首页
化学和生化试剂
砌块
L-(-)-3-苯乳酸, HCA 3 受体激动剂

L-(-)-3-苯乳酸, HCA 3 受体激动剂

1篇引用文献

COA

级别和纯度:

Moligand™

≥98%

CAS编号: 20312-36-1
分子式: C₉H₁₀O₃
分子量: 166.17
Beilstein号: 2209792
EC号: 243-726-5
MDL号: MFCD00004244
PubChem编号: 444718
PubChem SID: 504758831

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
P102441-1g	1g	现货
P102441-5g	5g	现货
P102441-25g	25g	现货
P102441-100g	100g	现货

查看相关系列

HCA3 receptor Agonist (12) 手性非杂环砌块 (288) 羧酸 (2181)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

别名	(S)-(-)-3-苯乳酸 \| (S)-(-)-3-苯基乳酸 \| L-3-苯基乳酸 \| (S)-2-羟基-3-苯基丙酸
英文别名	(S)-(−)-3-Phenyllactic acid \| (S)-2-Hydroxy-3-phenylpropionic acid \| L-3-Phenyllactic acid
规格或纯度	Moligand™, ≥98%
英文名称	L-(-)-3-Phenyllactic acid
储存温度	2-8°C储存
运输条件	冰袋运输
作用类型	激动剂
作用机制	HCA 3 受体激动剂
产品介绍	L -(-)-3-苯乳酸已用于可降解自组装缩肽纳米纤维的开发。 L-(-)-3-Phenyllactic acid has been used in the development of degradable self-assembling depsipeptide nanofibers.
纯度	≥98%

关联靶点（人）

HCAR3 Tchem 羟基羧酸受体 3(Hydroxycarboxylic acid receptor 3) (0 活性数据)

点击查看靶蛋白信息： HCAR3

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

名称和识别符

PubChem SID	504758831
EC号	243-726-5
分子类型	小分子
IIUPAC Name	(2S)-2-hydroxy-3-phenylpropanoic acid
INCHI	1S/C9H10O3/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12)/t8-/m0/s1
InChi Key	VOXXWSYKYCBWHO-QMMMGPOBSA-N
Smiles	C1=CC=C(C=C1)CC(C(=O)O)O
Isomeric SMILES	C1=CC=C(C=C1)C[C@@H](C(=O)O)O
分子量	166.17
Beilstein号	2209792
Reaxy-Rn	2209791
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2209791&ln=

化学和物理性质

溶解性	Solubility in water gives very faint turbidity.
密度	1.265
比旋光度	-20.0 to -22.0 deg(C=2, H2O)
熔点	123-125°C
分子量	166.170 g/mol
XLogP3	1.100
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	166.063 Da
单同位素质量Monoisotopic Mass	166.063 Da
拓扑极表面积Topological Polar Surface Area	57.500 Å²
重原子数Heavy Atom Count	12
形式电荷Formal Charge	0
复杂度Complexity	150.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H319: 引起严重眼睛刺激
预防措施声明	P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。
WGK Germany	3
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到19个结果

批号(Lot Number)	证书类型	货号
L2103648	分析证书	P102441
L2103649	分析证书	P102441
F2517444	分析证书	P102441
F2517445	分析证书	P102441
F2517446	分析证书	P102441
F2517447	分析证书	P102441
C1729080	分析证书	P102441
I2412521	分析证书	P102441
I2412537	分析证书	P102441
C2429661	分析证书	P102441
C2429659	分析证书	P102441
C2429660	分析证书	P102441
B2429426	分析证书	P102441
B2429428	分析证书	P102441
B2429429	分析证书	P102441
B2429434	分析证书	P102441
B2429427	分析证书	P102441
L1811211	分析证书	P102441
J2317071	分析证书	P102441

显示更多⌵

可替换产品

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Peters A, Krumbholz P, Jäger E, Heintz-Buschart A, Çakir MV, Rothemund S, Gaudl A, Ceglarek U, Schöneberg T, Stäubert C. (2019) Metabolites of lactic acid bacteria present in fermented foods are highly potent agonists of human hydroxycarboxylic acid receptor 3.. PLoS Genet, 15 (5): (e1008145). [PMID:31120900]
2. H Peck,R J Pollitt. (1979-06-15) The occurrence of gamma-glutamylphenylalanine in the urine of newborn phenylketonurics.. Clinica chimica acta; international journal of clinical chemistry, 94 ((3)): (237-240). [PMID:466810]
3. P C Clemens,M H Schünemann,G F Hoffmann,A Kohlschütter. (1990-01-01) Plasma concentrations of phenyllactic acid in phenylketonuria.. Journal of inherited metabolic disease, 13 ((2)): (227-228). [PMID:2116554]
4. U Langenbeck,A Behbehani,H Luthe. (1981-01-01) Renal transport of aromatic acids in patients with phenylketonuria.. Journal of inherited metabolic disease, 4 ((2)): (69-70). [PMID:6790852]
5. E Mönch,J Kneer,C Jakobs,M Arnold,H Diehl,U Batzler. (1990-01-01) Examination of urine metabolites in the newborn period and during protein loading tests at 6 months of age--Part 1.. European journal of pediatrics, 149 Suppl 1 (S17-S24). [PMID:2091926]
6. T L Perry,S Hansen. (1981-11-25) Cystinylglycine in plasma: diagnostic relevance for pyroglutamic acidemia, homocystinuria, and phenylketonuria.. Clinica chimica acta; international journal of clinical chemistry, 117 ((1)): (7-12). [PMID:7333014]
7. Chunhui Deng,Chunqing Shang,Yaoming Hu,Xiangmin Zhang. (2002-07-09) Rapid diagnosis of phenylketonuria and other aminoacidemias by quantitative analysis of amino acids in neonatal blood spots by gas chromatography-mass spectrometry.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 775 ((1)): (115-120). [PMID:12101068]
8. Demao Li,Congfa Li,Sixin Liu,Limei Chen. (2005-02-17) [Chiral separation of 3-phenyllactic acid by capillary electrophoresis].. Se pu = Chinese journal of chromatography, 22 ((3)): (281-283). [PMID:15712919]
9. M M Finney,D A Danehower,J D Burton. (2005-03-30) Gas chromatographic method for the analysis of allelopathic natural products in rye (Secale cereale L.).. Journal of chromatography. A, 1066 ((1-2)): (249-253). [PMID:15794579]
10. Katrin Ström,Johan Schnürer,Petter Melin. (2005-05-05) Co-cultivation of antifungal Lactobacillus plantarum MiLAB 393 and Aspergillus nidulans, evaluation of effects on fungal growth and protein expression.. FEMS microbiology letters, 246 ((1)): (119-124). [PMID:15869970]
11. Peter Jeschke,Jordi Benet-Buchholz,Achim Harder,Winfried Etzel,Michael Schindler,Wolfgang Gau,Hans-Christoph Weiss. (2006-06-20) Synthesis and anthelmintic activity of substituted (R)-phenyllactic acid containing cyclohexadepsipeptides.. Bioorganic & medicinal chemistry letters, 16 ((16)): (4410-4415). [PMID:16781154]
12. Emanuele Armaforte,Simone Carri,Giovanni Ferri,Maria Fiorenza Caboni. (2006-09-12) High-performance liquid chromatography determination of phenyllactic acid in MRS broth.. Journal of chromatography. A, 1131 ((1-2)): (281-284). [PMID:16963056]
13. Xingfeng Li,Bo Jiang,Beilei Pan. (2007-03-03) Biotransformation of phenylpyruvic acid to phenyllactic acid by growing and resting cells of a Lactobacillus sp.. Biotechnology letters, 29 ((4)): (593-597). [PMID:17333468]
14. Helena Lind,Jörgen Sjögren,Suresh Gohil,Lennart Kenne,Johan Schnürer,Anders Broberg. (2007-04-26) Antifungal compounds from cultures of dairy propionibacteria type strains.. FEMS microbiology letters, 271 ((2)): (310-315). [PMID:17456184]
15. L H Elvers,J G Loeber,J-L Dhondt,M Fukushi,W H Hannon,T Torresani,D Webster. (2007-06-19) First ISNS Reference Preparation for Neonatal Screening for thyrotropin, phenylalanine and 17alpha-hydroxyprogesterone in blood spots.. Journal of inherited metabolic disease, 30 ((4)): (609-609). [PMID:17574536]
16. Xingfeng Li,Bo Jiang,Beilei Pan,Wanmeng Mu,Tao Zhang. (2008-03-13) Purification and partial characterization of Lactobacillus species SK007 lactate dehydrogenase (LDH) catalyzing phenylpyruvic acid (PPA) conversion into phenyllactic acid (PLA).. Journal of agricultural and food chemistry, 56 ((7)): (2392-2399). [PMID:18333614]
17. Alemu Tekewe,Sawraj Singh,Manpreet Singh,Utpal Mohan,U C Banerjee. (2008-03-29) Development and validation of HPLC method for the resolution of drug intermediates: DL-3-Phenyllactic acid, DL-O-acetyl-3-phenyllactic acid and (+/-)-mexiletine acetamide enantiomers.. Talanta, 75 ((1)): (239-245). [PMID:18371874]
18. Wanmeng Mu,Fengli Liu,Jianghua Jia,Chao Chen,Tao Zhang,Bo Jiang. (2009-06-09) 3-Phenyllactic acid production by substrate feeding and pH-control in fed-batch fermentation of Lactobacillus sp. SK007.. Bioresource technology, 100 ((21)): (5226-5229). [PMID:19501505]
19. Mariana-Carmen Chifiriuc,Lia-Mara Diţu,Otilia Banu,Coralia Bleotu,Olguţa Drăcea,Marcela Bucur,Cristina Larion,Anca Michaela Israil,Veronica Lazăr. (2009-06-11) Subinhibitory concentrations of phenyl lactic acid interfere with the expression of virulence factors in Staphylococcus aureus and Pseudomonas aeruginosa clinical strains.. Roumanian archives of microbiology and immunology, 68 ((1)): (27-33). [PMID:19507624]
20. Mariana-Carmen Chifiriuc,Coralia Bleotu,Lia-Mara Ditu,Diana Smarandache,Elena Săsărman,Otilia Banu,Olguţa Drăcea,Cristina Larion,Lazăr Veronica. (2009-06-11) In vivo experimental model for the study of the influence of subinhibitory concentrations of phenyllactic acid on Staphylococcus aureus pathogenicity.. Roumanian archives of microbiology and immunology, 68 ((1)): (34-37). [PMID:19507625]
21. Jianghua Jia,Wanmeng Mu,Tao Zhang,Bo Jiang. (2009-09-24) Bioconversion of phenylpyruvate to phenyllactate: gene cloning, expression, and enzymatic characterization of D- and L1-lactate dehydrogenases from Lactobacillus plantarum SK002.. Applied biochemistry and biotechnology, 162 ((1)): (242-251). [PMID:19774350]
22. Patrycja Puchalska,Elfriede Pittler,Marek Trojanowicz,Gerald Gübitz,Martin G Schmid. (2010-04-28) Enantioseparation of amino acids and alpha-hydroxy acids on ligand-exchange continuous beds by capillary electrochromatography.. Electrophoresis, 31 ((9)): (1517-1520). [PMID:20422630]
23. C L Gerez,M S Carbajo,G Rollán,G Torres Leal,G Font de Valdez. (2010-08-21) Inhibition of citrus fungal pathogens by using lactic acid bacteria.. Journal of food science, 75 ((6)): (M354-M359). [PMID:20722936]
24. Dora Ndagano,Thibaut Lamoureux,Carine Dortu,Sophie Vandermoten,Philippe Thonart. (2011-07-07) Antifungal activity of 2 lactic acid bacteria of the\u2002Weissella\u2002genus isolated from food.. Journal of food science, 76 ((6)): (M305-M311). [PMID:21729073]
25. Soumen K Manna,Andrew D Patterson,Qian Yang,Kristopher W Krausz,Jeffrey R Idle,Albert J Fornace,Frank J Gonzalez. (2011-07-14) UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model.. Journal of proteome research, 10 ((9)): (4120-4133). [PMID:21749142]
26. Wanmeng Mu,Shuhuai Yu,Bo Jiang,Xingfeng Li. (2012-01-21) Characterization of D-lactate dehydrogenase from Pediococcus acidilactici that converts phenylpyruvic acid into phenyllactic acid.. Biotechnology letters, 34 ((5)): (907-911). [PMID:22261863]
27. Shuhuai Yu,Houyi Jiang,Bo Jiang,Wanmeng Mu. (2012-04-10) Characterization of D-lactate dehydrogenase producing D-3-phenyllactic acid from Pediococcus pentosaceus.. Bioscience, biotechnology, and biochemistry, 76 ((4)): (853-855). [PMID:22484960]
28. M Lakshmi Prasuna,Md Mujahid,Ch Sasikala,Ch V Ramana. (2012-04-13) L-Phenylalanine catabolism and L-phenyllactic acid production by a phototrophic bacterium, Rubrivivax benzoatilyticus JA2.. Microbiological research, 167 ((9)): (526-531). [PMID:22494897]
29. Ganapati D Yadav,Sandip V Pawar. (2012-06-05) Insight into microwave irradiation and enzyme catalysis in enantioselective resolution of DL-(±)-3-phenyllactic acid.. Applied microbiology and biotechnology, 96 ((1)): (69-79). [PMID:22660769]
30. Noelia Rodríguez-Pazo,José Manuel Salgado,Sandra Cortés-Diéguez,José Manuel Domínguez. (2013-02-19) Biotechnological production of phenyllactic acid and biosurfactants from trimming vine shoot hydrolyzates by microbial coculture fermentation.. Applied biochemistry and biotechnology, 169 ((7)): (2175-2188). [PMID:23417349]
31. Jie Xu,Irini Lazou Ahrén,Olena Prykhodko,Crister Olsson,Siv Ahrné,Göran Molin. (2013-05-22) Intake of Blueberry Fermented by Lactobacillus plantarum Affects the Gut Microbiota of L-NAME Treated Rats.. Evidence-based complementary and alternative medicine : eCAM, 2013 (809128-809128). [PMID:23690854]
32. Xuepeng Wang,Yong Wang,Yifan Wu,Yin Xiao. (2019-03-06) A highly sensitive and versatile chiral sensor based on a top-gate organic field effect transistor functionalized with thiolated β-cyclodextrin.. The Analyst, 144 ((8)): (2611-2617). [PMID:30834396]
33. Ling Li,Shuai Zhu,Wenjie Shu,Yueshuai Guo,Yusheng Guan,Juan Zeng,Haichao Wang,Longsen Han,Jiaqi Zhang,Xiaohui Liu,Chunling Li,Xiaojing Hou,Min Gao,Juan Ge,Chao Ren,Hao Zhang,Tim Schedl,Xuejiang Guo,Minjian Chen,Qiang Wang. (2020-10-18) Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation.. Molecular cell, 80 ((3)): (525-540). [PMID:33068521]
34. Danilo Christen,Manuel Tharin,Sandrine Perrin-Cherioux,Eliane Abou-Mansour,Raphaël Tabacchi,Geneviève Défago. (2005-09-01) Transformation of Eutypa dieback and esca disease pathogen toxins by antagonistic fungal strains reveals a second detoxification pathway not present in Vitis vinifera.. Journal of agricultural and food chemistry, 53 ((18)): (7043-7051). [PMID:16131109]
35. Wanmeng Mu,Shuhuai Yu,Lanjun Zhu,Tao Zhang,Bo Jiang. (2012-07-12) Recent research on 3-phenyllactic acid, a broad-spectrum antimicrobial compound.. Applied microbiology and biotechnology, 95 ((5)): (1155-1163). [PMID:22782253]
36. Ye F Tian,Gregory A Hudalla,Huifang Han,Joel H Collier. (2013-11-14) Controllably degradable β-sheet nanofibers and gels from self-assembling depsipeptides.. Biomaterials science, 1 ((10)): [PMID:24224082]
37. Rui Cai, Linlin Gao, Yuxiang Zhang, Lu Cui, Yahong Yuan, Zhouli Wang, Tianli Yue. (2025) Inactivation activity and mechanism of natural antimicrobial agents against Alicyclobacillus spp. in apple juice. FOOD CONTROL, 171 (111119). [10.1016/j.foodcont.2024.111119]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度