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Recombinant Human LTBR Protein

  • 表达系统: HEK293
  • Accession #: P36941
  • 蛋白标签: C-hFc & His
  • 生物活性: Immobilized Recombinant Human LIGHT at 1 μg/mL (100 μL/well) can bind Recombinant Human LTBR with a linear range of 15-55 ng/mL.
  • 内毒素水平: <0.1 EU/μg
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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp148424-10μg
10μg 现货 Stock Image
rp148424-50μg
50μg 现货 Stock Image
rp148424-100μg
100μg 现货 Stock Image
rp148424-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human LTBR Protein
别名 重组人 LTBR 蛋白
英文别名 Lymphotoxin-beta receptor | TNFR-III | TNF-RIII | Tumor necrosis factor C receptor | Tumor necrosis factor receptor 2-related protein | Tumor necrosis factor receptor type III
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity
>95% SDS-PAGE.
Additional sequence information
Extracellular domain fused with Fc tag at the C-terminus.

Function
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

生物活性 Immobilized Recombinant Human LIGHT at 1 μg/mL (100 μL/well) can bind Recombinant Human LTBR with a linear range of 15-55 ng/mL.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 人(Human)
氨基酸 31-227aa
序列 QAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
纯度 >95% (SDS-PAGE)
蛋白标签 C-hFc & His
无载体 Yes
无动物源 Yes
Accession # P36941
来源 重组表达
预测分子量 49kDa
SDS-PAGE 61.5 kDa, under reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Liquid PBS, pH 7.4, containing 5% trehalose, 5% mannitol
复溶 Reconstitute in water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。
分子类型 蛋白质

图片

Recombinant Human LTBR Protein (rp148424) - Protein Bioactivity
Immobilized Recombinant Human LIGHT at 1.0 μg/mL can bind Recombinant Human LTBR Protein (rp148424) with a linear range of 15.0 - 55.0 ng/mL.

Recombinant Human LTBR Protein (rp148424) - SDS-PAGE
3 μg/lane of Recombinant Human LTBR Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing a band at 61.5 kDa under reducing condition.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0102339 分析证书 rp148424
ZJ24F0102340 分析证书 rp148424
ZJ24F0102341 分析证书 rp148424

引用文献

1. Crowe, P D PD and 9 more authors..  (1994)  A lymphotoxin-beta-specific receptor..  Science (New York, N.Y.),  (29): [PMID:8171323]
2. Baens, M M, Chaffanet, M M, Cassiman, J J JJ, van den Berghe, H H and Marynen, P P..  (1993)  Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid..  Genomics,  [PMID:8486360]
3. Nakano, H H and 6 more authors..  (1996)  TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor..  The Journal of biological chemistry,  (21): [PMID:8663299]
4. Matsumoto, M M and 10 more authors..  (1997)  Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor..  Journal of virology,  [PMID:8995654]
5. Mizushima, S S and 8 more authors..  (1998)  Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5)..  Gene,  (30): [PMID:9511754]
6. Krajewska, M M and 11 more authors..  (1998)  TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues..  The American journal of pathology,  [PMID:9626059]
7. Wu, M Y MY, Wang, P Y PY, Han, S H SH and Hsieh, S L SL..  (1999)  The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells..  The Journal of biological chemistry,  (23): [PMID:10207006]
8. Rooney, I A IA and 8 more authors..  (2000)  The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells..  The Journal of biological chemistry,  (12): [PMID:10799510]
9. Scherer, Steven E SE and 216 more authors..  (2006)  The finished DNA sequence of human chromosome 12..  Nature,  (16): [PMID:16541075]

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