This is a demo store. No orders will be fulfilled.

Recombinant Human IL-12 p40 Protein

  • 表达系统: HEK293
  • Accession #: P29460
  • 蛋白标签: C-His
  • 生物活性: Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is 2.00-20.0 ng/mL.
  • 内毒素水平: <0.1 EU/μg
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
rp147380-10μg
10μg 现货 Stock Image
rp147380-50μg
50μg 现货 Stock Image
rp147380-100μg
100μg 现货 Stock Image
rp147380-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-12 p40 Protein
别名 重组人 IL-12 p40 蛋白 | 重组人白介素12B蛋白
英文别名 CLMF p40 | CLMF | CLMF2 | Cytotoxic lymphocyte maturation factor 40 kDa subunit | IL12 p40 | IL-12 p40 | IL-12 subunit p40 | IL12B | IL-12B | IL-12BNK cell stimulatory factor chain 2 | interleukin 12, p40 | interleukin 12B (natural killer cell stimulatory
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Purity
≥95% SDS-PAGE.
Endotoxin level
<0.1 EU/µg
Function
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

生物活性 Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is 2.00-20.0 ng/mL.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 人(Human)
氨基酸 23-328 aa
序列 IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCSHHHHHH
纯度 ≥95% (SDS-PAGE)
蛋白标签 C-His
无动物源 Yes
Accession # P29460
来源 重组表达
预测分子量 35.5 kDa
SDS-PAGE 50 kDa under reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human IL-12 p40 Protein (rp147380) - SDS-PAGE
2 μg/lane of Recombinant Human IL-12 p40 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 35 - 48 kDa.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到3个结果

批号(Lot Number) 证书类型 货号
ZJ25F0825391 分析证书 rp147380
ZJ25F0825390 分析证书 rp147380
ZJ25F0825389 分析证书 rp147380

溶液计算器