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马波沙星

15篇引用文献 COA COA
    级别和纯度:
  • ≥98%
有货

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
M139937-1g
 1g 现货 Stock Image
M139937-5g
 5g 现货 Stock Image
M139937-25g
 25g 现货 Stock Image
M139937-100g
 100g 期货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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Antibiotic (2632) Bacterial (5911) 喹诺酮类抗生素 (16)
main product photo

基本描述

别名 9-氟代-2,3-二氢-3-甲基-10-(4-甲基-哌嗪)-7-氧代-7H-吡啶并[1,2,3-ij][1,2,4]苯并噁二嗪-6-羧酸
英文别名 BM164656 | CCG-229989 | Marbofloxacin | Marbofloxacin for peak identification, European Pharmacopoeia (EP) Reference Standard | Q-201338 | GS-3323 | Marbofloxacin, European Pharmacopoeia (EP) Reference Standard | 9-Fluoro-3-methyl-10-(4-methylpiperazin-1-
规格或纯度 ≥98%
英文名称 Marbofloxacin
应用 Fluorinated quinolone antibacterial.
运输条件 常规运输
产品介绍

Marbofloxacin is a fluorinated carboxylic acid derivative third generatino quinolone antibacterial.Fluorinated quinolone antibacterial.

Marbofloxacin is a fluorinated carboxylic acid derivative third generatino quinolone antibacterial.
Fluorinated quinolone antibacterial.
纯度 ≥98%

关联靶点（人）

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus (3973 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium yoelii yoelii (73 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus sp. 'group A' (3417 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ska Streptokinase A (5805 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504753712
分子类型 小分子
IIUPAC Name 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1,2-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
INCHI 1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
InChi Key BPFYOAJNDMUVBL-UHFFFAOYSA-N
Smiles CN1CCN(CC1)C2=C(C=C3C4=C2OCN(N4C=C(C3=O)C(=O)O)C)F
Isomeric SMILES CN1CCN(CC1)C2=C(C=C3C4=C2OCN(N4C=C(C3=O)C(=O)O)C)F
分子量 362.36
Reaxy-Rn 8397667
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8397667&ln=

化学和物理性质

密度 1.55
熔点 269°C(lit.)
分子量 362.400 g/mol
XLogP3 -0.500
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 9
可旋转键计数Rotatable Bond Count 2
精确质量Exact Mass 362.139 Da
单同位素质量Monoisotopic Mass 362.139 Da
拓扑极表面积Topological Polar Surface Area 76.600 Ų
重原子数Heavy Atom Count 26
形式电荷Formal Charge 0
复杂度Complexity 636.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

危险声明

H412: 对水生生物有害并具有长期持续影响
预防措施声明

P273: 避免释放到环境中。

P501: 将内容物/容器处理到。。。
Merck Index 5750

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到6个结果

批号(Lot Number) 证书类型 货号
C1524092 分析证书 M139937
C2202254 分析证书 M139937
C2202291 分析证书 M139937
C2202307 分析证书 M139937
C2202567 分析证书 M139937
B2512090 分析证书 M139937

此产品的引用文献

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引用文献

1. Baisen Chen, Rongxia Tan, Yanhui Zhong, Yufei Hu, Gongke Li.  (2024)  A chemiluminescence method based on Ce-PA-Tb polymer for rapid determination of difloxacin in aquatic products.  TALANTA,  267  (125217).  [PMID:37738744] [10.1016/j.talanta.2023.125217]
2. Changxing Wang, Feifei Qin, Siyuan Tang, Xiameng Li, Tingting Li, Guoqiang Guo, Chenjie Gu, Xu Wang, Da Chen.  (2023)  Construction of graphene quantum dots ratiometric fluorescent probe by intermolecular electron transfer effect for intelligent and real-time visual detection of ofloxacin and its L-isomer in daily drink.  FOOD CHEMISTRY,  411  (135514).  [PMID:36724609] [10.1016/j.foodchem.2023.135514]
3. Zhenyu Lu, Gongke Li, Yufei Hu.  (2022)  A Tb3+ functionalized triazine-porous organic framework as a ratiometric fluorescent sensor for determination of ciprofloxacin in aquatic products.  NEW JOURNAL OF CHEMISTRY,  46  (40): (19153-19160).  [10.1039/D2NJ03657F]
4. Wei Zeng, Rong Su, Wei Zhou, Xiaoqi Yu, Yuhui Zheng.  (2021)  Novel lanthanide appended hybrid hydrogel based on water-induced shape memory luminescence.  SOFT MATERIALS,  [10.1080/1539445X.2020.1853163]
5. Xu Li, Yue Yuan, Rui Zhao, Di Shao, Shuyun Bi.  (2021)  Assessment on the binding characteristics of residual marbofloxacin in animal-derived food to bovine/human serum albumin by spectroscopy and molecular modelling.  LUMINESCENCE,  36  (4): (977-985).  [PMID:33538386] [10.1002/bio.4022]
6. Gongxi Qiao, Gui Chen, Qin Wen, Wanqiang Liu, Jinwei Gao, Zhiqiang Yu, Qianming Wang.  (2020)  Rapid conversion from common precursors to carbon dots in large scale: Spectral controls, optical sensing, cellular imaging and LEDs application.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  580  (88).  [PMID:32682119] [10.1016/j.jcis.2020.07.034]
7. Rui Zhao, Shuyun Bi, Di Shao, Xiaoyue Sun, Xu Li.  (2020)  Rapid determination of marbofloxacin by surface-enhanced Raman spectroscopy of silver nanoparticles modified by β-cyclodextrin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  229  (118009).  [PMID:31927237] [10.1016/j.saa.2019.118009]
8. Wang Nan, Wang Yan-Fei, Omer Ahmed M., Ouyang Xiao-kun.  (2017)  Fabrication of novel surface-imprinted magnetic graphene oxide-grafted cellulose nanocrystals for selective extraction and fast adsorption of fluoroquinolones from water.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  409  (28): (6643-6653).  [PMID:28940000] [10.1007/s00216-017-0619-9]
9. Zhao-Hong Hu, Yan–Fei Wang, Ahmed Mohamed Omer, Xiao–kun Ouyang.  (2018)  Fabrication of ofloxacin imprinted polymer on the surface of magnetic carboxylated cellulose nanocrystals for highly selective adsorption of fluoroquinolones from water.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  107  (453).  [PMID:28890373] [10.1016/j.ijbiomac.2017.09.009]
10. Furong Tang, Ting Zou, Ziyi Wang, Juan Zhang.  (2024)  Fabrication of fluorinated triazine-based covalent organic frameworks for selective extraction of fluoroquinolone in milk.  JOURNAL OF CHROMATOGRAPHY A,  1730  (465078).  [PMID:38889582] [10.1016/j.chroma.2024.465078]
11. Yanyu Song, Xianbo Sun, Long D. Nghiem, Jun Duan, Wen Liu, Yongdi Liu, Zhengqing Cai.  (2024)  Insight into Fe-O-Bi electron migration channel in MIL-53(Fe)/Bi4O5I2 Z-scheme heterojunction for efficient photocatalytic decontamination.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  667  (321).  [PMID:38640652] [10.1016/j.jcis.2024.04.096]
12. Gaoshuang Hu, Ziyang Liu, Yiqin Zhang, Tao Zhao, Zhuqing Xing, Shan Gao, Jianxiong Hao.  (2024)  Quantum dot-based biomimetic fluorescence immunoassays for enrofloxacin detection in animal-derived foods.  Analytical Methods,  [PMID:39545783] [10.1039/D4AY01753F]
13. Ruijie Tang, Lingfei Li, Yaowei Zhu, Minghui Zhan, Jun Zhao, Changlong Jiang, Bianhua Liu.  (2025)  Ratiometric fluorescent sensor for sensitive visualization of full-spectrum fluoroquinolone antibiotic residues in the environment.  MICROCHEMICAL JOURNAL,  212  (113260).  [10.1016/j.microc.2025.113260]
14. Yujiao Li, Yunan Zhang, Qi An, Jingwen Shi, Lixin Liu.  (2024)  Salt Cocrystal and Salt of Marbofloxacin with Butenedioic Acid: Impact of cis–trans Isomerism of Coformer on the Conformation and Properties of Marbofloxacin.  CRYSTAL GROWTH & DESIGN,  24  (3): (1339-1349).  [10.1021/acs.cgd.3c01300]
15. Tianci Lv, Fubin Liu, Mengqian Xiao, Ying Liu, Litao Wang, Guihua Gao.  (2025)  Synthesis of reusable hierarchical Pore PVDF-MIL-101(Cr) foam for Solid phase extraction of fluoroquinolones from water and its adsorption behavior for anionic and cationic dyes.  JOURNAL OF CHROMATOGRAPHY A,  1740  (465577).  [PMID:39637615] [10.1016/j.chroma.2024.465577]

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