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Recombinant Human Activin RIIA Protein

  • 表达系统: HEK293
  • Accession #: P27037-1
  • 蛋白标签: C-His
  • 生物活性: Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.
  • 内毒素水平: <0.1 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp142510-10μg
10μg 现货 Stock Image
rp142510-50μg
50μg 现货 Stock Image
rp142510-100μg
100μg 现货 Stock Image
rp142510-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human Activin RIIA Protein
别名 激活素A受体ⅡA(ACVR2A)重组蛋白 | 重组人类激活素 RIIA 蛋白
英文别名 Activin receptor type IIA | ACTRIIA | ACTR-IIA | EC 2.7.11.30 | Activin A receptor type IIA | Activin receptor type 2A | Activin receptor type IIA | Activin receptor type-2A | ACTR 2 | ACTR IIA | ACTR-IIA | ACTR2 | ACTRII | ACTRIIA | Acvr 2A | Acvr 2 | Ac
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

生物活性 Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 人(Human)
氨基酸 20-134 aa
序列 AILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPHHHHHH
纯度 ≥95% (SDS-PAGE)
蛋白标签 C-His
无载体 Yes
无动物源 Yes
Accession # P27037-1
来源 重组表达
预测分子量 13 kDa
SDS-PAGE 30.0 - 35.0 kDa, under reducing conditions; 30.0 - 35.0 kDa, under non-reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human Activin RIIA Protein (rp142510) - SDS-PAGE
3 μg/lane of Recombinant Human Activin RIIA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 30.0 - 35.0 kDa.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0606777 分析证书 rp142510
ZJ24F0606775 分析证书 rp142510
ZJ24F0606776 分析证书 rp142510

引用文献

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