| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| N609067-5mg |
5mg |
期货  |
| |
| N609067-25mg |
25mg |
期货 |
|
| 别名 | N-(2-苄氨基)-2-氧代乙基)-N-(4-羟基氨基甲酰基苄基)-4-异丙基苯甲酰胺 |
|---|---|
| 英文别名 | compound 2h |
| 规格或纯度 | Moligand™ |
| 英文名称 | N-(2-(benzylamino)-2-oxoethyl)-N-(4-(hydroxycarbamoyl)benzyl)-4-isopropylbenzamide |
| 作用机制 | 恶性疟原虫组蛋白去乙酰化酶 1 |
| IIUPAC Name | N-(2-(benzylamino)-2-oxoethyl)-N-(4-(hydroxycarbamoyl)benzyl)-4-isopropylbenzamide |
|---|---|
| INCHI | 1S/C27H29N3O4/c1-19(2)22-12-14-24(15-13-22)27(33)30(17-21-8-10-23(11-9-21)26(32)29-34)18-25(31)28-16-20-6-4-3-5-7-20/h3-15,19,34H,16-18H2,1-2H3,(H,28,31)(H,29,32) |
| InChi Key | REDUQXCPUSNJOL-UHFFFAOYSA-N |
| Smiles | ONC(=O)c1ccc(cc1)CN(C(=O)c1ccc(cc1)C(C)C)CC(=O)NCc1ccccc1 |
| PubChem CID | 145996529 |
| 1. Mackwitz MKW, Hesping E, Antonova-Koch Y, Diedrich D, Woldearegai TG, Skinner-Adams T, Clarke M, Schöler A, Limbach L, Kurz T et al.. (2019) Structure-Activity and Structure-Toxicity Relationships of Peptoid-Based Histone Deacetylase Inhibitors with Dual-Stage Antiplasmodial Activity.. ChemMedChem, 14 (9): (912-926). [PMID:30664827] |
| 2. Koehne E, Kreidenweiss A, Zoleko Manego R, McCall M, Mombo-Ngoma G, Mackwitz MKW, Hansen FK, Held J. (2019) Histone deacetylase inhibitors with high in vitro activities against Plasmodium falciparum isolates collected from Gabonese children and adults.. Sci Rep, 9 (1): (17336). [PMID:31758015] |
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