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受体和细胞表面标记物
Recombinant Human Poliovirus Receptor/PVR Protein

Recombinant Human Poliovirus Receptor/PVR Protein

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: P15151-1
蛋白标签: C-hFc & His
生物活性: Immobilized Human TIGIT (rp152378) at 1.5 μg/mL can bind Recombinant Human Poliovirus Receptor/PVR Protein (rp150374) with a linear range of 0.15 - 1.2 μg/mL.
内毒素水平: <0.1 EU/μg

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货号 (SKU)	包装规格	是否现货
rp150374-10μg	10μg	现货
rp150374-50μg	50μg	现货
rp150374-100μg	100μg	现货
rp150374-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: PVR 点击查看蛋白信息: ARRDC2

Accession#:P15151 (4) Gene ID:5817 (4) Poliovirus Receptor (3) PVR (5)

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基本描述

产品名称	Recombinant Human Poliovirus Receptor/PVR Protein
别名	重组人PVR蛋白 \| 重组人Poliovirus Receptor蛋白 \| 重组人脊髓灰质炎病毒受体蛋白 \| 重组人类脊髓灰质炎病毒受体/PVR 蛋白
英文别名	CD155 \| CD155 antigen \| FLJ25946 \| HVED \| mE4 \| NECL 5 \| Necl-5 \| Necl5 \| Nectin like 5 \| Nectin like protein 5 \| Nectin-like protein 5 \| Ortholog of mouse Tage4 \| Poliovirus receptor \| PVR \| PVR_HUMAN \| PVS \| Taa1 \| Tage 4 \| TAGE4 \| nectin-like 5 \| PVSFL
规格或纯度	ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍	Purity ≥95% SDS-PAGE. Endotoxin level <0.1 EU/µg Function Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.
生物活性	Immobilized Human TIGIT (rp152378) at 1.5 μg/mL can bind Recombinant Human Poliovirus Receptor/PVR Protein (rp150374) with a linear range of 0.15 - 1.2 μg/mL.
内毒素水平	<0.1 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	28-343 aa
序列	DVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
纯度	≥95% (SDS-PAGE)
蛋白标签	C-hFc & His
无载体	Yes
无动物源	Yes
Accession #	P15151-1
来源	重组表达
预测分子量	62.5 kDa
SDS-PAGE	96.1 kDa, under reducing conditions ; 204.4 kDa, under non-reducing conditions.

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶	Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型	蛋白质

图片

Protein Bioactivity: Recombinant Human Poliovirus Receptor/PVR Protein (rp150374)

Recombinant Human Poliovirus Receptor/PVR Protein (rp150374) - Protein Bioactivity
Immobilized Human TIGIT (rp152378) at 1.5 μg/mL can bind Recombinant Human Poliovirus Receptor/PVR Protein (rp150374) with a linear range of 0.15 - 1.2 μg/mL.

SDS-PAGE: Recombinant Human Poliovirus Receptor/PVR Protein (rp150374)

Recombinant Human Poliovirus Receptor/PVR Protein (rp150374) - SDS-PAGE
3 μg/lane of Recombinant Human Poliovirus Receptor/PVR was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 96.1 kDa under reducing conditions and 204.4 kDa under non-reducing conditions.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0404847	分析证书	rp150374
ZJ24F0404848	分析证书	rp150374
ZJ24F0404849	分析证书	rp150374

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