基本描述

别名	硫化剂MOCA
英文别名	3,4'-diaminodifenilmetano \| Methylenebis(3-chloro-4-aminobenzene) \| methylenebis(o-chloroaniline) \| 3L2W5VTT2A \| 4,4'-Methylene(bis)-chloroaniline \| Benzenamine, ar,ar'-methylenebis(2-chloro- \| HMS3039N14 \| 4,4-Metilene-bis-o-cloroanilina [Italian] \| 4,4'
规格或纯度	≥85%
英文名称	4,4′-Methylene-bis(2-chloroaniline)
运输条件	常规运输
产品介绍	熔融物比重1.213(107/4℃).溶于稀酸、醚和醇，微溶于水，水溶性<0.1g/100ml at 25℃微有吸收性
纯度	≥85%

关联靶点（人）

ESR1 Tclin Estrogen receptor alpha (17718 活性数据)

点击查看靶蛋白信息： ESR1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)

点击查看靶蛋白信息： NR3C1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 活性数据)

点击查看靶蛋白信息： PPARG

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 活性数据)

点击查看靶蛋白信息： KCNH2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 活性数据)

点击查看靶蛋白信息： RXRA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CXCL8 Tchem Interleukin-8 (642 活性数据)

点击查看靶蛋白信息： CXCL8

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 活性数据)

点击查看靶蛋白信息： GLP1R

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SNCA Tchem Alpha-synuclein (10960 活性数据)

点击查看靶蛋白信息： SNCA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Rattus norvegicus (775804 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 活性数据)

点击查看靶蛋白信息： lef

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 活性数据)

点击查看靶蛋白信息： Rorc

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 活性数据)

点击查看靶蛋白信息： Nr1i2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504751387
EC号	202-918-9
分子类型	小分子
IIUPAC Name	4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline
INCHI	1S/C13H12Cl2N2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7H,5,16-17H2
InChi Key	IBOFVQJTBBUKMU-UHFFFAOYSA-N
Smiles	C1=CC(=C(C=C1CC2=CC(=C(C=C2)N)Cl)Cl)N
Isomeric SMILES	C1=CC(=C(C=C1CC2=CC(=C(C=C2)N)Cl)Cl)N
UN Number	3077
Packing Group	III
分子量	267.15
Beilstein号	1882318
Reaxy-Rn	1882318
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1882318&ln=

化学和物理性质

密度	1.4408
闪点(℃)	113°C
沸点	202-214°C
熔点	102-107°C
分子量	267.150 g/mol
XLogP3	3.800
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	2
可旋转键计数Rotatable Bond Count	2
精确质量Exact Mass	266.038 Da
单同位素质量Monoisotopic Mass	266.038 Da
拓扑极表面积Topological Polar Surface Area	52.000 Å²
重原子数Heavy Atom Count	17
形式电荷Formal Charge	0
复杂度Complexity	226.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

一般危化品	一般危化品
象形图	GHS07, GHS08, GHS09
信号词	危险
危险声明	H302: 吞食有害 H350: 可能导致癌症 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响
预防措施声明	P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P330: 漱口 P391: 收集溢出物 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。
WGK Germany	3
Class	9
Merck Index	6059

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

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找到2个结果

批号(Lot Number)	证书类型	货号
H1920127	分析证书	M299209
B2317203	分析证书	M299209

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. L Luukkanen,E Elovaara,P Lautala,J Taskinen,H Vainio. (1997-03-01) Characterization of 1-hydroxypyrene as a novel marker substrate of 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase(s).. Pharmacology & toxicology, 80 ((3)): (152-158). [PMID:9101589]
2. M Schuler,D S Rupa,D A Eastmond. (1997-08-01) A critical evaluation of centromeric labeling to distinguish micronuclei induced by chromosomal loss and breakage in vitro.. Mutation research, 392 ((1-2)): (81-95). [PMID:9269333]
3. Carmen E Perrone,Hans-Juergen Ahr,Jian Dong Duan,Alan M Jeffrey,Ulrich Schmidt,Gary M Williams,Harald H Enzmann. (2004-05-29) Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens.. Archives of toxicology, 78 ((10)): (589-598). [PMID:15167984]
4. Richard Fairfax,Edwin Porter. (2006-04-20) Evaluation of worker exposure to TDI, MOCA, and methylene chloride.. Journal of occupational and environmental hygiene, 3 ((6)): (D50-D53). [PMID:16621764]
5. J Cocker,K Jones,J Morton,H J Mason. (2007-02-27) Biomonitoring at the UK Health and Safety Laboratory.. International journal of hygiene and environmental health, 210 ((3-4)): (383-386). [PMID:17321210]
6. P Vineis,R Pirastu. (1997-05-01) Aromatic amines and cancer.. Cancer causes & control : CCC, 8 ((3)): (346-355). [PMID:9498898]
7. X G Shao,M Q Li. (2003-01-25) [Resolution of overlapping mass spectra of azobiphenyl dyes by subwindow factor analysis technique].. Se pu = Chinese journal of chromatography, 19 ((2)): (184-187). [PMID:12541672]
8. Chiu-Shong Liu,Saou-Hsing Liou,Ching-Hui Loh,Yi-Chun Yu,Shi-Nian Uang,Tung-Sheng Shih,Hong-I Chen. (2005-06-03) Occupational bladder cancer in a 4,4 -methylenebis(2-chloroaniline) (MBOCA)-exposed worker.. Environmental health perspectives, 113 ((6)): (771-774). [PMID:15929884]
9. Lijing Lu, Haoyue Ning, Jipeng Guo, Chuang Guo, Liao Pan, Lixin Lu. (2023) Synthesis, Evaluation, and Electrochemical Detection Application of Magnetic Molecularly Imprinted Polymers for 4,4-Methylenedianiline from Food-Contact Materials. ADVANCES IN POLYMER TECHNOLOGY, 2023 (9306542). [10.1155/2023/9306542]
10. Tianhong Yang, Zhaoyi He, Gang Huang, Yongli Zhao, Jianwei Fu, Hao Xiang, Yingju Zhou. (2023) Study on materials composition and process parameters of polyurethane-modified asphalt synthesized in-situ by the one-shot process. CONSTRUCTION AND BUILDING MATERIALS, 374 (130661). [10.1016/j.conbuildmat.2023.130661]
11. Wenxiu Jiao, Aimin Sha, Jin Zhang, Meng Jia, Wei Jiang, Liqun Hu. (2023) Design and properties of polyurethane solid–solid phase-change granular temperature regulation asphalt mixtures. SOLAR ENERGY, 253 (47). [10.1016/j.solener.2023.02.008]
12. Yanjie Zheng, Keli Wang, Lei Sun, Huili Shi, Xia Zhang. (2022) Preparation of PFDTS-kaolin/PU superamphiphobic coatings with antibacterial, antifouling and improved durability property. PROGRESS IN ORGANIC COATINGS, 173 (107145). [10.1016/j.porgcoat.2022.107145]
13. Yaochen Zheng, Peng Song, Shaoxiang Liu, Mengqing Wu, Hui Xu, Chenghui Qiao, Jian Liu, Zhengguo Gao, Qingfu Ban. (2021) Transparent and toughening epoxy thermosets modified by linear telechelic polymer containing rigid spiroacetal moieties: Uncovering the relationship between the heterogeneous crosslinked network and thermoset performances. JOURNAL OF POLYMER SCIENCE, 59 (13): (1390-1398). [10.1002/pol.20210178]
14. Xiongwei Wang, Peiyi Wu. (2019) 3D Vertically Aligned BNNS Network with Long-Range Continuous Channels for Achieving a Highly Thermally Conductive Composite. ACS Applied Materials & Interfaces, 11 (32): (28943–28952). [PMID:31361947] [10.1021/acsami.9b09398]
15. Ziming Shen, Jiachun Feng. (2019) Preparation of Thermally Conductive Polymer Composites with Good Electromagnetic Interference Shielding Efficiency Based on Natural Wood-Derived Carbon Scaffolds. ACS Sustainable Chemistry & Engineering, 7 (6): (6259–6266). [10.1021/acssuschemeng.8b06661]
16. Ziming Shen, Jiachun Feng. (2019) Achieving vertically aligned SiC microwires networks in a uniform cold environment for polymer composites with high through-plane thermal conductivity enhancement. COMPOSITES SCIENCE AND TECHNOLOGY, 170 (135). [10.1016/j.compscitech.2018.11.036]
17. Shusheng Chen, Bin Chen, Jiashu Fan, Jiachun Feng. (2015) Exploring the Application of Sustainable Poly(propylene carbonate) Copolymer in Toughening Epoxy Thermosets. ACS Sustainable Chemistry & Engineering, 3 (9): (2077–2083). [10.1021/acssuschemeng.5b00343]
18. Jiading Wang, Shaoyun Guo, Xianlong Zhang. (2024) Broken Chain Self-Reconnection Strategy Enables Radiation Ultraresistance of Polyurethane. MACROMOLECULES, 57 (23): (11266-11275). [10.1021/acs.macromol.4c02557]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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浓度

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体积

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分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

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体积 1 (V1)

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浓度 2 (C2)

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

=

质量（小瓶）

÷

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
M299209-50g	50g	现货
M299209-250g	250g	现货
M299209-1kg	1kg	现货

4,4'-次甲基-双(2-氯苯胺)

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器