor IIIa | Fc fragment of IgG, low a
规格或纯度 Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC). Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger (By similarity).
Mediates IgG effector functions on natural killer (NK) cells. Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation (By similarity).
Fc-binding subunit that associates with FCER1G adapter to form functional signaling complexes. Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapter with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation (By similarity).
Mediates enhanced ADCC in response to afucosylated IgGs (By similarity).

内毒素水平 <1.0 EU/μg
表达系统 HEK293
种属 猫(Feline)
氨基酸 21-207 aa
序列 ADLSKAMVVLEPEWNRVLVSDGVILKCEGAYPPGDNSAQWWHNGSVIPHRAPSYSIEAARSEDSGEYKCQTGLSEASDPVQLEVHTGWLLLQAPRWVFQEGDTIQLRCHSWKNKTVQKVQYFQDGRGKMFFHKNSDFYIPKATSKHSGSYFCRGLIGNKNESSEAVNITVQGPPVPSTSTFLPHWYQHHHHHH
纯度 >95% (SDS-PAGE)
蛋白标签 C-His
无载体 Yes
无动物源 Yes
Accession # Q9N2I5
来源 重组表达
预测分子量 21.9 kDa
SDS-PAGE 29.6-46.9 kDa, under reducing conditions; 26.8-43.1 kDa, under non-reducing conditions

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from PBS, pH 7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Feline CD16 Protein (rp176261) - SDS-PAGE
3 μg/lane of Recombinant Feline CD16 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 29.6-46.9 kDa under reducing conditions and 26.8-43.1 kDa under non-reducing conditions.

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0202909 分析证书 rp176261
ZJ24F0202910 分析证书 rp176261
ZJ24F0202911 分析证书 rp176261

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