| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp174463-500μg |
500μg |
期货  |
| |
| rp174463-1mg |
1mg |
期货 |
|
| 产品名称 | linaclotide, 热稳定肠毒素受体激动剂 |
|---|---|
| 别名 | 利那洛肽 |
| 英文别名 | linaclotidum | L-Tyrosine, L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1->6), (2->10), (5->13)-tris(disulfide) | L-Tyrosine, L-cysteinyl-L-cy |
| 规格或纯度 | Moligand™ |
| 作用类型 | 激动剂 |
| 作用机制 | 热稳定肠毒素受体激动剂 |
| ALogP | -6.8 |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| CAS编号和信息 | 851199-59-2 |
|---|---|
| 分子类型 | 蛋白质 |
| 1. Shailubhai K. (2002) Therapeutic applications of guanylate cyclase-C receptor agonists.. Curr Opin Drug Discov Devel, 5 (2): (261-8). [PMID:11926132] |
| 2. Bharucha AE, Waldman SA. (2010) Taking a lesson from microbial diarrheagenesis in the management of chronic constipation.. Gastroenterology, 138 (3): (813-7). [PMID:20114092] |
| 3. Busby RW, Bryant AP, Bartolini WP, Cordero EA, Hannig G, Kessler MM, Mahajan-Miklos S, Pierce CM, Solinga RM, Sun LJ et al.. (2010) Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.. Eur J Pharmacol, 649 (1-3): (328-35). [PMID:20863829] |
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