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尼罗红

耐光，亲脂性污渍
385篇引用文献 COA COA
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货号 (SKU) 包装规格 是否现货 价格 数量
N121291-250mg
 250mg 现货 Stock Image
N121291-1g
 1g 现货 Stock Image
N121291-5g
 5g 现货 Stock Image
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Fluorescent Dye (370) 六元杂环化合物 (1701) 荧光指示剂和探针 (13)
main product photo

基本描述

别名 9-(二乙胺基)-5H-苯并[a]吩恶嗪-5-酮
英文别名 9-(diethylamino)-5H-benzo[a]phenoxazin-5-one | 9-(diethylamino)benzo[a]phenoxazin-5-one | Nile Blue A Oxazone | 9-(Diethylamino)-5H-benzo(a)pheno
规格或纯度 BioReagent, 适用于荧光分析, ≥95%(HPLC)
英文名称 Nile Red
生化机理 光稳定的亲脂性\ xa0染色剂在疏水性（富含脂质）环境中强烈发出荧光，但在水性介质中的荧光却很少。
应用 A photostable, lipophilic stain with bright red fluorescence
储存温度 避光,室温,充氩
运输条件 常规运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

尼罗河红为不带电荷的疏水分子，是苯并吩恶嗪酮染料。它用作细胞内脂质和蛋白疏水结构域的荧光探针。这种染料在所有有机溶剂中均发出荧光。其荧光颜色范围从金黄色到深红色。
产品用途：

尼罗红用于细胞内脂滴和中性脂质的染色。

Nile Red is an uncharged, hydrophobic, photostable molecule that strongly fluoresces bright red in hydrophobic environments. This lipophilic stain is commonly used for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytofluorometry. Nile Red has been shown to detect the exposure or formation of new hydrophobic surfaces induced by ligand binding to calmodulin, oligomerization of melittin, or unfolding of ovalbumin during early thermal denaturation. This product has been employed to stain cell structures, as well as to visualize and localize colloidal drug carriers. Nile Red's fluorescence is unaffected between pH 4.5 and 8.5 and may be used in dilute concentrations to investigate hydrophobic protein sites.
A photostable, lipophilic stain with bright red fluorescence
纯度 ≥95%(HPLC)

关联靶点（人）

VDR Tclin Vitamin D receptor (26531 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLB Tchem DNA polymerase beta (23632 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLI Tchem DNA polymerase iota (116820 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GPR55 Tclin G-protein coupled receptor 55 (1594 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NPC1 Tchem Niemann-Pick C1 protein (18985 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAB9A Tbio Ras-related protein Rab-9A (22488 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
microRNA 21 (64692 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APOBEC3F Tbio DNA dC->dU-editing enzyme APOBEC-3F (14861 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium berghei (192651 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cavia porcellus (23802 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L6 (7924 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Luciferin 4-monooxygenase (66902 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504753968
EC号 230-966-0
分子类型 小分子
IIUPAC Name 9-(diethylamino)benzo[a]phenoxazin-5-one
INCHI 1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
InChi Key VOFUROIFQGPCGE-UHFFFAOYSA-N
Smiles CCN(CC)C1=CC2=C(C=C1)N=C3C4=CC=CC=C4C(=O)C=C3O2
Isomeric SMILES CCN(CC)C1=CC2=C(C=C1)N=C3C4=CC=CC=C4C(=O)C=C3O2
分子量 318.37
Beilstein号 279110
Reaxy-Rn 279110
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=279110&ln=

化学和物理性质

溶解性 Soluble in water (Partly miscible), and methanol (1 mg/ml).
敏感性 对光线和空气敏感
熔点 203-205°C
分子量 318.400 g/mol
XLogP3 3.800
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 318.137 Da
单同位素质量Monoisotopic Mass 318.137 Da
拓扑极表面积Topological Polar Surface Area 41.900 Ų
重原子数Heavy Atom Count 24
形式电荷Formal Charge 0
复杂度Complexity 564.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

WGK Germany 3
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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批号(Lot Number) 证书类型 货号
G2524429 分析证书 N121291
G2524430 分析证书 N121291
G2524433 分析证书 N121291
C2512536 分析证书 N121291
C2512568 分析证书 N121291
F2513109 分析证书 N121291
G2511074 分析证书 N121291
C2512537 分析证书 N121291
J2424803 分析证书 N121291
J2424724 分析证书 N121291
G2408316 分析证书 N121291
G2408311 分析证书 N121291
D2418492 分析证书 N121291
D2418493 分析证书 N121291
D2418277 分析证书 N121291
D2418488 分析证书 N121291
L2315296 分析证书 N121291
L2315298 分析证书 N121291
L2315295 分析证书 N121291
B2302578 分析证书 N121291
B2302579 分析证书 N121291
B2302580 分析证书 N121291
A2219025 分析证书 N121291
A2219023 分析证书 N121291
A2219024 分析证书 N121291

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引用文献

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355. Hengheng Wang, Geoffrey I.N. Waterhouse, Huan Xiang, Dongxiao Sun-Waterhouse, Yongqiang Zhao, Shengjun Chen, Yanyan Wu, Yueqi Wang.  (2024)  Mechanisms of slow-release antibacterial properties in chitosan‑titanium dioxide stabilized perilla essential oil Pickering emulsions: Focusing on oil-water interfacial behaviors.  CARBOHYDRATE POLYMERS,  346  (122613).  [PMID:39245524] [10.1016/j.carbpol.2024.122613]
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369. Huilan Zhang, Qinbo Jiang, Jiawen Li, Yifeng Sun, Ruihao Zhang, Liang Zhang, Hui Zhang.  (2024)  Oil-droplet anchors accelerate the gelation of regenerated silk fibroin-based emulsion gels.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  (134579).  [PMID:39122082] [10.1016/j.ijbiomac.2024.134579]
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372. Sunqi Yu, Siyuan Chen, Tianrui Tong, Yunfeng Yan, Qi Shuai.  (2025)  pH and ROS Dual-Responsive Core-Cross-Linked Micelles Based on Boronic Ester Linkage for Efficient PTX Delivery.  JOURNAL OF POLYMER SCIENCE,  [10.1002/pol.20241133]
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374. Xue Zhang, Jinchang Liu, Jialin Jia, Hao Xing, Junkang Yang, Tao He, Huajie Liu, Tao Zhang, Wenna Wu.  (2025)  pH-responsive antibacterial emulsion gel based on cinnamaldehyde and carboxymethyl chitosan for fruits preservation applications.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  291  (139062).  [PMID:39710029] [10.1016/j.ijbiomac.2024.139062]
375. Yejun Zhong, Shan Sun, Taotao Dai, Hui Zhang, Jianyong Wu, Er Sheng Gong.  (2024)  Phycocyanin-chitosan complex stabilized emulsion: Preparation, characteristics, digestibility, and stability.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  260  (129253).  [PMID:38218297] [10.1016/j.ijbiomac.2024.129253]
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377. Yong-Hui Wang, Sheng-Hua He, Ji-Hong Huang, Wei-Yun Guo, Xue-Li Gao, Guang-Hui Li.  (2024)  Physicochemical stability of corn protein hydrolysate/tannic acid complex-based β-carotene nanoemulsion delivery system.  Food Science & Nutrition,  [PMID:39055182] [10.1002/fsn3.4160]
378. Ting-Bin Hao, Peng-Yu Lai, Zhan Shu, Ran Liang, Zhi-Yun Chen, Ren-Long Huang, Yang Lu, Adili Alimujiang.  (2025)  Physiological and metabolic fluctuations of the diatom Phaeodactylum tricornutum under water scarcity.  Frontiers in Microbiology,  16  [PMID:40177482] [10.3389/fmicb.2025.1555989]
379. Yitong Wang, Hui Teng, Shuxian Bai, Chen Li, Ye Wang, Linyin Ma, Yanjun Zhang, Lei Chen.  (2024)  Pickering emulsion of camellia oil stabilized by Octenyl succinic acid starch: Interaction, lipid oxidation and digestibility.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  279  (135108).  [PMID:39244123] [10.1016/j.ijbiomac.2024.135108]
380. Ying Liu, Liang Liu, Xinxia Li, Juan Yu, Meijuan Chen, Lin Lin, Ruoxian Jia, Yimin Fan.  (2024)  Pickering emulsions by combining nanocellulose/nanochitin and silk fibroin: Silk fibroin as a stabilizer or an emulsifier.  INDUSTRIAL CROPS AND PRODUCTS,  211  (118270).  [10.1016/j.indcrop.2024.118270]
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387. Beiduo Wang, Yanping Xu, Qigu Yao, Liang Song, Min Liang, Hongcui Cao, Changyou Gao.  (2024)  Prolonged resident nanoparticles effectively treat acute lung injury via the selective upregulation of intracellular hydrogen peroxide.  Nano Today,  56  (102278).  [10.1016/j.nantod.2024.102278]
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