| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp174173-500μg |
500μg |
期货  |
| |
| rp174173-1mg |
1mg |
期货 |
|
| 产品名称 | growth differentiation factor 15, 类似 GDNF 家族受体 alpha 的激动剂 |
|---|---|
| 别名 | 生长分化因子 15 |
| 英文别名 | GDF15 | macrophage inhibitory cytokine-1 | MIC-1 | MIC1 | PTGFB |
| 规格或纯度 | Moligand™ |
| 作用类型 | 激动剂 |
| 作用机制 | 类似 GDNF 家族受体 alpha 的激动剂 |
| CAS编号和信息 | rp174173 |
|---|
| 1. Mullican SE, Lin-Schmidt X, Chin CN, Chavez JA, Furman JL, Armstrong AA, Beck SC, South VJ, Dinh TQ, Cash-Mason TD et al.. (2017) GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.. Nat Med, 23 (10): (1150-1157). [PMID:28846097] |
| 2. Emmerson PJ, Wang F, Du Y, Liu Q, Pickard RT, Gonciarz MD, Coskun T, Hamang MJ, Sindelar DK, Ballman KK et al.. (2017) The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.. Nat Med, 23 (10): (1215-1219). [PMID:28846098] |
| 3. Yang L, Chang CC, Sun Z, Madsen D, Zhu H, Padkjær SB, Wu X, Huang T, Hultman K, Paulsen SJ et al.. (2017) GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.. Nat Med, 23 (10): (1158-1166). [PMID:28846099] |
| 4. O'Rahilly S. (2017) GDF15-From Biomarker to Allostatic Hormone.. Cell Metab, 26 (6): (807-808). [PMID:29195860] |
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