Recombinant Human CD30/TNFRSF8 Protein

COA

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: P28908
蛋白标签: C-His
生物活性: Immobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.
内毒素水平: <1.0 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp169577-10μg	10μg	现货
rp169577-50μg	50μg	现货
rp169577-100μg	100μg	现货
rp169577-1mg	1mg	现货

查看相关系列

点击查看蛋白信息: TNFRSF8

Accession#:P28908 (7) CD30 (9) Gene ID:943 (7) TNFRSF8 (7)

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基本描述

产品名称	Recombinant Human CD30/TNFRSF8 Protein
别名	重组人CD30/TNFRSF8蛋白 \| 重组人 CD30/TNFRSF8 蛋白
英文别名	CD30 \| CD30KI-1 \| CD30L receptor \| cytokine receptor CD30 \| D1S166EKi-1 \| Ki-1 antigen \| Lymphocyte activation antigen CD30 \| TNFRSF8 \| tumor necrosis factor receptor superfamily member 8 \| tumor necrosis factor receptor superfamily, member 8 \| CD30 antig
规格或纯度	Animal Free, Carrier Free, Bioactive, ActiBioPure™, ≥95%(SDS-PAGE)
产品介绍	Protein Function:： CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
生物活性	Immobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.
内毒素水平	<1.0 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	1-379 aa
序列	MRVLLAALGLLFLGALRAFPQDRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRDDLVEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSRDDLVEKTPCAWNSSRTCECRPGMICATSATNSCARCVPYPICAAETVTKPQDMAEKDTTFEAPPLGTQPDCNPTPENGEAPASTSPTQSLLVDSQASKTLPIPTSAPVALSSTGKHHHHHH
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	P28908
来源	重组表达
预测分子量	39.2 kDa
SDS-PAGE	55.0-99.0 kDa, under reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, pH7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

ELISA: Recombinant Human CD30/TNFRSF8 Protein (rp169577)

Recombinant Human CD30/TNFRSF8 Protein (rp169577) - ELISA
Immobilized Recombinant Human CD30/TNFRSF8 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC₅₀ of 119.9 ng/mL.

SDS-PAGE: Recombinant Human CD30/TNFRSF8 Protein (rp169577)

Recombinant Human CD30/TNFRSF8 Protein (rp169577) - SDS-PAGE
3 μg/lane of Recombinant Human CD30/TNFRSF8 Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 55.0-99.0 kDa under reducing conditions.

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找到4个结果

批号(Lot Number)	证书类型	货号
ZJ24F0708053	分析证书	rp169577
ZJ24F0708050	分析证书	rp169577
ZJ24F0708051	分析证书	rp169577
ZJ24F0708052	分析证书	rp169577

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