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一氧化氮合酶
PTIO (=2-苯基-4,4,5,5-四甲基咪唑啉-3-氧代-1-氧) [大气中NO和NO2同时测定用稳定自由基试剂]

PTIO (=2-苯基-4,4,5,5-四甲基咪唑啉-3-氧代-1-氧) [大气中NO和NO2同时测定用稳定自由基试剂]

26篇引用文献

COA

级别和纯度:

≥98%(T)

CAS编号: 18390-00-6
分子式: C₁₃H₁₇N₂O₂
分子量: 233.29
MDL号: MFCD00059929
PubChem编号: 2733513
PubChem SID: 504761011

有货

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库存信息

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货号 (SKU)	包装规格	是否现货	价格	数量
P160514-250mg	250mg	现货
P160514-1g	1g	现货

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卡宾 (22) 氧化应激 (50) 自由基 (24)

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基本描述

别名	2-苯基-4,4,5,5-四甲基咪唑啉-3-氧代-1-氧) [大气中NO和NO2同时测定用稳定自由基试剂] \| 4,5-二氢-4,4,5,5-四甲基-2-苯基-1H-咪唑-1-基氧代-1-氧化物 \| 3-氧代-2-苯基-4,4,5,5-四甲基咪唑啉-1-氧 \| 2-苯基-4,4,5,5-四甲基咪唑啉-1-氧代 3-氧化物 \| 2-苯基-4,4,5,5-四甲基咪唑啉-3-氧代-1-氧
英文别名	PTIO \| MFCD00059929 \| 1H-Imidazol-1-yloxy, 4,5-dihydro-4,4,5,5-tetramethyl-2-phenyl-, 3-oxide \| PTIO (2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) \| A5440 \| 4,5-Dihydro-4,4,5,5-tetramethyl-2-phenyl-1H-imidazol-1-yloxy-1-oxide \| 2-phenyl-4,4,5,5
规格或纯度	≥98%(T)
英文名称	PTIO
生化机理	2-苯基-4, 4, 5, 5-四甲基咪唑-1-氧代 3-氧化物 (PTIOs) 衍生物与一氧化氮 (NO) 反应生成相应的的亚氨基氮氧化物 (PTIs) 和二氧化氮 (NO2)。一种稳定的一氧化氮自由基清除剂；不影响 NO 合成酶而影响 NO；对无生物活性有显著抑制活性。
应用	2-苯基-4，4，5，5，-四甲基咪唑啉-1-氧代 3-氧化物 (PTIO) 已被用作一氧化氮 (NO) 清除剂。
储存温度	2-8°C储存
运输条件	冰袋运输
作用类型	抑制剂
产品介绍	2-苯基-4，4，5，5，-四甲基咪唑啉-1-氧代 3-氧化物 (PTIO) 已被用作一氧化氮 (NO) 清除剂。 2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.
纯度	≥98%(T)

关联靶点（人）

TYR Tclin Tyrosinase (717 活性数据)

点击查看靶蛋白信息： TYR

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

PC-12 (7051 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RAW264.7 (28094 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504761011
分子类型	小分子
INCHI	1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
InChi Key	DYUUGILMVYJEHY-UHFFFAOYSA-N
Smiles	CC1(C([N+](=C(N1[O])C2=CC=CC=C2)[O-])(C)C)C
Isomeric SMILES	CC1(C([N+](=C(N1[O])C2=CC=CC=C2)[O-])(C)C)C
PubChem CID	2733513
分子量	233.29
Reaxy-Rn	13743042

化学和物理性质

溶解性	Soluble in methanol.
敏感性	对热敏感；对光线敏感
分子量	233.290 g/mol
XLogP3	1.200
氢键供体数Hydrogen Bond Donor Count	0
氢键受体数Hydrogen Bond Acceptor Count	1
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	233.129 Da
单同位素质量Monoisotopic Mass	233.129 Da
拓扑极表面积Topological Polar Surface Area	33.000 Å²
重原子数Heavy Atom Count	17
形式电荷Formal Charge	0
复杂度Complexity	316.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到13个结果

批号(Lot Number)	证书类型	货号
H2527490	分析证书	P160514
H2527491	分析证书	P160514
F2413193	分析证书	P160514
C2310418	分析证书	P160514
C2310314	分析证书	P160514
C2310326	分析证书	P160514
A2423068	分析证书	P160514
E2529150	分析证书	P160514
E2224092	分析证书	P160514
E2224112	分析证书	P160514
K2204799	分析证书	P160514
K2428173	分析证书	P160514
D2213021	分析证书	P160514

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