Recombinant Human MUC-1 Protein

COA

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: P15941-11
蛋白标签: C-hFc & His
生物活性: Measured by its ability to increase beta-catenin levels in the cytoplasm and nucleus of HCT116 human colon adenocarcinoma cells. 0.01-1 ng/mL of Recombinant Human MUC-1 can effectively increase beta-catenin levels.
内毒素水平: <0.1 EU/μg

有货

库存信息

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
rp148996-10μg	10μg	现货
rp148996-50μg	50μg	现货
rp148996-100μg	100μg	现货
rp148996-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: MUC1

Accession#:P15941 (22) CA153 (4) Gene ID:4582 (22) MUC1 (22)

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基本描述

产品名称	Recombinant Human MUC-1 Protein
别名	粘蛋白1(MUC1)重组蛋白 \| 重组人类 MUC-1 蛋白
英文别名	ADMCKD \| ADMCKD1 \| Breast carcinoma associated antigen DF3 \| Breast carcinoma-associated antigen DF3 \| CA 15-3 \| CA15 3 \| CA15 3 antigen \| CA15-3 \| CA15.3 \| Cancer antigen 15-3 \| Carcinoma associated mucin \| Carcinoma-associated mucin \| CD 227 \| CD227 \| D
规格或纯度	ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍	Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
生物活性	Measured by its ability to increase beta-catenin levels in the cytoplasm and nucleus of HCT116 human colon adenocarcinoma cells. 0.01-1 ng/mL of Recombinant Human MUC-1 can effectively increase beta-catenin levels.
内毒素水平	<0.1 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	1-167 aa
序列	MTPGTQSPFFLLLLLTVLTATTAPKPATVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAFNSSLEDPSTDYYQELQRDISEMFLQIYKQGGFLGLSNIKFRPGSVVVQLTLAFREGTINVHDVETQFNQYKTEAASRYNLTISDVSVSDVPFPFSAQSGAGVPGENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
纯度	≥95% (SDS-PAGE)
蛋白标签	C-hFc & His
无载体	Yes
无动物源	Yes
Accession #	P15941-11
来源	重组表达
预测分子量	45 kDa
SDS-PAGE	60-75 kDa, under reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶	Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型	蛋白质

图片

Protein Bioactivity: Recombinant Human MUC-1 Protein (rp148996)

Recombinant Human MUC-1 Protein (rp148996) - Protein Bioactivity
Measured by its ability to increase beta-catenin levels in the HCT116 human colon adenocarcinoma cells. 0.01 -1.0 ng/mL of Recombinant Human MUC-1 Protein (rp148996) can effectively increase beta-catenin levels.

SDS-PAGE: Recombinant Human MUC-1 Protein (rp148996)

Recombinant Human MUC-1 Protein (rp148996) - SDS-PAGE
3 μg/lane of Recombinant Human MUC-1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 55 - 65 kDa.

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找到6个结果

批号(Lot Number)	证书类型	货号
ZJ24F1214954	分析证书	rp148996
ZJ24F1214952	分析证书	rp148996
ZJ24F1214953	分析证书	rp148996
ZJ24F0708027	分析证书	rp148996
ZJ24F0708025	分析证书	rp148996
ZJ24F0708026	分析证书	rp148996

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