| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| R283957-1mg |
1mg |
现货  |
| |
| R283957-10mg |
10mg |
期货 |
|
| 规格或纯度 | ≥90%(SDS-PAGE) |
|---|---|
| 英文名称 | Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
胰岛素样生长因子-1（IGF-1）是一种分子量为7.6kD的激素，其分子结构与胰岛素类似。IGF-1的主要作用机理是通过与其特异性受体（IGF1R）结合来诱导细胞内的信号传导。IGF-1是AKT信号通路的最有效的激活因子之一，激活AKT信号通路后，刺激细胞生长及增殖，并抑制细胞凋亡。IGF-1 LR3在完整的IGF-1分子的N端添加了13个氨基酸形成83个氨基酸的长链IGF-1，并将IGF-1分子的第3个氨基酸谷氨酸（E）用精氨酸（R）取代，所以称为R3。IGF-1 LR3与未作修饰的IGF-1相比，具有更高的稳定性和生物活性。 规格参数 来源 大肠杆菌 外观 白色冻干粉 活性 ≥1.0×106IU/mg pH值 6.5-7.5 分子量 7.6kD 内毒素 <5EU/mg CAS No 946870-92-4 注意事项 复溶：建议用无菌水重溶rIGF-1 LR3冻干粉至100-200 ug/ml，可用其他溶剂进行进一步稀释。溶解后的rIGF-1 LR3 4℃可保存2-7天，尽快用完。若短期不用，请置于-20℃保存。开启后，请尽快使用，避免污染。 使用限制 仅适于科研、实验室和生产使用，不能直接使用于人体 Product Introduction Insulin like growth factor-1 (IGF-1) is a hormone with a molecular weight of 7.6kd, and its molecular structure is similar to that of insulin.The main mechanism of action of IGF-1 is to induce signaling within the cell by binding to its specific receptor (IGF1R).IGF-1 is one of the most potent activators of the Akt signaling pathway, which, upon activation, stimulates cell growth and proliferation, and inhibits apoptosis.IGF-1 LR3 adds 13 amino acids to the N-terminus of the intact IGF-1 molecule to form 83 amino acid long-chain IGF-1 and replaces the 3rd amino acid of IGF-1 molecule, glutamic acid (E), with arginine (R), so called R3.IGF-1 LR3 has higher stability and bioactivity than IGF-1 without modification. Specification parameters Source Escherichia coli Appearance white lyophilized powder Activity ≥1.0×106IU/mg pH 6.5-7.5 Molecular weight 7.6kD Endotoxin <5EU/mg CAS No 946870-92-4 Matters needing attention Reconstitution: it is recommended to reconstitute the rigf-1 LR3 lyophilized powder to 100-200 UG / ml with sterile water and further dilution with other solvents may be performed.Rigf-1 LR3 dissolved at 4 ° C can be stored for 2-7 days and used up as soon as possible.To not use for short periods, store at - 20 ℃.Use as soon as possible after opening to avoid contamination. Limitations of use It is suitable for research, laboratory and production use only and cannot be used directly in humans |
| 纯度 | ≥90%(SDS-PAGE) |
| pH | 6.5-7.5 |
|---|
| 分子量 | 7.6kD |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 C2308051 |
分析证书 | R283957 |
首页
400-620-6333
