| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P114481-250mg |
250mg |
现货  |
|
| 别名 | 2-(环己基羰基)-1,2,3,6,7-11b-六氢-4H-吡嗪并(2,1a)异喹啉-4-酮 |
|---|---|
| 英文别名 | Droncit | Praziquantel Tablets | cid_4891 | NSC 757285 | Praziquantel-(cyclohexyl-d11) | 5-24-03-00361 (Beilstein Handbook Reference) | Bay-8440 | DTXCID501182 | MFCD00058531 | Praziquantel Injection | Prestwick1_000260 | Spectrum4_000482 | 2-cyclohexanec |
| 规格或纯度 | 分析标准品 |
| 英文名称 | Praziquantel |
| 应用 | A highly effective anthelmintic |
| 运输条件 | 常规运输 |
| 作用类型 | 封闭剂 |
| 作用机制 | 电压活化钙通道 beta 2 亚基阻滞剂 |
| 产品介绍 |
Praziquantel is a highly effective anthelmintic against all Schistosoma species.A highly effective anthelmintic Praziquantel is a highly effective anthelmintic against all Schistosoma species. |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 259-559-6 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one |
| INCHI | 1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2 |
| InChi Key | FSVJFNAIGNNGKK-UHFFFAOYSA-N |
| Smiles | C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 |
| Isomeric SMILES | C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 |
| 分子量 | 312.41 |
| Beilstein号 | 761557 |
| Reaxy-Rn | 761557 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=761557&ln= |
| 溶解性 | Soluble in 100% ethanol or chloroform; slightly soluble in water. |
|---|---|
| 密度 | 1.22 |
| 熔点 | 136-138°C |
| 分子量 | 312.400 g/mol |
| XLogP3 | 2.700 |
| 氢键供体数Hydrogen Bond Donor Count | 0 |
| 氢键受体数Hydrogen Bond Acceptor Count | 2 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 312.184 Da |
| 单同位素质量Monoisotopic Mass | 312.184 Da |
| 拓扑极表面积Topological Polar Surface Area | 40.600 Ų |
| 重原子数Heavy Atom Count | 23 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 472.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 1 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H302: 吞食有害 H412: 对水生生物有害并具有长期持续影响 |
| 预防措施声明 |
P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P273: 避免释放到环境中。 P330: 漱口 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。 P501: 将内容物/容器处理到。。。 |
| WGK Germany | 1 |
| RTECS | UQ4150000 |
| Merck Index | 7716 |
| 个人防护装备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 C1801032 |
分析证书 | P114481 |
| 1. Jieqing Feng, Qisheng Zhong, Ting Zhou. (2022) Online Pressure Change Focusing-Supercritical Fluid Selective Extraction Chromatography for Analyzing Chiral Drugs in Microliter-Scale Plasma Samples. ANALYTICAL CHEMISTRY, 94 (46): (16222–16230). [PMID:36356211] [10.1021/acs.analchem.2c03892] |
| 2. Xiao Tu, Chenxi Duan, Siwei Wu, Shengli Fu, Jianmin Ye. (2021) Identification of plumbagin as an effective chemotherapeutic agent for treatment of Gyrodactylus infections. AQUACULTURE, 535 (736372). [10.1016/j.aquaculture.2021.736372] |
| 3. Renjie Hui, Yueying Gao, Jingyi Liu, Haili Liu, Chunlei Tang, Bainian Feng. (2019) Determination of an isonicotinylhydrazide derivative, a novel positive inotropic compound, in mouse plasma by LC–MS/MS and its application to a pharmacokinetics study. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 165 (12). [PMID:30496986] [10.1016/j.jpba.2018.10.034] |
| 4. Qiang LI, Yuan-Yuan LI, Nan ZHU, Zhu-Xian GAO, Tian-Jun LI, Tong ZHOU, Yu-Long MA. (2018) Preparation of Cyclodextrin Type Stationary Phase Based on Graphene Oxide and Its Application in Enantioseparation and Hydrophilic Interaction Chromatography. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 46 (1455). [10.1016/S1872-2040(18)61111-9] |
| 5. Xiao Tu, Jiaxin Hu, Jinghao Peng, Qihan Chen, Yangle Zhao, Zemao Gu. (2025) Discovery of thymoquinone analogues with high anthelmintic activity against monogenean infections in goldfish (Carassius auratus). VETERINARY PARASITOLOGY, 334 (110401). [PMID:39837239] [10.1016/j.vetpar.2025.110401] |
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