计算溶液所需的质量、体积或浓度。
This is a demo store. No orders will be fulfilled.
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| N476195-25g |
25g |
期货 ![]() |
|
| 别名 | N-十二烷酰基-N-甲基甘氨酸 钠盐 | 肌氨酰 NL | 月桂酰肌氨酸钠 |
|---|---|
| 英文别名 | Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, monohydrochloride | Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt | SODIUM N-LAUROYL SARCOSINATE | N-Lauroylsarcosine, sodium salt | MEDIALAN |
| 规格或纯度 | UltraBio™, 分子生物学级, 超纯级, ≥99%(HPLC) |
| 英文名称 | N-Lauroylsarcosine sodium salt |
| 储存温度 | 室温 |
| 运输条件 | 常规运输 |
| 备注 | 阴离子表面活性剂。 |
| 产品介绍 |
N-月桂酰肌氨酸钠盐适用于需要严格控制元素含量的工艺。该产品有助于膜蛋白、糖蛋白的溶解和分离,以及 RNA 和质粒的分离。N-月桂酰肌氨酸钠盐用作消泡补充剂或细菌或其他细胞裂解缓冲液的成分。这表明胶束中间相的顺磁各向异性符号发生了变化。N-月桂酰肌氨酸钠盐对己糖激酶和人类唾液/肠道菌群的抑制率为 0.25%。它在水分散体(1%)中也表现出杀菌活性。N-月桂酰肌氨酸(LS)是一种具有蛋白质变性能力的阴离子表面活性剂,结构类似于月桂酸硫酸钠(SLS)。它在体外能使单纯疱疹病毒(HSV)失去传染性。它也可用作阴道外用制剂中的杀菌剂,以阻止HSV、人类免疫缺陷病毒1型(HIV-1)和其它导致性传播疾病(STD)的病原体的传播。 The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs) |
| 纯度 | ≥99%(HPLC) |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 205-281-5 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | sodium;2-[dodecanoyl(methyl)amino]acetate |
| INCHI | 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1 |
| InChi Key | KSAVQLQVUXSOCR-UHFFFAOYSA-M |
| Smiles | CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+] |
| Isomeric SMILES | CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+] |
| 分子量 | 293.39 |
| Beilstein号 | 5322974 |
| Reaxy-Rn | 5322974 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5322974&ln= |
| 溶解性 | H2O:1M at20°C,透明,无色 |
|---|---|
| 敏感性 | 对湿度敏感 |
| 闪点(℉) | 512.6 °F |
| 闪点(℃) | 267 °C |
| 熔点 | 46°C(lit.) |
| 分子量 | 293.380 g/mol |
| XLogP3 | |
| 氢键供体数Hydrogen Bond Donor Count | 0 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 12 |
| 精确质量Exact Mass | 293.197 Da |
| 单同位素质量Monoisotopic Mass | 293.197 Da |
| 拓扑极表面积Topological Polar Surface Area | 60.400 Ų |
| 重原子数Heavy Atom Count | 20 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 260.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 2 |
| 象形图 | GHS05, GHS06, GHS07 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H315: 引起皮肤刺激 H318: 造成严重的眼睛损伤 H319: 引起严重眼睛刺激 H330: 吸入致命 |
| 预防措施声明 |
P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P284: 如果通风不良,请佩戴呼吸防护装置。 P320: 迫切需要特殊治疗(请参阅此标签上的...)。 P321: 特殊处理(请参阅此标签上的...)。 P302+P352: 如皮肤沾染:用水充分清洗。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛:立即用水冲洗几分钟。取下隐形眼镜(如果有的话),并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。 P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。 P316: 立即寻求紧急医疗救助。 |
| WGK Germany | 1 |
| RTECS | MC0598960 |
| Merck Index | 4368 |
| 个人防护装备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
¥169.90
¥1,047.90
¥443.90
¥259.90
¥29.90
| 1. Julien Couthouis,Karine Rébora,Françoise Immel,Karine Berthelot,Michel Castroviejo,Christophe Cullin. (2009-03-06) Screening for toxic amyloid in yeast exemplifies the role of alternative pathway responsible for cytotoxicity.. PloS one, 4 ((3)): (e4539-e4539). [PMID:19262694] |
| 2. Gültekin Tamgüney,Kevin P Francis,Kurt Giles,Azucena Lemus,Stephen J DeArmond,Stanley B Prusiner. (2009-08-27) Measuring prions by bioluminescence imaging.. Proceedings of the National Academy of Sciences of the United States of America, 106 ((35)): (15002-15006). [PMID:19706444] |
| 3. Linda A Terry,Laurence Howells,Keith Bishop,Claire A Baker,Sally Everest,Leigh Thorne,Ben C Maddison,Kevin C Gough. (2011-05-20) Detection of prions in the faeces of sheep naturally infected with classical scrapie.. Veterinary research, 42 (65-65). [PMID:21592355] |
| 4. Ana Beatriz Costa Rodrigues Alves,Rafaella Souza dos Santos,Susana de Santana Calil,Rivaldo Niero,Jhonny da Silva Lopes,Fábio F Perazzo,Paulo César Pires Rosa,Sérgio Faloni Andrade,Valdir Cechinel-Filho,Edson Luis Maistro. (2014-04-02) Genotoxic assessment of Rubus imperialis (Rosaceae) extract in vivo and its potential chemoprevention against cyclophosphamide-induced DNA damage.. Journal of ethnopharmacology, 153 ((3)): (694-700). [PMID:24685582] |
| 5. Nicholas J Bradshaw,Verian Bader,Ingrid Prikulis,Angelika Lueking,Stefan Müllner,Carsten Korth. (2014-10-22) Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia.. PloS one, 9 ((10)): (e111196-e111196). [PMID:25333879] |
| 6. William F Penwell,Adam B Shapiro,Robert A Giacobbe,Rong-Fang Gu,Ning Gao,Jason Thresher,Robert E McLaughlin,Michael D Huband,Boudewijn L M DeJonge,David E Ehmann,Alita A Miller. (2015-01-07) Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii.. Antimicrobial agents and chemotherapy, 59 ((3)): (1680-1689). [PMID:25561334] |
| 7. Noriyuki Doukyu,Shyou Nihei. (2015-01-13) Cholesterol oxidase with high catalytic activity from Pseudomonas aeruginosa: Screening, molecular genetic analysis, expression and characterization.. Journal of bioscience and bioengineering, 120 ((1)): (24-30). [PMID:25573142] |
| 8. Ana Vulić, Ksenija Durgo, Jelka Pleadin, Luka Herceg, Nevenka Kopjar,. (2015-01-18) Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, ( 82-92 ). [PMID:25595371] |
| 9. Flora Tolentino,Priscila Alves de Araújo,Eduardo de Souza Marques,Marcel Petreanu,Sérgio Faloni de Andrade,Rivaldo Niero,Fábio F Perazzo,Paulo César Pires Rosa,Edson Luis Maistro. (2015-02-15) In vivo evaluation of the genetic toxicity of Rubus niveus Thunb. (Rosaceae) extract and initial screening of its potential chemoprevention against doxorubicin-induced DNA damage.. Journal of ethnopharmacology, 164 (89-95). [PMID:25681544] |
| 10. Alexandra Steffens,Andrea Bräutigam,Marc Jakoby,Martin Hülskamp. (2015-07-03) The BEACH Domain Protein SPIRRIG Is Essential for Arabidopsis Salt Stress Tolerance and Functions as a Regulator of Transcript Stabilization and Localization.. PLoS biology, 13 ((7)): (e1002188-e1002188). [PMID:26133670] |
| 11. Pamela J Skinner,Hyeon O Kim,Damani Bryant,Nikilyn J Kinzel,Cavan Reilly,Suzette A Priola,Anne E Ward,Patricia A Goodman,Katherine Olson,Davis M Seelig. (2015-07-03) Treatment of Prion Disease with Heterologous Prion Proteins.. PloS one, 10 ((7)): (e0131993-e0131993). [PMID:26134409] |
| 12. Teresa L Mastracci,Morgan A Robertson,Raghavendra G Mirmira,Ryan M Anderson. (2015-08-25) Polyamine biosynthesis is critical for growth and differentiation of the pancreas.. Scientific reports, 5 (13269-13269). [PMID:26299433] |
| 13. Laurel D Wright,Christopher M Johnson,Alan D Grossman. (2015-10-07) Identification of a Single Strand Origin of Replication in the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis.. PLoS genetics, 11 ((10)): (e1005556-e1005556). [PMID:26440206] |
| 14. J J Padilla-Frausto,L G Cepeda-Marquez,L M Salgado,M H Iturriaga,S M Arvizu-Medrano. (2015-11-29) Detection and Genotyping of Leuconostoc spp. in a Sausage Processing Plant.. Journal of food protection, 78 ((12)): (2170-2176). [PMID:26613911] |
| 15. Carl Alexander Sandhof,Simon Oliver Hoppe,Silke Druffel-Augustin,Christian Gallrein,Janine Kirstein,Cindy Voisine,Carmen Nussbaum-Krammer. (2019-07-30) Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading.. Autophagy, 16 ((5)): (878-899). [PMID:31354022] |
| 16. Iryna Benilova,Madeleine Reilly,Cassandra Terry,Adam Wenborn,Christian Schmidt,Aline T Marinho,Emmanuel Risse,Huda Al-Doujaily,Michael Wiggins De Oliveira,Malin K Sandberg,Jonathan D F Wadsworth,Parmjit S Jat,John Collinge. (2020-09-10) Highly infectious prions are not directly neurotoxic.. Proceedings of the National Academy of Sciences of the United States of America, 117 ((38)): (23815-23822). [PMID:32900920] |
| 17. Shunfei Yan,Jiachen Xuan,Natalie Brajanovski,Madeleine R C Tancock,Piyush B Madhamshettiwar,Kaylene J Simpson,Sarah Ellis,Jian Kang,Carleen Cullinane,Karen E Sheppard,Katherine M Hannan,Ross D Hannan,Elaine Sanij,Richard B Pearson,Keefe T Chan. (2020-11-12) The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.. British journal of cancer, 124 ((3)): (616-627). [PMID:33173151] |
| 18. Yuying Zhang, Ying Wang, Xuhui Huang, Jie Zheng, Libo Qi, Baoshang Fu, Lei Qin. (2023) Nutritional value of different parts from sea eel (Astroconger myriaster) determined by untargeted-lipidomic approach. FOOD RESEARCH INTERNATIONAL, 173 (113402). [PMID:37803738] [10.1016/j.foodres.2023.113402] |
| 19. Siwenjie Qian, Yanju Chen, Cheng Peng, Xiaofu Wang, Hui Wu, Yang Che, Huanying Wang, Junfeng Xu, Jian Wu. (2022) Dipstick-based rapid nucleic acids purification and CRISPR/Cas12a-mediated isothermal amplification for visual detection of African swine fever virus. TALANTA, 242 (123294). [PMID:35149424] [10.1016/j.talanta.2022.123294] |
| 20. Mengle Huang, Yanjun Tang, Peng Zhu. (2021) Effect of sodium N-lauroylsarcosinate/hypromellose on the dispersibility and rheological behavior of carbon black for paper coating application. PROGRESS IN ORGANIC COATINGS, 160 (106514). [10.1016/j.porgcoat.2021.106514] |
| 21. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785] [10.1088/1748-605X/ac0088] |
| 22. Yu-Ying Zhang, Yu-Xi Liu, Zheng Zhou, Da-Yong Zhou, Ming Du, Bei-Wei Zhu, Lei Qin. (2019) Improving Lipidomic Coverage Using UPLC-ESI-Q-TOF-MS for Marine Shellfish by Optimizing the Mobile Phase and Resuspension Solvents. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (31): (8677–8688). [PMID:31293164] [10.1021/acs.jafc.9b01343] |
| 23. Shaoxin Deng, Chengxiang Shi, Xueyan Xu, Hui Zhao, Pingchuan Sun, Tiehong Chen. (2014) Synergy between Polyamine and Anionic Surfactant: A Bioinspired Approach for Ordered Mesoporous Silica. LANGMUIR, 30 (9): (2329–2334). [PMID:24571136] [10.1021/la404478b] |