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基本描述
| 英文别名 | Polyasparticacid(PASP) | polyasparticacid | ||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 规格或纯度 | Moligand™ | ||||||||||||||||||||||||||||||||||||||
| 稳定性与储存 | 产品充氩储存、避光、-20℃以下保存。 | ||||||||||||||||||||||||||||||||||||||
| 英文名称 | Poly(L-aspartic acid) | ||||||||||||||||||||||||||||||||||||||
| 储存温度 | 避光,-20°C储存,充氩 | ||||||||||||||||||||||||||||||||||||||
| 运输条件 | 超低温冰袋运输 | ||||||||||||||||||||||||||||||||||||||
| 产品介绍 |
聚-L-天冬氨酸是一种带中性电荷的合成聚氨基酸。 它是一种溶于水的固体。 聚-L-天冬氨酸的应用包括与活性分子结合以提高活性、用于表面涂层的逐层沉积技术、骨矿化和水处理。我们的聚-L-天冬氨酸已经过提纯 通过透析，在0.2um上无菌过滤，冻干，并在Ar下储存。 产品规格参数表:
Poly-L-aspartic acid is a neutral charged synthetic polyamino acid. It is a solid soluble in water. Applications for poly-L-aspartic acid include the conjugation to active molecules for improved activities, the layer-by-layer deposition techniques for surface coating, the mineralization of bone, and the water treatment.Our poly-L-aspartic acid has been purified by dialysis, sterile-filtered on 0.2um, lyophilized, and stored under Ar. Product Specification Reference Number：
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关联靶点（人）
SLC1A1
Tchem
兴奋性氨基酸转运体3(Excitatory amino acid transporter 3)
(0 活性数据)
SLC1A7
Tchem
兴奋性氨基酸转运体5(Excitatory amino acid transporter 5)
(0 活性数据)
SLC1A3
Tchem
兴奋性氨基酸转运体1(Excitatory amino acid transporter 1)
(0 活性数据)
SLC1A6
Tchem
兴奋性氨基酸转运体4(Excitatory amino acid transporter 4)
(0 活性数据)
SLC1A2
Tchem
兴奋性氨基酸转运体2(Excitatory amino acid transporter 2)
(0 活性数据)
F2
Tclin
Thrombin
(11687 活性数据)
CA2
Tclin
Carbonic anhydrase II
(17698 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
ACE
Tclin
Angiotensin-converting enzyme
(1423 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
HTR2B
Tclin
Serotonin 2b (5-HT2b) receptor
(10323 活性数据)
TBXA2R
Tclin
Thromboxane A2 receptor
(5717 活性数据)
PDE4A
Tclin
Phosphodiesterase 4A
(1943 活性数据)
ADORA3
Tchem
Adenosine A3 receptor
(15931 活性数据)
CA1
Tclin
Carbonic anhydrase I
(13240 活性数据)
HRH3
Tclin
Histamine H3 receptor
(10389 活性数据)
ARSA
Tbio
Cerebroside-sulfatase
(655 活性数据)
KDR
Tclin
Vascular endothelial growth factor receptor 2
(20924 活性数据)
GRM6
Tchem
Metabotropic glutamate receptor 6
(361 活性数据)
ALDH1A1
Tchem
Aldehyde dehydrogenase 1A1
(77053 活性数据)
GRM1
Tchem
Metabotropic glutamate receptor 1
(2309 活性数据)
CYP2D6
Tclin
Cytochrome P450 2D6
(33882 活性数据)
SLC1A1
Tchem
Excitatory amino acid transporter 3
(527 活性数据)
SLC1A3
Tchem
Excitatory amino acid transporter 1
(586 活性数据)
CYP1A2
Tchem
Cytochrome P450 1A2
(26471 活性数据)
CYP2C9
Tchem
Cytochrome P450 2C9
(32119 活性数据)
CYP2C19
Tchem
Cytochrome P450 2C19
(29246 活性数据)
CYP3A4
Tclin
Cytochrome P450 3A4
(53859 活性数据)
HEK293
(82097 活性数据)
SLC7A5
Tchem
L-type amino acid transporter 1
(388 活性数据)
APEX1
Tchem
DNA-(apurinic or apyrimidinic site) lyase
(38016 活性数据)
Skin
(286 活性数据)
EHMT2
Tchem
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
(93046 活性数据)
TDP1
Tchem
Tyrosyl-DNA phosphodiesterase 1
(345557 活性数据)
LMNA
Tbio
Prelamin-A/C
(36751 活性数据)
BLM
Tchem
Bloom syndrome protein
(4248 活性数据)
MEN1
Tchem
Menin/Histone-lysine N-methyltransferase MLL
(48157 活性数据)
关联靶点（其它种属）
CA4
Carbonic anhydrase IV (1713 活性数据)
Grm2
Metabotropic glutamate receptor 2 (1326 活性数据)
Hdac6
Histone deacetylase 6 (222 活性数据)
Slc1a2
Excitatory amino acid transporter 2 (39 活性数据)
dapA
Dihydrodipicolinate synthase (65 活性数据)
Canis familiaris (36305 活性数据)
GH4-C1 (8 活性数据)
Jensen sarcoma (11 活性数据)
MH1C1 (8 活性数据)
7800C1 cell line (8 活性数据)
H4 (48 活性数据)
Slc1a6
Excitatory amino acid transporter 4 (71 活性数据)
lef
Anthrax lethal factor (7585 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
Plasma (328 活性数据)
ffp
4'-phosphopantetheinyl transferase ffp (24982 活性数据)
FTL
Ferritin light chain (43324 活性数据)
Grin1
Glutamate NMDA receptor (6467 活性数据)
Slc16a10
Monocarboxylate transporter 10 (73 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
GAP1
General amino-acid permease GAP1 (481 活性数据)
Carbonic anhydrase-like protein, putative (25 活性数据)
Glutamate transporter homolog (3 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | (2S)-2-aminobutanedioic acid |
| INCHI | 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1 |
| InChi Key | CKLJMWTZIZZHCS-REOHCLBHSA-N |
| Smiles | C(C(C(=O)O)N)C(=O)O |
| Isomeric SMILES | C([C@@H](C(=O)O)N)C(=O)O |
| 关联CAS | 181828-06-8 |
| Reaxy-Rn | 774618 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=774618&ln= |
化学和物理性质
| 敏感性 | 对光线敏感 |
|---|---|
| 分子量 | 133.100 g/mol |
| XLogP3 | -2.800 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 5 |
| 可旋转键计数Rotatable Bond Count | 3 |
| 精确质量Exact Mass | 133.038 Da |
| 单同位素质量Monoisotopic Mass | 133.038 Da |
| 拓扑极表面积Topological Polar Surface Area | 101.000 Ų |
| 重原子数Heavy Atom Count | 9 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 133.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 1 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 E2520452 |
分析证书 | P489925 |
| E2520453 |
分析证书 | P489925 |
| E2520473 |
分析证书 | P489925 |
| E2520488 |
分析证书 | P489925 |
| E2520454 |
分析证书 | P489925 |
| E2520455 |
分析证书 | P489925 |
| E2520456 |
分析证书 | P489925 |
| E2520457 |
分析证书 | P489925 |
| E2520654 |
分析证书 | P489925 |
| E2520655 |
分析证书 | P489925 |
| E2520656 |
分析证书 | P489925 |
| E2520657 |
分析证书 | P489925 |
| E2516410 |
分析证书 | P489925 |
| E2516407 |
分析证书 | P489925 |
| E2516408 |
分析证书 | P489925 |
| E2516409 |
分析证书 | P489925 |
| G2410545 |
分析证书 | P489925 |
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此产品的引用文献
引用文献
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| 2. Ying Yang, Liuyan Wei, Weiqin You, Huisha Huang, Shuai Wang, Dandan Hou, Chujun Qin, Zhiheng Su, Mei Li. (2025) A simple colorimetric and paper-based-smartphone sensing platform based on the enhanced peroxidase-like activity of Al doping Prussian blue for point-of-care detection of GSH. TALANTA, 293 (128020). [PMID:40164025] [10.1016/j.talanta.2025.128020] |
| 3. Yuhui Zhu, Hao Gu, Jiawei Yang, Anshuo Li, Lingli Hou, Mingliang Zhou, Xinquan Jiang. (2024) An Injectable silk-based hydrogel as a novel biomineralization seedbed for critical-sized bone defect regeneration. Bioactive Materials, 35 (274). [PMID:38370865] [10.1016/j.bioactmat.2024.01.024] |
| 4. Feifan Cheng, Yue Huang, Danling Mei, Lei Wang, Xueqin Zhao, Biao Huang. (2025) Eu-polyaspartic acid based ratiometric fluorescent probes for ultrasensitive and visual detection of tetracycline and copper ions in food samples. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 137 (106867). [10.1016/j.jfca.2024.106867] |
| 5. Xi Chen, Ying Liu, Sheng-Nan Duan, Ping Wang, Yu-Nan Chen, Min Fu, Rong Liang, Xinxiang Zhang, Huan Shen, Ying-Lin Zhou, Cheng Shi. (2025) LC-MS based untargeted metabolomics reveals benzoic acid as a predictive biomarker for embryo implantation potential. ANALYST, [PMID:40190166] [10.1039/D4AN01552E] |
| 6. Sihua Wu, Jinhui Zou, Baohua Zhang, Jiantian Lu, Guan Rong Lin, Yuwei Zhang, Li Niu. (2025) Oxygen Vacancy-Enriched NiO Nanozymes Achieved by Facile Annealing in Argon for Detection of L-Cys. ANALYST, [PMID:40018863] [10.1039/D5AN00054H] |
| 7. Zhou Mengyan, Zhang Zhihui, Zheng Qi, Yu Mingdi, Si Mengxu, Wu Sirui, Zhang Yanan, Ding Shushu, Fu Ding-Yi. (2025) Ratiometric fluorescence quantification of folic acid utilizing D-penicillamine-based carbon dots in conjunction with glutathione S-transferase-Au nanoclusters. MICROCHIMICA ACTA, 192 (4): (1-13). [PMID:40080078] [10.1007/s00604-025-07062-8] |
| 8. Chen Kun, Ma Chaoqun, Chen Guoqing, Yang Taiqun, Gao Hui, Li Lei, Hu Anqi, Cao Jun, Zheng Chenkai, Ma Longyao, Chen Zehao. (2025) SERS Substrate Based on COFs@Ag for Rapid Detection of Pefloxacin. Plasmonics, (1-9). [10.1007/s11468-025-02935-3] |