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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P489328-25g |
25g |
现货 ![]() |
| |
| P489328-100g |
100g |
现货 ![]() |
| |
| P489328-500g |
500g |
现货 ![]() |
| |
| P489328-2.5kg |
2.5kg |
现货 ![]() |
|
| 别名 | 苄氯菊酯 |
|---|---|
| 英文别名 | 3-(Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate | Stomoxi | Activyl tick plus | Permethrinum | Cyclopropanecarboxylicacid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester,(1R,3S)-rel- |
| 规格或纯度 | ≥95%, cis-trans mixture |
| 英文名称 | Permethrin |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 封闭剂 |
| 作用机制 | 电压敏感钠通道阻滞剂 |
| 产品介绍 |
Permethrin is a widely-used pesticide of the pyrethroid family. Permethrin interacts with voltage-gated Na+ channels and inhibits their natural deactivation, causing the channels to remain open for a long time and destroying equilibrium of the neuronal system. Pyrethroids are also thought to interact with GABA receptors and associated pathways. |
| 纯度 | ≥95% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 258-067-9 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate |
| INCHI | 1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3 |
| InChi Key | RLLPVAHGXHCWKJ-UHFFFAOYSA-N |
| Smiles | CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C |
| Isomeric SMILES | CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C |
| UN Number | 3077 |
| Packing Group | III |
| 分子量 | 391.29 |
| Beilstein号 | 5765325 |
| Reaxy-Rn | 5765325 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5765325&ln= |
| 溶解性 | Soluble in water (Partly miscible), DMSO (40 mg/ml), and ethanol (25 mg/ml). |
|---|---|
| 密度 | 1.19 |
| 折光率 | 1.5627 |
| 沸点 | >290℃(760 torr) |
| 熔点 | 35°C |
| 分子量 | 391.300 g/mol |
| XLogP3 | 6.500 |
| 氢键供体数Hydrogen Bond Donor Count | 0 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 7 |
| 精确质量Exact Mass | 390.079 Da |
| 单同位素质量Monoisotopic Mass | 390.079 Da |
| 拓扑极表面积Topological Polar Surface Area | 35.500 Ų |
| 重原子数Heavy Atom Count | 26 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 521.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 2 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07, GHS09 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H316: 引起轻微皮肤刺激 H317: 可能引起皮肤过敏反应 H410: 对水生生物有剧毒并具有长期持续影响 H302+H332: 吞咽或吸入有害。 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P271: 仅在室外或通风良好的地方使用。 P272: 被污染的工作服不允许离开工作场所 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P330: 漱口 P391: 收集溢出物 P302+P352: 如皮肤沾染:用水充分清洗。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P333+P313: 如发生皮肤刺激或皮疹:求医/就诊。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P501: 将内容物/容器处理到。。。 P301+P317: 如果被吞咽:请寻求医疗帮助。 P317: 寻求紧急医疗救助。 |
| WGK Germany | 3 |
| RTECS | GZ1255000 |
| Class | 9 |
| 个人防护装备 | dust mask type N95 (US),Eyeshields,Faceshields,Gloves |
| 1. Yuyue Zang, Na Hang, Jiale Sui, Senlin Duan, Wanning Zhao, Jing Tao, Songqing Li. (2024) Magnetic Persimmon Leaf Composite: Preparation and Application in Magnetic Solid-Phase Extraction of Pesticides in Water Samples. MOLECULES, 29 (1): (45). [PMID:38202628] [10.3390/molecules29010045] |
| 2. Mingmai Bao, Jiahui Bai, Ying Wang, Suzhen Zhu, Yingchao Liu, Tianlun Wen, Jing Zhang, Shuang-cheng Ma, Yinlong Guo. (2023) Plasma-Excited Nebulizer Gas-Assisted Electrospray Ionization: Enhancing the Sensitivity of Pesticide in Mass Spectrometry. ANALYTICAL CHEMISTRY, 95 (40): (14842–14852). [PMID:37779463] [10.1021/acs.analchem.3c01502] |
| 3. Xuecheng Zhu, Hongfei Su, Huilin Liu, Baoguo Sun. (2023) A selectivity-enhanced fluorescence imprinted sensor based on yellow-emission peptide nanodots for sensitive and visual smart detection of λ-cyhalothrin. ANALYTICA CHIMICA ACTA, 1255 (341124). [PMID:37032054] [10.1016/j.aca.2023.341124] |
| 4. Xiang Xiangmei, Dong Kangyu, Li Zhanjun. (2022) Vector effect of polystyrene film microplastic in enriching Sudan III from natural particles and its burst release into simulated digestive fluid containing fatty acid. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 29 (60): (91155-91164). [PMID:35881288] [10.1007/s11356-022-22218-2] |
| 5. Mao-Ye Li, Yun Wang, Xiao Lei, Chuan-Tao Xu, Dong-Dong Wang, Su Liu, Shi-Guang Li. (2021) Molecular characterization of a catalase gene from the green peach aphid (Myzus persicae). ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 108 (2): (e21835). [PMID:34309077] [10.1002/arch.21835] |
| 6. Yuheng Guo, Wenmin Zhang, Hui Chen, Qingqing Ding, Qingqing Li, Lan Zhang. (2021) In situ fabrication of nitrogen doped graphitic carbon networks coating for high-performance extraction of pyrethroid pesticides. TALANTA, 233 (122542). [PMID:34215045] [10.1016/j.talanta.2021.122542] |
| 7. Kai Tian, Jing Feng, Jiang Zhu, Jiagao Cheng, Mei Li, Xinghui Qiu. (2021) Pyrethrin-resembling pyrethroids are metabolized more readily than heavily modified ones by CYP9As from Helicoverpa armigera. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 176 (104871). [PMID:34119216] [10.1016/j.pestbp.2021.104871] |
| 8. Songqing Li, Wentao Han, Wanning Zhao, Youqing Luo. (2021) Flexible dispersive liquid–liquid microextraction for on-site sample pre-concentration. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, [10.1080/03067319.2019.1665654] |
| 9. Xiao-Chun Ma, Zong-Qin Ma, Meng-Xin Zhao, Ying-Hui Wang, Yuan Peng, Xin Guo, Fang-Huan Wang, Zhe Meng, Hao-Bo Zheng. (2021) Facile synthesis of magnetic molybdenum disulfide@graphene nanocomposite with amphiphilic properties and its application in solid-phase extraction for a wide polarity of insecticides in wolfberry samples. Analytical Methods, 13 (5): (672-684). [PMID:33475104] [10.1039/D0AY01939A] |
| 10. Qiuyan Zhu, Yang Yang, Zhiting Lao, Yingying Zhong, Kun Zhang, Suqing Zhao. (2020) Photodegradation kinetics, mechanism and aquatic toxicity of deltamethrin, permethrin and dihaloacetylated heterocyclic pyrethroids. SCIENCE OF THE TOTAL ENVIRONMENT, 749 (142106). [PMID:33370902] [10.1016/j.scitotenv.2020.142106] |
| 11. Qiuyan Zhu, Yang Yang, Zhiting Lao, Yingying Zhong, Kun Zhang, Suqing Zhao. (2020) Acute and chronic toxicity of deltamethrin, permethrin, and dihaloacetylated heterocyclic pyrethroids in mice. PEST MANAGEMENT SCIENCE, 76 (12): (4210-4221). [PMID:32596996] [10.1002/ps.5978] |
| 12. Qiuyan Zhu, Yang Yang, Zhiting Lao, Yingying Zhong, Bingjie Zhang, Xiping Cui, Paul O'Neill, David Hong, Kun Zhang, Suqing Zhao. (2019) Synthesis, insecticidal activities and resistance in Aedes albopictus and cytotoxicity of novel dihaloacetylated heterocyclic pyrethroids. PEST MANAGEMENT SCIENCE, 76 (2): (636-644). [PMID:31318140] [10.1002/ps.5559] |
| 13. Pang Yachao, Zang Xiaohuan, Wang Mengting, Chang Qingyun, Zhang Shuaihua, Wang Chun, Wang Zhi. (2018) Fibrous boron nitride nanocomposite for magnetic solid phase extraction of ten pesticides prior to the quantitation by gas chromatography. MICROCHIMICA ACTA, 185 (12): (1-7). [PMID:30488359] [10.1007/s00604-018-3103-0] |
| 14. Fang Liu, Xiaoling Yang, Xiaoling Wu, Xuefei Xi, Haixiang Gao, Sanbing Zhang, Wenfeng Zhou, Runhua Lu. (2018) A dispersive magnetic solid phase microextraction based on ionic liquid-coated and cyclodextrin-functionalized magnetic core dendrimer nanocomposites for the determination of pyrethroids in juice samples. FOOD CHEMISTRY, 268 (485). [PMID:30064787] [10.1016/j.foodchem.2018.06.105] |
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| 18. Xiaoling Yang, Panjie Zhang, Xiaobing Li, Lu Hu, Haixiang Gao, Sanbing Zhang, Wenfeng Zhou, Runhua Lu. (2016) Effervescence-assisted β-cyclodextrin/attapulgite composite for the in-syringe dispersive solid-phase extraction of pyrethroids in environmental water samples. TALANTA, 153 (353). [PMID:27130127] [10.1016/j.talanta.2016.03.007] |
| 19. Yu Chen, Zhang Sanbing, Zhang Jiaheng, Li Songqing, Zhou Wenfeng, Gao Haixiang, Lu Runhua. (2013) An in situ ionic liquid dispersive liquid-liquid microextraction method for the detection of pyrethroids by LC-UV in environmental water samples. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 24 (6): (1034-1040). [10.5935/0103-5053.20130133] |
| 20. Shuai Liu, Jingkai Zhao, Junfeng Wu, Ling Wang, Chuanan Yao, Jiandong Hu, Hao Zhang. (2025) A microfluidic paper-based fluorescent sensor integrated with a smartphone platform for rapid on-site detection of omethoate pesticide. FOOD CHEMISTRY, 463 (141205). [PMID:39293375] [10.1016/j.foodchem.2024.141205] |
| 21. Shu Zhu, Shangying Qin, Chonghui Wei, Li Cen, Luyun Xiong, Xingyu Luo, Yilin Wang. (2024) Acetylcholine triggered enzymatic cascade reaction based on Fe7S8 nanoflakes catalysis for organophosphorus pesticides visual detection. ANALYTICA CHIMICA ACTA, (342464). [PMID:38553122] [10.1016/j.aca.2024.342464] |
| 22. Shurong Chen, Min Zhu, Ying Wang, Jinru Ding, Mingji Tan, Jindou Zhao, Jiahan Xie, Zhibing Wang. (2025) Dispersive liquid-liquid microextraction based on temperature-responsive supramolecular solvent followed by HPLC-DAD for the determination of pyrethroid pesticides in tobacco samples. TALANTA, 285 (127350). [PMID:39662221] [10.1016/j.talanta.2024.127350] |
| 23. Pan Tao, Yang Luo, Kai Zheng, Jing Cao, Li Zhu, Xunsi Wang, Wei Zhang, Shixun Dai, Qiushun Zou, Peiqing Zhang. (2025) FTW SERS probes with Ag NCs-GO composite structure excited by evanescent wave for in situ detection of permethrin. ANALYTICA CHIMICA ACTA, (343646). [PMID:39880504] [10.1016/j.aca.2025.343646] |
| 24. Sitian Gu, Wenli Zhu, Yufei Liu, Huixiao Duo, Qingli Yang, Xiudan Hou. (2025) Ionic liquid-modified magnetic covalent organic framework for the extraction of four pyrethroids in traditional Chinese herbs. JOURNAL OF CHROMATOGRAPHY A, 1743 (465719). [PMID:39874742] [10.1016/j.chroma.2025.465719] |
| 25. Afrasyab Khan, Bibimaryam Khan, Shakeel Hussain, Yuhan Wang, Weijun Mai, Yongzhong Hou. (2024) Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress. AQUATIC TOXICOLOGY, 273 (107021). [PMID:38996480] [10.1016/j.aquatox.2024.107021] |
| 26. Tianzhu Guan, Ning Li, Ya Gao, Mingyuan Gao, Qin Hu, Yajun Gao, Lixia Xiao, Zhenquan Yang, Qiaoquan Liu. (2024) Probing the potential mechanism of permethrin exposure on Alzheimer's disease through enantiomer-specific network toxicology, multi-spectroscopic, and docking approaches. CHEMOSPHERE, 369 (143786). [PMID:39586426] [10.1016/j.chemosphere.2024.143786] |