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TL1A, 死亡受体3

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp175308-500μg
500μg 期货 Stock Image
rp175308-1mg
1mg 期货 Stock Image
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death receptor 3 (1)

基本描述

产品名称 TL1A, 死亡受体3
别名 Tumor necrosis factor ligand superfamily member 15, membrane form
英文别名 Tumor necrosis factor ligand superfamily member 15, membrane form
规格或纯度 Moligand™
作用机制 死亡受体3

关联靶点(人)

TNFRSF25 Tbio 肿瘤坏死因子受体超家族成员 25(Tumor necrosis factor receptor superfamily member 25) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

储存与运输

CAS编号和信息 rp175308

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

引用文献

1. Kakuta Y, Kinouchi Y, Negoro K, Takahashi S, Shimosegawa T.  (2006)  Association study of TNFSF15 polymorphisms in Japanese patients with inflammatory bowel disease..  Gut,  55  (10): (1527-8).  [PMID:16966713]
2. Picornell Y, Mei L, Taylor K, Yang H, Targan SR, Rotter JI.  (2007)  TNFSF15 is an ethnic-specific IBD gene..  Inflamm Bowel Dis,  13  (11): (1333-8).  [PMID:17663424]
3. Lagou S, Grapsa D, Syrigos N, Bamias G.  (2022)  The Role of Decoy Receptor DcR3 in Gastrointestinal Malignancy..  Cancer Diagn Progn,  (4): (411-421).  [PMID:35813013]
4. Danese S, Klopocka M, Scherl EJ, Romatowski J, Allegretti JR, Peeva E, Vincent MS, Schoenbeck U, Ye Z, Hassan-Zahraee M et al..  (2021)  Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study..  Clin Gastroenterol Hepatol,  19  (11): (2324-2332.e6).  [PMID:34126262]
5. Zhang T, Ning WW, Zhang J, Xu FJ, Wang XQ, Li ZB, Xie M.  (2022)  Nonylphenol regulates TL1A through the AhR/HDAC2/HNF4α pathway in endothelial cells to promote the angiogenesis of colorectal cancer..  Toxicol Appl Pharmacol,  436  (115854).  [PMID:34974051]
6. Gao Y, Wang Y, Wang X, Wang Y, Zhang X, Sun X.  (2019)  TNF-like ligand 1A is associated with progression and prognosis of human gastric cancer..  Onco Targets Ther,  12  (7715-7723).  [PMID:31571922]
7. Banfield C, Rudin D, Bhattacharya I, Goteti K, Li G, Hassan-Zahraee M, Brown LS, Hung KE, Pawlak S, Lepsy C.  (2020)  First-in-human, randomized dose-escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of PF-06480605 in healthy subjects..  Br J Clin Pharmacol,  86  (4): (812-824).  [PMID:31758576]

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