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(R)-(+)-α-甲基苄胺
有货
库存信息
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| R432669-500g |
500g |
现货  |
|
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基本描述
| 别名 | (R)-(+)-1-苯乙胺 |
|---|---|
| 英文别名 | (r)-(+)-1-phenethylamine | A6546 | (R)-(-)-1-phenylethylamine | (R)-(+)-alpha-Methylbenzylamine, for chiral derivatization, >=99.0% | (R)-(1-phenylethyl)amine | (R)-alpha-methylbenzylarnine | QSC | UNII-V022ZK8GZ5 | (R)-(-)-alpha-methylbenzylamine | (R)-1 |
| 规格或纯度 | ≥99.0% |
| 英文名称 | (R)-(+)-α-Methylbenzylamine |
| 产品介绍 |
General Description ( R )-(+)-α-Methylbenzylamine is a chiral amine. Application ( R )-(+)-α-Methylbenzylamine may be used as a substrate to synthesize: ( S )-α-amino phosphonates N -{( S )-[cyclohexan-( S )-2-ol]}-( R )-α-methylbenzyl amine and N -{( R )-[cyclohexan-( R )-2-ol]}-( R )-α-methylbenzyl amine R -α-aminonitriles |
| 纯度 | ≥99.0% |
关联靶点（人）
MAOB
Tclin
Monoamine oxidase B
(8835 活性数据)
PNMT
Tchem
Phenylethanolamine N-methyltransferase
(540 活性数据)
关联靶点（其它种属）
Grin1
Glutamate NMDA receptor (6467 活性数据)
Adra2c
Adrenergic receptor alpha-2 (3313 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| EC号 | 223-423-4 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (1R)-1-phenylethanamine |
| INCHI | 1S/C8H11N/c1-7(9)8-5-3-2-4-6-8/h2-7H,9H2,1H3/t7-/m1/s1 |
| InChi Key | RQEUFEKYXDPUSK-SSDOTTSWSA-N |
| Smiles | C[C@@H](N)c1ccccc1 |
| Isomeric SMILES | C[C@H](C1=CC=CC=C1)N |
| PubChem CID | 643189 |
| 分子量 | 121.18 |
| Beilstein号 | 2410916 |
化学和物理性质
| 密度 | 0.952g/mLat 20°C (lit.) |
|---|---|
| 折光率 | 1.53 |
| 比旋光度 | 39° (neat) |
| 闪点(℃) | 70°C |
| 沸点 | 187-189 °C |
| 熔点 | -10 °C |
| 分子量 | 121.180 g/mol |
| XLogP3 | 1.200 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 1 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 121.089 Da |
| 单同位素质量Monoisotopic Mass | 121.089 Da |
| 拓扑极表面积Topological Polar Surface Area | 26.000 Ų |
| 重原子数Heavy Atom Count | 9 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 74.600 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 1 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
安全和危险性（GHS）
| 象形图 | GHS05, GHS07 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H302: 吞食有害 H312: 皮肤接触有害 H314: 造成严重的皮肤灼伤和眼睛损伤 H318: 造成严重的眼睛损伤 |
| 预防措施声明 |
P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P363: 再次使用之前，请清洗受污染的衣物。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P302+P361+P354: 如果接触皮肤：立即脱掉所有被污染的衣服。立即用水冲洗几分钟。 P316: 立即寻求紧急医疗救助。 |
| WGK Germany | 3 |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
可替换产品
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R(+)-α-甲基苄胺¥30.90
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(S)-(-)- α-甲基苄胺¥29.90
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(S)-(-)- α-甲基苄胺¥29.90
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R-(+)-α-甲基苄胺¥39.90
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(S)-(-)- α-甲基苄胺¥205.90
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(R)-(+)-N-烯丙基-α-甲基苄胺¥1,367.90
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4-氟-α-甲基苄胺¥105.90
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(R)-4-氟-α-甲基苄胺¥1,184.90
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(R)-(+)-α-甲基苄胺¥39.90
此产品的引用文献
引用文献
| 1. R Moaddel,S Patel,K Jozwiak,R Yamaguchi,P C Ho,I W Wainer. (2005-08-23) Enantioselective binding to the human organic cation transporter-1 (hOCT1) determined using an immobilized hOCT1 liquid chromatographic stationary phase.. Chirality, 17 ((8)): (501-506). [PMID:16113995] |
| 2. Tran Quoc Trung,Jong Moon Kim,Kyeong Ho Kim. (2006-02-24) Preparative method of R-(-)-lbuprofen by diastereomer crystallization.. Archives of pharmacal research, 29 ((1)): (108-111). [PMID:16491852] |
| 3. Maria Cammenberg,Karl Hult,Seongsoon Park. (2006-09-23) Molecular basis for the enhanced lipase-catalyzed N-acylation of 1-phenylethanamine with methoxyacetate.. Chembiochem : a European journal of chemical biology, 7 ((11)): (1745-1749). [PMID:16991170] |
| 4. Antoine Fadel,Nabil Lahrache. (2007-01-30) An efficient synthesis of enantiomerically pure (R)-pipecolic acid, (S)-proline, and their N-alkylated derivatives.. The Journal of organic chemistry, 72 ((5)): (1780-1784). [PMID:17256910] |
| 5. Abraham R Martin,David Shonnard,Sachin Pannuri,Sanjay Kamat. (2007-06-22) Characterization of free and immobilized (S)-aminotransferase for acetophenone production.. Applied microbiology and biotechnology, 76 ((4)): (843-851). [PMID:17581749] |
| 6. Andrew T Fischer,Richard M Pagni,Robert N Compton. (2007-06-23) A study of the liquid and solvent properties of optically active and racemic alpha-methylbenzylamine.. The journal of physical chemistry. B, 111 ((28)): (8187-8196). [PMID:17583940] |
| 7. G Palaprat,J-D Marty,D Langevin,H Finkelmann,M Mauzac. (2007-07-20) Enantioselective absorption of chirally doped liquid crystalline networks studied by the use of an electronic microbalance.. The journal of physical chemistry. B, 111 ((31)): (9239-9243). [PMID:17636978] |
| 8. Ramón Guzmán-Mejía,Gloria Reyes-Rangel,Eusebio Juaristi. (2007-11-17) Preparation of chiral derivatives of beta-Ala containing the alpha-phenylethyl group: useful starting materials for the asymmetric synthesis of beta-amino acids.. Nature protocols, 2 ((11)): (2759-2766). [PMID:18007611] |
| 9. Yan-Song Zheng,Ao Ji,Xian-Jie Chen,Jin-Lan Zhou. (2007-11-21) Enantioselective nanofiber-spinning of chiral calixarene receptor with guest.. Chemical communications (Cambridge, England), ((32)(32)): (3398-3400). [PMID:18019510] |
| 10. Paul E Harrington,Christopher Fotsch. (2008-01-29) Calcium sensing receptor activators: calcimimetics.. Current medicinal chemistry, 14 ((28)): (3027-3034). [PMID:18220738] |
| 11. Andrew M Kelly,Yolanda Pérez-Fuertes,John S Fossey,Sonia Lozano Yeste,Steven D Bull,Tony D James. (2008-02-16) Simple protocols for NMR analysis of the enantiomeric purity of chiral diols.. Nature protocols, 3 ((2)): (215-219). [PMID:18274523] |
| 12. Hyungdon Yun,Byung-Gee Kim. (2008-11-11) Asymmetric synthesis of (S)-alpha-methylbenzylamine by recombinant Escherichia coli co-expressing omega-transaminase and acetolactate synthase.. Bioscience, biotechnology, and biochemistry, 72 ((11)): (3030-3033). [PMID:18997410] |
| 13. Bartosz Lewandowski,Slawomir Jarosz. (2008-12-03) Chiral recognition of alpha-phenylethylamine by sucrose-based macrocyclic receptors.. Chemical communications (Cambridge, England), ((47)(47)): (6399-6401). [PMID:19048168] |
| 14. Shao-Hua Huang,Zheng-Wu Bai,Ji-Wen Feng. (2009-02-19) Chiral self-discrimination of the enantiomers of alpha-phenylethylamine derivatives in proton NMR.. Magnetic resonance in chemistry : MRC, 47 ((5)): (423-427). [PMID:19224544] |
| 15. Jinzhao Wang,Su Zeng,Danhua Wang,Gongyun Hu. (2009-10-07) [Determination of optical purity of alpha-phenylethylamine by high performance liquid chromatography with pre-column derivatization].. Se pu = Chinese journal of chromatography, 27 ((3)): (376-378). [PMID:19803150] |
| 16. Manuel Algarra,José E Rodríguez-Borges,Joaquim C G Esteves da Silva. (2009-12-31) LC-MS identification of derivatized free fatty acids from adipocere in soil samples.. Journal of separation science, 33 ((2)): (143-154). [PMID:20041447] |
| 17. Christian Merten,Marc Amkreutz,Andreas Hartwig. (2010-02-27) VCD study of alpha-methylbenzyl amine derivatives: detection of the unchanged chiral motif.. Chirality, 22 ((8)): (754-761). [PMID:20186757] |
| 18. Ignacio Caretti,Emma Carter,Ian A Fallis,Damien M Murphy,Sabine Van Doorslaer. (2011-10-14) Interactions of an asymmetric amine with a non-C2 symmetric Cu-salen complex: an EPR/ENDOR and HYSCORE investigation.. Physical chemistry chemical physics : PCCP, 13 ((45)): (20427-20434). [PMID:21993696] |
| 19. Barry Lygo,Umar Butt,Maria Cormack. (2012-05-23) Synthesis and evaluation of atropos dihydro-5H-dibenzazepinium halide PTCs derived from α-methylbenzylamine.. Organic & biomolecular chemistry, 10 ((25)): (4968-4976). [PMID:22614161] |
| 20. Sachin R Chaudhari,N Suryaprakash. (2012-06-28) Simple and efficient methods for discrimination of chiral diacids and chiral alpha-methyl amines.. Organic & biomolecular chemistry, 10 ((31)): (6410-6419). [PMID:22735343] |
| 21. Stuart J Khan,Lili Wang,Nor H Hashim,James A McDonald. (2014-12-17) Distinct enantiomeric signals of ibuprofen and naproxen in treated wastewater and sewer overflow.. Chirality, 26 ((11)): (739-746). [PMID:25513681] |
| 22. Zhixu Zhou,Linwei Li,Ning Yan,Lei Du,Changshan Sun,Tiemin Sun. (2015-11-28) Synthesis, Crystal Structure, Absolute Configuration and Antitumor Activity of the Enantiomers of 5-Bromo-2-chloro-N-(1-phenylethyl)pyridine-3-sulfonamide.. Molecules (Basel, Switzerland), 20 ((11)): (20926-20938). [PMID:26610458] |
| 23. Qian Wang, Limei Sheng, Xuan Guo, Rong Chen, Chengjie Zhou, Fu Yang. (2023) Functionalized poly(ionic liquid)s bridging Pd NPs and lipase for highly efficient dynamic kinetic resolution of chiral amine. APPLIED CATALYSIS A-GENERAL, 666 (119426). [10.1016/j.apcata.2023.119426] |
| 24. Yuanyuan Li, Jinming Liu, Wei Li, Yingru Li, Wei Zhao, Haiquan Zhang. (2023) Enhancing the photothermal performance of graphene oxide by embedding perylene diimide radical anions/α-phenylethylamine hydrogen bonded complexes in graphene oxide films for solar water evaporation. NEW JOURNAL OF CHEMISTRY, 47 (21): (10372-10380). [10.1039/D3NJ01145C] |
| 25. Shuang Jiang, Yuxin Song, Huimin Kang, Bin Li, Kunlong Yang, Guoxiang Xing, Ying Yu, Siyi Li, Peisheng Zhao, Tianyong Zhang. (2022) Ligand Exchange Strategy to Achieve Chiral Perovskite Nanocrystals with a High Photoluminescence Quantum Yield and Regulation of the Chiroptical Property. ACS Applied Materials & Interfaces, 14 (2): (3385–3394). [PMID:34932328] [10.1021/acsami.1c18978] |
| 26. Ruiheng Pan, Kai Wang, Zhi-Gang Yu. (2022) Magnetic-field manipulation of circularly polarized photoluminescence in chiral perovskites. Materials Horizons, 9 (2): (740-747). [PMID:34878471] [10.1039/D1MH01154E] |
| 27. Xuejiao Yang, Yuhe Shen, Jiayu Liu, Yuefei Wang, Wei Qi, Rongxin Su, Zhimin He. (2021) Rational Design of Chiral Nanohelices from Self-Assembly of Meso-tetrakis (4-Carboxyphenyl) Porphyrin-Amino Acid Conjugates. LANGMUIR, 37 (44): (13067–13074). [PMID:34711055] [10.1021/acs.langmuir.1c02213] |
| 28. Youming Huang, Hongyi Chen, Wenting Zheng, Qingle Zeng. (2020) Cu2O-catalyzed C–S coupling of quaternary ammonium salts and sodium alkane-/arene-sulfinates. TETRAHEDRON LETTERS, 61 (152320). [10.1016/j.tetlet.2020.152320] |
| 29. Li-Xiao He, Chun-Rong Tian, Jun-Hui Zhang, Wen Xu, Bo Peng, Sheng-Ming Xie, Min Zi, Li-Ming Yuan. (2019) Chiral metal-organic cages used as stationary phase for enantioseparations in capillary electrochromatography. ELECTROPHORESIS, 41 (1-2): (104-111). [PMID:31709552] [10.1002/elps.201900294] |
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| 31. Lei Shi,Yizhan Wang,Bao Li,Lixin Wu. (2014-05-09) Polyoxometalate complexes for oxidative kinetic resolution of secondary alcohols: unique effects of chiral environment, immobilization and aggregation.. Dalton transactions (Cambridge, England : 2003), 43 ((24)): (9177-9188). [PMID:24810246] |
| 32. Haotian Gao, Yu Chen, Ruxi Zhang, Rui Cao, Yong Wang, Yunfei Tian, Yin Xiao. (2024) Dual-ligand quasi-2D perovskites with chiral-induced spin selectivity for room temperature spin-LEDs. Materials Horizons, 11 (12): (2906-2913). [PMID:38567407] [10.1039/D3MH02029K] |
| 33. Yizhen Zhang, Yu-Cai He, Cuiluan Ma. (2024) Efficient synthesis of vanillylamine through bioamination of lignin-derived vanillin by recombinant E. coli containing ω-transaminase from Caulobacter sp. D5 in dimethyl sulfoxide-water. BIORESOURCE TECHNOLOGY, 413 (131526). [PMID:39321936] [10.1016/j.biortech.2024.131526] |