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诺考达唑

微管抑制剂
15篇引用文献 COA COA
    级别和纯度:
  • ≥98%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
N129755-10mg
 10mg 现货 Stock Image
N129755-50mg
 50mg 现货 Stock Image
N129755-250mg
 250mg 现货 Stock Image
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查看相关系列
Apoptosis (7108) Autophagy (2848) Bcr-Abl (60) Cell Cycle (7376) Cell Cycle/DNA Damage (2603) CRISPR/Cas9 (10) Cytoskeleton (497) DNA Damage (3514) Microtubule/Tubulin (197) Non-receptor Tyrosine Kinase (1390) Protein Tyrosine Kinase/RTK (1319) 药物成分 (367)
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基本描述

别名 [5-(2-噻吩羰基)-1H-苯并咪唑-2-基]氨基甲酸甲酯 | 甲基N(5-噻吩甲酰-2-苯并咪唑基)氨基甲酸 | 甲基-(5-噻吩甲酰-2-苯并咪唑基)氨基甲酸
英文别名 HMS587E01 | Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate | MLS001164242 | DTXCID7011800 | KBio3_002735 | Prestwick2_000100 | Tocris-1228 | Bio1_000950 | cid_4122 | Methyl(5-(2-thienylcarbonyl))-1H-benzimidazole-2-yl carbamate | Nocodazol
规格或纯度 ≥98%
英文名称 Nocodazole
生化机理 Nocodazole是一种微管聚合的快速可逆抑制剂，也抑制Abl， Abl(E255K)和Abl(T315I)，IC50分别为0.21 μM， 0.53 μM和0.64 μM。微管抑制剂。在体内快速解聚微管，在体外抑制微管蛋白聚合。抑制有丝分裂。还降低了干细胞多能性因子Oct 4和Nanog。
应用 A potent Tubulin production inhibitor and anti-neoplastic agent
储存温度 -20°C储存
运输条件 超低温冰袋运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

Nocodazole is a reversible anti-neoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules (tubulin). Several drμgs including vincristine and colcemid are similar to nocodazole in that they interfere with microtubule polymerization. Nocodazole is frequently employed in cell biology laboratories to synchronize the cell division cycle; cells treated with nocodazole arrest with a G2- or M-phase DNA content when analyzed by flow cytometry. Nocodazole has also been used to induce the formation of Golgi ministacks in eukaryotic cells due to lack of proper Tubulin function.A potent Tubulin production inhibitor and anti-neoplastic agent

Nocodazole is a reversible anti-neoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules (tubulin). Several drugs including vincristine and colcemid are similar to nocodazole in that they interfere with microtubule polymerization. Nocodazole is frequently employed in cell biology laboratories to synchronize the cell division cycle; cells treated with nocodazole arrest with a G2- or M-phase DNA content when analyzed by flow cytometry. Nocodazole has also been used to induce the formation of Golgi ministacks in eukaryotic cells due to lack of proper Tubulin function.
A potent Tubulin production inhibitor and anti-neoplastic agent
纯度 ≥98%

关联靶点（人）

CYP1A2 Tchem 细胞色素 P450 1A2(Cytochrome P450 1A2) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ABL1 Tclin Tyrosine-protein kinase ABL (18331 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
INSR Tclin Insulin receptor (5558 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Sigmar1 Sigma opioid receptor (160 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cckar Cholecystokinin A receptor (90 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TUBB2B Tubulin beta chain (424 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TUBA1A Tubulin alpha chain (497 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Saccharomyces cerevisiae (19171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Trypanosoma brucei (78846 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
B16 (5829 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L1210 (27553 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P388/ADR (1216 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Vero (26788 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NIH3T3 (5395 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
LT12 tumor cell line (10 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
4T1 (1737 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
B16-F10 (4610 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Npsr1 Neuropeptide S receptor (260 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Danio rerio (3092 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Paracentrotus lividus (1138 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Giardia (1682 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TUBB2B Tubulin (2175 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Glra2 Glycine receptor (1745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504750751
EC号 250-626-5
分子类型 小分子
IIUPAC Name methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
INCHI 1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
InChi Key KYRVNWMVYQXFEU-UHFFFAOYSA-N
Smiles COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
Isomeric SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
UN Number 2811
Packing Group I
分子量 301.32
Beilstein号 1085978
Reaxy-Rn 1018009
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1018009&ln=

化学和物理性质

溶解性 Soluble in DMSO (10 mg/ml);Soluble in Ethanol (1 mg/ml)
敏感性 对热敏感
熔点 260 °C
分子量 301.320 g/mol
XLogP3 2.800
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 4
精确质量Exact Mass 301.052 Da
单同位素质量Monoisotopic Mass 301.052 Da
拓扑极表面积Topological Polar Surface Area 112.000 Ų
重原子数Heavy Atom Count 21
形式电荷Formal Charge 0
复杂度Complexity 420.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS08
信号词 警告
危险声明

H341: 怀疑引起遗传缺陷

H361: 怀疑破坏生育力或未出生的孩子
预防措施声明

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P281: 根据需要使用个人防护设备。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P203: 使用前，获取、阅读并遵守所有安全说明。

P318: 如果暴露或担心，请就医。
WGK Germany 3
RTECS DD6521000
Class 6.1
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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A2206883 分析证书 N129755
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G2516569 分析证书 N129755
G2516570 分析证书 N129755
H2304186 分析证书 N129755
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引用文献

1. Lee BY & Hur EM.  (2020)  A Role of Microtubules in Oligodendrocyte Differentiation..  Int J Mol Sci,  21  (3): [PMID:32033476]
2. Tabdanov ED et al..  (2018)  Bimodal sensing of guidance cues in mechanically distinct microenvironments..  Nat Commun,  9  (4891).  [PMID:30459308]
3. Yan H et al..  (2022)  CDK5RAP3, an essential regulator of checkpoint, interacts with RPL26 and maintains the stability of cell growth..  Cell Prolif,  55  (5): (e13240).  [PMID:35509151]
4. Salemi LM et al..  (2015)  Characterization of RanBPM molecular determinants that control its subcellular localization..  PLoS One,  10  (2): (e0117655).  [PMID:25659156]
5. Ocampo J et al..  (2019)  Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination..  Genome Res,  29  (3): (407-417).  [PMID:30683752]
6. Endo Y et al..  (2022)  Genome‑wide DNA hypomethylation drives a more invasive pancreatic cancer phenotype and has predictive occult distant metastasis and prognosis potential..  Int J Oncol,  60  (6): [PMID:35419613]
7. Ramos D et al..  (2016)  Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells..  PLoS One,  11  (3): (e0149516).  [PMID:26934375]
8. Musa H et al..  (2003)  Microtubule assembly in cultured myoblasts and myotubes following nocodazole induced microtubule depolymerisation..  J Muscle Res Cell Motil,  24  (4-6): (301-8).  [PMID:14620743]
9. Tabdanov ED et al..  (2018)  Microtubule-Actomyosin Mechanical Cooperation during Contact Guidance Sensing..  Cell Rep,  25  (2): (328-338.e5).  [PMID:30304674]
10. Vasquez RJ et al..  (1997)  Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro..  Mol Biol Cell,  8  (6): (973-85).  [PMID:9201709]
11. Kallas A et al..  (2011)  Nocodazole treatment decreases expression of pluripotency markers Nanog and Oct4 in human embryonic stem cells..  PLoS One,  6  (4): (e19114).  [PMID:21559451]
12. Wu B et al..  (2020)  Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells..  Cell Metab,  32  (6): (967-980.e5).  [PMID:33264602]
13. Sugita S et al..  (2019)  Tumor-suppressive microRNA-223 targets WDR62 directly in bladder cancer..  Int J Oncol,  54  (6): (2222-2236).  [PMID:30942440]
14. Wufa Fan,§ Jiajia Xiang,§ Qiuyu Wei,§ Yisi Tang,§ Ying Piao, Shiqun Shao, Zhuxian Zhou,* Jianbin Tang, Zi-Chen Li,* and Youqing Shen*.  (2023)  Role of Micelle Size in Cell Transcytosis-Based Tumor Extravasation, Infiltration, and Treatment Efficacy.  Nano letters,  9  (23): (3904-3912).  [PMID:37043295] [10.1021/acs.nanolett.3c00449]
15. Yuan-Yuan Liu, Jie Liu, Hao Wu, Qiangqiang Zhang, Xue-Rui Tang, Dan Li, Chen-Si Li, Yuanfang Liu, Aoneng Cao, Haifang Wang.  (2023)  Endocytosis, Distribution, and Exocytosis of Polystyrene Nanoparticles in Human Lung Cells.  Nanomaterials,  13  (1): (84).  [PMID:36615994] [10.3390/nano13010084]
16. Junzhao Yuan, Xiaoqian Huang, Yumeng Zhao, Jianhong Gu, Yan Yuan, Zongping Liu, Hui Zou, Jianchun Bian.  (2022)  Rat Hepatocytes Mitigate Cadmium Toxicity by Forming Annular Gap Junctions and Degrading Them via Endosome–Lysosome Pathway.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  23  (24): (15607).  [PMID:36555247] [10.3390/ijms232415607]
17. Siqin Chen, Quan Zhou, Guowei Wang, Zhuxian Zhou, Jianbin Tang, Tao Xie, Youqing Shen.  (2021)  Effect of Cationic Charge Density on Transcytosis of Polyethylenimine.  BIOMACROMOLECULES,  22  (12): (5139–5150).  [PMID:34775750] [10.1021/acs.biomac.1c01109]
18. Wenjie Feng, Wanrui Shi, Shuwei Liu, Huiwen Liu, Yi Liu, Pengfei Ge, Hao Zhang.  (2021)  Fe(III)-Shikonin Supramolecular Nanomedicine for Combined Therapy of Tumor via Ferroptosis and Necroptosis.  Advanced Healthcare Materials,  11  (2): (2101926).  [PMID:34738742] [10.1002/adhm.202101926]
19. Chen Xiaolong, Hu Cuihua, Zhang Yanan, Hao Wenjing, He Xu, Li Qing, Huang Yuxi, Huang Yibing, Chen Yuxin.  (2020)  Anticancer Activity and Mechanism of Action of kla-TAT Peptide.  International Journal of Peptide Research and Therapeutics,  26  (4): (2285-2296).  [10.1007/s10989-020-10019-5]
20. Peng Zhang, Bangbang Li, Jianwei Du, Youxiang Wang.  (2017)  Regulation the morphology of cationized gold nanoparticles for effective gene delivery.  COLLOIDS AND SURFACES B-BIOINTERFACES,  157  (18).  [PMID:28558339] [10.1016/j.colsurfb.2017.04.056]
21. Mengxin Zhang, Yingyu Zhang, Qionglin Wang, Kangbo Liu, Lifeng Li, Zhidan Yu, Ligong Hou, Xianwei Zhang, Huan Zhao, Weyland Cheng, Wancun Zhang.  (2024)  An APE1 gated signal amplified biosensor driven by catalytic hairpin assembly for the specific imaging of microRNA in situ.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  262  (129902).  [PMID:38307426] [10.1016/j.ijbiomac.2024.129902]
22. Mengxin Zhang, Yingyu Zhang, Xianwei Zhang, Kangbo Liu, Lifeng Li, Zhidan Yu, Jingya Yuan, Wancun Zhang.  (2024)  An Enzymatically Activated and Catalytic Hairpin Assembly-Driven Intelligent AND-Gated DNA Network for Tumor Molecular Imaging.  ANALYTICAL CHEMISTRY,  96  (24): (10084-10091).  [PMID:38836421] [10.1021/acs.analchem.4c02076]
23. Mengxin Zhang, Yingyu Zhang, Xianwei Zhang, Qionglin Wang, Kangbo Liu, Muchun Yu, Lifeng Li, Zhidan Yu, Huan Zhao, Weyland Cheng, Wancun Zhang.  (2024)  An enzymatically activated self-powered and self-recycled strategy for in situ tumor cell-specific molecular imaging.  CHEMICAL ENGINEERING JOURNAL,  489  (151226).  [10.1016/j.cej.2024.151226]
24. Dan Li, Gaoyang Yi, Guifang Cao, Adam C. Midgley, Yongli Yang, Dan Yang, Wenguang Liu, Yujuan He, Xiaolin Yao, Guoliang Li.  (2025)  Dual-Carriers of Tartary Buckwheat-Derived Exosome-Like Nanovesicles Synergistically Regulate Glucose Metabolism in the Intestine-Liver Axis.  Small,  (2410124).  [PMID:40079102] [10.1002/smll.202410124]
25. Xingkang Diao, GuoHua Qi, Xinli Li, Yu Tian, Jing Li, Yongdong Jin.  (2025)  Label-Free Exosomal SERS Detection Assisted by Machine Learning for Accurately Discriminating Cell Cycle Stages and Revealing the Molecular Mechanisms during the Mitotic Process.  ANALYTICAL CHEMISTRY,  [PMID:39999424] [10.1021/acs.analchem.4c06240]
26. Yue Wang, Ping Wang, Haiyan Li, Xiaoran Han, Haibin Zhu, Xiangqun Jin.  (2024)  Nanocrystal-Loaded Lipid Carriers for Improved Oral Absorption and Anticancer Efficacy of Etoposide: Formulation Development, Transport Mechanism, In Vitro and In Vivo Evaluation.  MOLECULAR PHARMACEUTICS,  21  (3): (1170-1181).  [PMID:38329909] [10.1021/acs.molpharmaceut.3c00785]
27. Yang Chen, Wenzhe Xu, Hao Jin, Mengsi Zhang, Shuwei Liu, Yi Liu, Hao Zhang.  (2024)  Nutritional Glutamine-Modified Iron-Delivery System with Enhanced Endocytosis for Ferroptosis Therapy of Pancreatic Tumors.  ACS Nano,  18  (46): (31846-31868).  [PMID:39512234] [10.1021/acsnano.4c08083]
28. Dan Yang, Yuqi Feng, Ying Yuan, Linxuan Zhang, Yao Zhou, Adam C. Midgley, Yanrong Wang, Ning Liu, Guoliang Li, Xiaolin Yao, Dechun Liu.  (2024)  Protein Coronas Derived from Mucus Act as Both Spear and Shield to Regulate Transferrin Functionalized Nanoparticle Transcellular Transport in Enterocytes.  ACS Nano,  [PMID:38417159] [10.1021/acsnano.3c11315]
29. Huan Tang, Jie Zhou, Tong Yang, Hai-Ning Lyu, Zheng Chu, Ying Zhang, Ang Ma, Junzhe Zhang, Yuqing Meng, Chong Qiu, Sheng-Tao Yang, Jigang Wang, Zipeng Gong.  (2025)  Understanding the biological identity of metal-organic framework through profiling proteomic fingerprinting of protein corona.  CHEMICAL ENGINEERING JOURNAL,  509  (161320).  [10.1016/j.cej.2025.161320]

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