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Recombinant Human TARC/CCL17 Protein

COA COA
  • 表达系统: E. coli
  • Accession #: Q92583
  • 蛋白标签: No tag
  • 生物活性: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.
  • 内毒素水平: <0.01 EU/μg
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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp152075-10μg
 10μg 现货 Stock Image
rp152075-50μg
 50μg 现货 Stock Image
rp152075-100μg
 100μg 现货 Stock Image
rp152075-1mg
 1mg 期货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
查看相关系列
点击查看蛋白信息: CCL17
Accession#:Q92583 (2) CCL17 (2) Gene ID:6361 (2) TARC (1)
main product photo

基本描述

产品名称 Recombinant Human TARC/CCL17 Protein
别名 重组人TARC/CCL17蛋白
英文别名 CC chemokine TARC | Small-inducible cytokine A17 | Thymus and activation-regulated chemokine
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE&HPLC)
产品介绍


Purity
> 97% by SDS-PAGE and HPLC analyses.

Function
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
生物活性 Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.
内毒素水平 <0.01 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 24-94 aa
序列 ARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS
纯度 ＞97% (SDS-PAGE and HPLC)
蛋白标签 No tag
蛋白长度 Full length protein
无载体 Yes
无动物源 Yes
Accession # Q92583
来源 重组表达
预测分子量 8.1kDa
SDS-PAGE 8.1kDa

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from a 0.2 mm filtered concentrated solution in 20mM PBS, pH 7.4, 150mM NaCl.
复溶 Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL.
储存温度 -20°C储存
运输条件 超低温冰袋运输
稳定性与储存 使用手动除霜冰柜，避免反复冻融循环。自收到之日起 12 个月，-20 至 -70 °C。复溶后 1 个月，无菌条件下 2 至 8 °C。3 个月，复溶后在无菌条件下 -20 至 -70 °C。
分子类型 蛋白质

图片

Recombinant Human TARC/CCL17(rp152075)-Protein Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/mL.

Recombinant Human TARC/CCL17 Protein (rp152075)-SDS-PAGE
Recombinant Human TARC/CCL17 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 8.1 kDa under reducing conditionsand and 8.0-13.0kDa under non-reducing conditions.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number) 证书类型 货号
ZJ23F0600429 分析证书 rp152075
ZJ23F0600428 分析证书 rp152075
ZJ23F0600430 分析证书 rp152075

可替换产品

  1. Recombinant Human CCL17/TARC Protein
    Recombinant Human CCL17/TARC Protein

    ¥599.90

引用文献

1. Bernardini G, Hedrick J, Sozzani S, Luini W, Spinetti G, Weiss M, Menon S, Zlotnik A, Mantovani A, Santoni A et al..  (1998)  Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor..  Eur J Immunol,  28  (2): (582-8).  [PMID:9521068]
2. Regenass P, Abboud D, Daubeuf F, Lehalle C, Gizzi P, Riché S, Hachet-Haas M, Rohmer F, Gasparik V, Boeglin D et al..  (2018)  Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia..  J Med Chem,  61  (17): (7671-7686).  [PMID:30106292]
3. Imai, T T and 5 more authors..  (1996)  Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector..  The Journal of biological chemistry,  (30): [PMID:8702936]
4. Imai, T T and 5 more authors..  (1997)  The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4..  The Journal of biological chemistry,  (6): [PMID:9169480]
5. Loftus, B J BJ and 18 more authors..  (1999)  Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q..  Genomics,  (15): [PMID:10493829]
6. Garlisi, C G CG and 6 more authors..  (1999)  The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8..  European journal of immunology,  [PMID:10540332]
7. Asojo, Oluwatoyin A OA, Boulègue, Cyril C, Hoover, David M DM, Lu, Wuyuan W and Lubkowski, Jacek J..  (2003)  Structures of thymus and activation-regulated chemokine (TARC)..  Acta crystallographica. Section D, Biological crystallography,  [PMID:12832759]
8. Achuthan, Adrian A and 19 more authors..  (2016)  Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation..  The Journal of clinical investigation,  (1): [PMID:27525438]
9. Hsu, Amy T AT and 6 more authors..  (2018)  Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages..  The Journal of biological chemistry,  (20): [PMID:29871928]

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