| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp174275-500μg |
500μg |
期货  |
| |
| rp174275-1mg |
1mg |
期货 |
|
| 产品名称 | IL-10, 白细胞介素-10 受体激动剂;白细胞介素-10 受体激动剂;α 亚基 |
|---|---|
| 别名 | interleukin-10 |
| 英文别名 | interleukin-10 |
| 规格或纯度 | Moligand™ |
| 作用类型 | 激动剂 |
| 作用机制 | 白细胞介素-10 受体激动剂;白细胞介素-10 受体激动剂;α 亚基 |
| CAS编号和信息 | rp174275 |
|---|
| 1. O'Garra A, Vieira P. (2007) T(H)1 cells control themselves by producing interleukin-10.. Nat Rev Immunol, 7 (6): (425-8). [PMID:17525751] |
| 2. Schwager K, Kaspar M, Bootz F, Marcolongo R, Paresce E, Neri D, Trachsel E. (2009) Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis.. Arthritis Res Ther, 11 (5): (R142). [PMID:19781067] |
| 3. Ryan JJ, Kashyap M, Bailey D, Kennedy S, Speiran K, Brenzovich J, Barnstein B, Oskeritzian C, Gomez G. (2007) Mast cell homeostasis: a fundamental aspect of allergic disease.. Crit Rev Immunol, 27 (1): (15-32). [PMID:17430094] |
| 4. Fillatreau S, Gray D, Anderton SM. (2008) Not always the bad guys: B cells as regulators of autoimmune pathology.. Nat Rev Immunol, 8 (5): (391-7). [PMID:18437156] |
| 5. Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant S, Whiteside M, Rasco DR et al.. (2016) Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors.. J Clin Oncol, 34 (29): (3562-3569). [PMID:27528724] |
| 6. Naing A, Infante JR, Papadopoulos KP, Chan IH, Shen C, Ratti NP, Rojo B, Autio KA, Wong DJ, Patel MR et al.. (2018) PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients.. Cancer Cell, 34 (5): (775-791.e3). [PMID:30423297] |
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