| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| N475315-10mg |
10mg |
期货  |
|
| 英文别名 | NSC-350593 | MLS002207097 | F30153 | fMLP; N-Formyl-MLF | N-Formyl-MLF | HY-P0224 | (S)-2-((S)-2-((S)-2-Formamido-4-(methylthio)butanamido)-4-methylpentanamido)-3-phenylpropanoicacid | (E)-methyl 4-hydroxycinnamate | fMLF | fMLP;N-Formyl-MLF | L-Phenylala |
|---|---|
| 规格或纯度 | UltraBio™, 超纯级, ≥99%(TLC) |
| 英文名称 | N-Formyl-Met-Leu-Phe |
| 生化机理 | N-甲酰基-Met-Leu-Phe是一种有效的趋化肽和甲酰肽受体（FPR）激动剂，可诱导巨噬细胞的代谢爆发，伴随呼吸四氯、溶酶体酶分泌和超氧阴离子产生的增加。有效的趋化肽。诱导巨噬细胞的代谢爆发，并伴随着呼吸速率的增加、溶酶体酶的分泌以及超氧阴离子的产生。 |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 作用类型 | 激动剂 |
| 作用机制 | FPR1 激动剂;FPR2/ALX 激动剂 |
| 纯度 | ≥99%(TLC) |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | (2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid |
| INCHI | 1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1 |
| InChi Key | PRQROPMIIGLWRP-BZSNNMDCSA-N |
| Smiles | CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CCSC)NC=O |
| Isomeric SMILES | CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCSC)NC=O |
| 关联CAS | 59880-97-6 |
| MeSH Entry Terms | F Met Leu Phe;F-Met-Leu-Phe;fMet Leu Phe;fMet-Leu-Phe;Formylmet Leu Phe;Formylmet-Leu-Phe;Formylmethionyl Leucyl Phenylalanine;Formylmethionyl Peptide;Formylmethionyl-Leucyl-Phenylalanine;Formylmethionylleucylphenylalanine;Leucyl-Phenylalanine, N-Formylme |
| 分子量 | 437.55 |
| Beilstein号 | 2315783 |
| Reaxy-Rn | 8397445 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8397445&ln= |
| 溶解性 | DMF：50mg/mL，透明，无色 |
|---|---|
| 比旋光度 | -8° (C=1,AcOH) |
| 熔点 | 213 °C |
| 分子量 | 437.600 g/mol |
| XLogP3 | 1.500 |
| 氢键供体数Hydrogen Bond Donor Count | 4 |
| 氢键受体数Hydrogen Bond Acceptor Count | 6 |
| 可旋转键计数Rotatable Bond Count | 13 |
| 精确质量Exact Mass | 437.198 Da |
| 单同位素质量Monoisotopic Mass | 437.198 Da |
| 拓扑极表面积Topological Polar Surface Area | 150.000 Ų |
| 重原子数Heavy Atom Count | 30 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 567.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 3 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| WGK Germany | 3 |
|---|---|
| 个人防护装备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
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