基本描述

别名	苯丙氨酸-苯丙氨酸 \| 二-L-苯丙氨酸 \| (S)-2-[(S)-2-氨基-3-苯基丙酰胺]-3-苯丙酸 \| L-苯丙氨酸-L-苯丙氨酸
英文别名	(2S)-2-{[(2S)-2-amino-3-phenylpropanoyl]amino}-3-phenylpropanoic acid \| AS-18242 \| MFCD00063154 \| FF \| AKOS015919869 \| L-Phe-L-Phe \| AKOS004123341 \| (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-3-phenyl-propionic acid \| P2580 \| s12216 \| AMY22224 \| Phenylal
规格或纯度	≥98%
英文名称	L-Phenylalanyl-L-phenylalanine
储存温度	-20°C储存
运输条件	超低温冰袋运输
产品介绍	Product Application： Evaporating 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) solutions containing diphenylalanine forms nanotubes. These structures have been used for casting silver nanowires, the dipeptide is removed from the wires by enzymatic degradation
纯度	≥98%

关联靶点（人）

TACR1 Tclin Neurokinin 1 receptor (6273 活性数据)

点击查看靶蛋白信息： TACR1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 活性数据)

点击查看靶蛋白信息： SLC15A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488195940
EC号	219-930-5
分子类型	小分子
IIUPAC Name	(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoic acid
INCHI	1S/C18H20N2O3/c19-15(11-13-7-3-1-4-8-13)17(21)20-16(18(22)23)12-14-9-5-2-6-10-14/h1-10,15-16H,11-12,19H2,(H,20,21)(H,22,23)/t15-,16-/m0/s1
InChi Key	GKZIWHRNKRBEOH-HOTGVXAUSA-N
Smiles	C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)O)N
Isomeric SMILES	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)N
分子量	312.36
Reaxy-Rn	2818639
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2818639&ln=

化学和物理性质

溶解性	Soluble at 50mg/ml in 80% acetic acid
敏感性	对热敏感
比旋光度	45° (C=2,AcOH)
熔点	315 °C
分子量	312.400 g/mol
XLogP3	-0.800
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	7
精确质量Exact Mass	312.147 Da
单同位素质量Monoisotopic Mass	312.147 Da
拓扑极表面积Topological Polar Surface Area	92.400 Å²
重原子数Heavy Atom Count	23
形式电荷Formal Charge	0
复杂度Complexity	388.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	2
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	3
个人防护装备	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到11个结果

批号(Lot Number)	证书类型	货号
I2525761	分析证书	P121410
I2525762	分析证书	P121410
I2525763	分析证书	P121410
I2518418	分析证书	P121410
B2518645	分析证书	P121410
C2301730	分析证书	P121410
C2301731	分析证书	P121410
C2301732	分析证书	P121410
C2301733	分析证书	P121410
C2301734	分析证书	P121410
A2513336	分析证书	P121410

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此产品的引用文献

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引用文献

1. D J Kempf,E de Lara,H H Stein,J Cohen,D A Egan,J J Plattner. (1990-01-01) Renin inhibitors based on dipeptide analogues. Incorporation of the hydroxyethylene isostere at the P2/P3 sites.. Journal of medicinal chemistry, 33 ((1)): (371-374). [PMID:2404121]
2. D Peyton,E Breslow. (1985-05-16) Use of perdeuterated peptides in NMR studies of neurophysin-hormone interaction: demonstration of peptide-specific changes in neurophysin resonances.. Biochemical and biophysical research communications, 128 ((3)): (1211-1218). [PMID:4004858]
3. M Dizdaroglu,E Gajewski,M G Simic. (1984-03-01) Enzymatic digestibility of peptides cross-linked by ionizing radiation.. International journal of radiation biology and related studies in physics, chemistry, and medicine, 45 ((3)): (283-295). [PMID:6143737]
4. T Nishihata,T Higuchi,A Kamada. (1984-01-30) Possible mechanism of uptake for several compounds in ionized form through human erythrocyte membrane.. Life sciences, 34 ((5)): (427-436). [PMID:6694531]
5. G B Dreyer,J C Boehm,B Chenera,R L DesJarlais,A M Hassell,T D Meek,T A Tomaszek,M Lewis. (1993-01-26) A symmetric inhibitor binds HIV-1 protease asymmetrically.. Biochemistry, 32 ((3)): (937-947). [PMID:8422397]
6. H Mozsolits,T H Lee,H J Wirth,P Perlmutter,M I Aguilar. (1999-08-31) The interaction of bioactive peptides with an immobilized phosphatidylcholine monolayer.. Biophysical journal, 77 ((3)): (1428-1444). [PMID:10465754]
7. S Sabbah,F Süss,G K Scriba. (2001-10-09) pH-dependence of complexion constants and complex mobility in capillary electrophoresis separations of dipeptide enantiomers.. Electrophoresis, 22 ((15)): (3163-3170). [PMID:11589275]
8. Meital Reches,Ehud Gazit. (2003-04-26) Casting metal nanowires within discrete self-assembled peptide nanotubes.. Science (New York, N.Y.), 300 ((5619)): (625-627). [PMID:12714741]
9. Claudia Huber,Wolfgang Eisenreich,Stefan Hecht,Gunter Wächtershäuser. (2003-08-16) A possible primordial peptide cycle.. Science (New York, N.Y.), 301 ((5635)): (938-940). [PMID:12920291]
10. Meital Reches,Ehud Gazit. (2006-04-04) Designed aromatic homo-dipeptides: formation of ordered nanostructures and potential nanotechnological applications.. Physical biology, 3 ((1)): (S10-S19). [PMID:16582461]
11. Sten O Nilsson Lill. (2010-07-09) Evaluation of dispersion-corrected density functional theory (B3LYP-DCP) for compounds of biochemical interest.. Journal of molecular graphics & modelling, 29 ((2)): (178-187). [PMID:20609606]
12. Dmitriy Berillo,Bo Mattiasson,Igor Yu Galaev,Harald Kirsebom. (2011-12-02) Formation of macroporous self-assembled hydrogels through cryogelation of Fmoc-Phe-Phe.. Journal of colloid and interface science, 368 ((1)): (226-230). [PMID:22129632]
13. Christiane Lütticke,Patrick Hauske,Urs Lewandrowski,Albert Sickmann,Markus Kaiser,Michael Ehrmann. (2012-04-12) E. coli LoiP (YggG), a metalloprotease hydrolyzing Phe-Phe bonds.. Molecular bioSystems, 8 ((6)): (1775-1782). [PMID:22491786]
14. Rebecca Fransson,Christian Sköld,Jadel M Kratz,Richard Svensson,Per Artursson,Fred Nyberg,Mathias Hallberg,Anja Sandström. (2013-06-06) Constrained H-Phe-Phe-NH2 analogues with high affinity to the substance P 1-7 binding site and with improved metabolic stability and cell permeability.. Journal of medicinal chemistry, 56 ((12)): (4953-4965). [PMID:23735006]
15. Alice B Nongonierma,Mehdeeyah Lalmahomed,Sara Paolella,Richard J FitzGerald. (2017-04-30) Milk protein isolate (MPI) as a source of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides.. Food chemistry, 231 (202-211). [PMID:28449998]
16. Jacek Szczerbiński,Jonas B Metternich,Guillaume Goubert,Renato Zenobi. (2020-01-03) How Peptides Dissociate in Plasmonic Hot Spots.. Small (Weinheim an der Bergstrasse, Germany), 16 ((4)): (e1905197-e1905197). [PMID:31894644]
17. C R Shoaf,W D Heizer,M Caplow. (1980-08-14) Uptake of the components of phenylalanylphenylalanine and maltose by intestinal epithelium.. Biochimica et biophysica acta, 600 ((3)): (939-949). [PMID:7407152]
18. Natalia Sánchez de Groot,Teodor Parella,Francesc X Aviles,Josep Vendrell,Salvador Ventura. (2006-12-19) Ile-phe dipeptide self-assembly: clues to amyloid formation.. Biophysical journal, 92 ((5)): (1732-1741). [PMID:17172307]
19. Robert C Dunbar,Jeffrey D Steill,Jos Oomens. (2011-01-05) Chirality-induced conformational preferences in peptide-metal ion binding revealed by IR spectroscopy.. Journal of the American Chemical Society, 133 ((5)): (1212-1215). [PMID:21192647]
20. Aseem Mishra,Virander Singh Chauhan. (2011-01-12) Probing the role of aromaticity in the design of dipeptide based nanostructures.. Nanoscale, 3 ((3)): (945-949). [PMID:21221462]
21. Amy F Roth,Irene Papanayotou,Nicholas G Davis. (2011-06-10) The yeast kinase Yck2 has a tripartite palmitoylation signal.. Molecular biology of the cell, 22 ((15)): (2702-2715). [PMID:21653825]
22. Gokhan Demirel,Fatih Buyukserin. (2011-09-02) Surface-induced self-assembly of dipeptides onto nanotextured surfaces.. Langmuir : the ACS journal of surfaces and colloids, 27 ((20)): (12533-12538). [PMID:21879773]
23. Xinming Li,Yi Kuang,Hsin-Chieh Lin,Yuan Gao,Junfeng Shi,Bing Xu. (2011-09-29) Supramolecular nanofibers and hydrogels of nucleopeptides.. Angewandte Chemie (International ed. in English), 50 ((40)): (9365-9369). [PMID:21948432]
24. Nidhi Gour,Chandra Kanth P,Bharti Koshti,Vivekshinh Kshtriya,Dhruvi Shah,Sunita Patel,Reena Agrawal-Rajput,Manoj K Pandey. (2018-11-02) Amyloid-like Structures Formed by Single Amino Acid Self-Assemblies of Cysteine and Methionine.. ACS chemical neuroscience, 10 ((3)): (1230-1239). [PMID:30380833]
25. Rongchun Zhang,You-Lee Hong,Thirupathi Ravula,Yusuke Nishiyama,Ayyalusamy Ramamoorthy. (2020-04-03) High-resolution proton-detected MAS experiments on self-assembled diphenylalanine nanotubes enabled by fast MAS and high magnetic field.. Journal of magnetic resonance (San Diego, Calif. : 1997), 313 (106717-106717). [PMID:32240957]
26. Giuseppe Trapani,Viviana Carmela Linda Caruso,Lorena Maria Cucci,Francesco Attanasio,Giovanni Tabbì,Giuseppe Forte,Diego La Mendola,Cristina Satriano. (2020-05-28) Graphene Oxide Nanosheets Tailored With Aromatic Dipeptide Nanoassemblies for a Tuneable Interaction With Cell Membranes.. Frontiers in bioengineering and biotechnology, 8 (427-427). [PMID:32457892]
27. Changjun Hu, Zhenkun Mao, Zhentao Li, Qiaoyan Li, Zilin Chen. (2021) Benzoic acid-modified monolithic column for separation of hydrophilic compounds by capillary electrochromatography with high content of water in mobile phase. JOURNAL OF CHROMATOGRAPHY A, 1647 (462166). [PMID:33957344] [10.1016/j.chroma.2021.462166]

溶液计算器

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复溶计算器

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所需的复溶浓度

货号 (SKU)	包装规格	是否现货
P121410-250mg	250mg	现货
P121410-1g	1g	现货
P121410-5g	5g	现货
P121410-25g	25g	现货

L-苯丙氨酰-L-苯丙氨酸

库存信息

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

显示更多⌵

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器