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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp154139-10μg |
10μg |
现货 ![]() |
| |
| rp154139-20μg |
20μg |
现货 ![]() |
| |
| rp154139-100μg |
100μg |
现货 ![]() |
| |
| rp154139-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | Recombinant Mouse IL-13 Protein |
|---|---|
| 别名 | 重组小鼠 IL-13 蛋白 |
| 英文别名 | Allergic rhinitis | ALRH | BHR 1 | BHR1 | Bronchial hyperresponsiveness 1 (bronchial asthma) | IL 13 | IL-13 | Il13 | IL13_HUMAN | Interleukin 13 | Interleukin-13 | interleukin13 | MGC116786 | MGC116788 | MGC116789 | NC 30 | NC30 | P 600 | P60 |
| 规格或纯度 | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE&HPLC) |
| 产品介绍 |
Murine Interleukin-13 (IL-13) is expressed by the IL13 gene located on the chromosome 11 and secreted by many cell types, especially T helper type 2 (Th2) cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human, mouse and rat IL-13 share low homology, but have cross species activity. Recombinant Murine IL-13 is a 12.3kDa protein consisting of 111 amino acid residues Purity >98%(SDS-PAGE,HPLC) Function Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses . Positively regulates IL31RA expression in macrophages. |
| 生物活性 | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically <4ng/mL. |
| 内毒素水平 | <0.01 EU/μg |
| 表达系统 | E. coli |
| 种属 | 小鼠(Mouse) |
| 氨基酸 | 22-131 aa |
| 序列 | MPVPRSVSLPLTLKELIEELSNITQDQTPLCNGSMVWSVDLAAGGF CVALDSLTNISNCNAIYRTQRILHGLCNRKAPTTVSSLPDTKIEVAHF ITKLLSYTKQLFRHGPF |
| 纯度 | >98%(SDS-PAGE,HPLC) |
| 蛋白标签 | No tag |
| 蛋白长度 | Full length protein |
| 无载体 | Yes |
| 无动物源 | Yes |
| Accession # | P20109 |
| 来源 | 重组表达 |
| 预测分子量 | 12.3 kDa |
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4 |
| 复溶 | 1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. 2、 Reconstitute in a sterile aqueous buffer to an appropriate concentration. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 长期储存时,产品应≤ -20℃。避免冷冻/解冻循环。 |
| 分子类型 | 蛋白质 |
Recombinant Mouse IL-13 Protein (rp154139)-Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically <4ng/mL.
Recombinant Mouse IL-13 Protein (rp154139)-SDS-PAGE
3μg/lane of Recombinant Mouse IL-13 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 11.2 kDa.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 |
¥599.90